Protein Alignment Cip4 and fnbp1l

DIOPT Version :9

• Sequence 1: NP_001097501.1
• Gene: Cip4 / 38534
• FlyBaseID: FBgn0035533
• Length: 665
• Species: Drosophila melanogaster
• Sequence 2: XP_031755872.1
• Gene: fnbp1l / 448740
• XenbaseID: XB-GENE-489112
• Length: 555
• Species: Xenopus tropicalis
• Alignment Length: 600
• Identity: 230/600 - (38%)
• Similarity: 344/600 - (57%)
• Gaps: 57/600 - (9%)

  Fly    65 MSWGTELWDQNENLAIHTNRGIDALDKFANFLRDRVAIETEYAGKLRRLVKNYQPKKK-EEEDNE 128
            ||||||||||.:||..||..|||.|||:|.|:::|:.||..||.:||.|||.|.||:. ::|:..
 Frog     1 MSWGTELWDQFDNLEKHTQWGIDFLDKYAKFVKERLEIEQNYAKQLRNLVKKYCPKRSAKDEEPR 65

  Fly   129 FTSVQAFRNLLKEVGDLAGQREVVSESLQLQIIAGVTLLSKTLREERKKCLSDGATLQQNLTTQL 193
            |||..:|.|:|.|:.|.|||||||:|.:..::.|.:...|..::.|||..|.:|...||.|...|
 Frog    66 FTSCLSFYNILNELNDYAGQREVVAEEMGHRVYAEIMRYSNDIKGERKSHLQEGRKAQQYLDMCL 130

  Fly   194 SSLDRAKRNYEKAYRDSEKAVDSYKRADMDLNLSRAEVERYKNVMTSKIQQSDDAKNEYANQLQK 258
            ..:|.:||.:|:..|::|||..:|:|.|.|.|.::::||:.|..:..:...:|::|||||.|||.
 Frog   131 KQMDNSKRKFERECREAEKAQQTYERLDNDSNATKSDVEKAKQQLHLRTHMADESKNEYAAQLQN 195

  Fly   259 TNNLQQQHYSMLLPSVLNRLQELDEKRTRGFREFIVGAADVESSVAPIIARCMEGIVKAGESINE 323
            .|..|.:|:.:::|.|...|||:||:||....|...|.||.|..|.|||::|:||:|:|.:|::|
 Frog   196 YNAEQHKHFYIVIPQVYKHLQEMDERRTVKLSECYKGFADAERKVIPIISKCLEGMVQAAKSVDE 260

  Fly   324 KEDTFKVIERYQSGFTPPRDIPFEDLSKCDPDSVQDSHYSNSTSNHLTIRGTMSANKLKKRVGIF 388
            :.|:..|::.::|||.|..|.||||.|:....:|.|...|......|.....::..|.|.::.:|
 Frog   261 RRDSQIVVDCFKSGFEPNGDYPFEDYSQHIYRTVSDGTISTPKQESLKPDPRVTVGKAKGKLWLF 325

  Fly   389 NIFGSNKNSLTADGQKEDFSDLPPNQRRKKLQAKIAELTQNIAQETKARDGLMKMKIVYEANSSL 453
            .  ...|.||......||||.|||.||||:||.:|.||::.:.:|...:|.|.|||.|||.|..:
 Frog   326 G--KKPKWSLRMGPALEDFSHLPPEQRRKRLQQRIDELSRELQKEMDQKDALNKMKDVYEKNPQM 388

  Fly   454 GNPMTVEGQLNESEHKLEKLKVDLKKYQGFLEKASQVPTATSSPQASRNQLQNGHRTSRHSNGSA 518
            |:|.::..::.|:...:|:|::::.|.:.:|   |:|....|         |...|  ||   ||
 Frog   389 GDPSSLHPKIAETTSNIERLRMEIHKNEAWL---SEVEGKVS---------QRSER--RH---SA 436

  Fly   519 DDHHDDGDDQPDDAGSLSRSDSEDNVAQIQNGHNNNNNGSASPESGLGTSHTSLPGSGQGSANEN 583
            :.:|                    .|||          |..||| |..|...:..|..|...:.:
 Frog   437 EANH--------------------LVAQ----------GRESPE-GSYTEDANQEGRVQPQPHAH 470

  Fly   584 AIGEDTYYETEVETLNPVGKCRALYPFEASSEGSIPMSEGEELQVIEIDQGDGWTRVRRENNSNG 648
            ...:|.:  .:.|.|..:|.|::||||:.::||::.|.|||.|.:||.|:||||||.|::|.
 Frog   471 PEFDDEF--DDDEPLPAIGHCKSLYPFDGNNEGTLAMKEGEVLYIIEEDKGDGWTRARKQNG--- 530

  Fly   649 WDEGFVPTSYIEITL 663
             :||:||||||:|||
 Frog   531 -EEGYVPTSYIDITL 544

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cip4	NP_001097501.1	F-BAR_CIP4-like	69..319	CDD:153337	110/250 (44%)
		HR1_CIP4-like	412..488	CDD:212009	27/75 (36%)
		SH3_CIP4-like	603..661	CDD:212844	31/57 (54%)
fnbp1l	XP_031755872.1	F-BAR_FNBP1L	5..256	CDD:153359	110/250 (44%)
		HR1_CIP4_FNBP1L	346..426	CDD:212018	30/82 (37%)
		SH3_FNBP1L	487..543	CDD:213005	32/59 (54%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	77	1.000	Domainoid score	I8706
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	378	1.000	Inparanoid score	I2032
OMA	1	1.010	-	-		QHG51860
OrthoDB	1	1.010	-	-		D348563at2759
OrthoFinder	1	1.000	-	-		FOG0001169
OrthoInspector	1	1.000	-	-		otm47719
Panther	1	1.100	-	-	O	PTHR15735
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2056
SonicParanoid	1	1.000	-	-		X890
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	11	11.110