Protein Alignment Cip4 and Synd

DIOPT Version :9

• Sequence 1: NP_001097501.1
• Gene: Cip4 / 38534
• FlyBaseID: FBgn0035533
• Length: 665
• Species: Drosophila melanogaster
• Sequence 2: NP_001262786.1
• Gene: Synd / 42467
• FlyBaseID: FBgn0053094
• Length: 495
• Species: Drosophila melanogaster
• Alignment Length: 622
• Identity: 111/622 - (17%)
• Similarity: 215/622 - (34%)
• Gaps: 197/622 - (31%)

  Fly    82 TNRGIDALDKFAN----FLRDRVAIETEYAGKLRRLVKNYQPKKKEEEDNEF-TSVQAFRNLLKE 141
            |.:.|:...|..|    .:::|..||..||..||...|.:  .:..|:..|: |:..|::.:|.|
  Fly    26 TTKRIEDGYKLCNDLQQLIQERADIEKGYAKSLRTWSKKW--GELIEKGPEYGTTEAAWKGVLTE 88

  Fly   142 VGDLAGQREVVSESLQLQIIAGV----------TLLS----KTLREERKKCLSDGATLQQNLTTQ 192
            ...::.....:.::|...:.:.:          ||:.    |.|.:..||.....|.|
  Fly    89 SERISDVHMKIKDNLCNDVNSQIKTWQKENYHHTLMQIKERKDLEDLFKKAQKPWAKL------- 146

  Fly   193 LSSLDRAKRNYEKAYRDSEKAVDSYKRADMDLNLSRAEVERYKNVMTSKIQQSDDAKNEYANQLQ 257
            |:.:::||.:|..|.:....|.:..:.|:.|.:||..:|::    |..::|::.|       |:|
  Fly   147 LAKVEKAKADYHSACKTERSATNQERNANADSSLSPDQVKK----MHDRVQKTKD-------QVQ 200

  Fly   258 KTNNLQQQHYSML----------LPSVLNRLQELDEKRTRGFREFIVGAADVESSVAPIIARCME 312
            |.....:|..:.:          :.||..:.|..::.|.:.|:|.:..           :..|::
  Fly   201 KCREKYEQAIAEITKYNSVYIEDMTSVFEKCQTFEKTRLQFFKEILFN-----------VHSCLD 254

  Fly   313 GIVKAGESINEKEDTFKVIERYQSGFTPPRDIP--FEDLSKCDPDSVQDSHYSNSTSNHLTIRGT 375
                                     .|..:.:|  :|:.|....::.|.......::||
  Fly   255 -------------------------LTKVQSLPQIYEEFSHTINNADQQKDLKWWSNNH------ 288

  Fly   376 MSANKLKKRVGIFNIFGSN--KNSLTADGQKEDFSDLPPNQRRKKL----------QAKIAELTQ 428
                            |.|  .|..:.....|:|.|:....:.|:.          |..:||
  Fly   289 ----------------GINMAMNWPSFVEYTEEFRDIAKGNKSKEALPAAPITLINQRPVAE--- 334

  Fly   429 NIAQETKARDGLMKMKIVYEANSSLGNPMTVEGQLNESEHKLEKLKVDLKKYQGFLEKASQVPTA 493
            ::.||....:.|.|..   ...||:.:..:|:.::..::..:...:............|:...||
  Fly   335 DVHQEYPQTNSLKKNT---STLSSVSSRASVKSEIATTQSSVTTSEAKTSAAVAGAATATAAATA 396

  Fly   494 TSSPQASRNQLQNGHRTSRHSNGSADDHHDDGDDQPDDAGSLSRSDSEDNVAQIQNGHNNNNNGS 558
            .|:.....:.:.||       ||..|.:..|.:::.|::         |||. :.||.
  Fly   397 ASAASNRNSSVTNG-------NGKVDANPFDEEEEWDES---------DNVL-VDNGE------- 437

  Fly   559 ASPESGLGTSHTSLPGSGQGSANENAIGEDTYYETEVETLNPVGKCRALYPFEASSEGSIPMSEG 623
                          ||.                        ||   :|||.:|.:....:...:|
  Fly   438 --------------PGV------------------------PV---KALYDYEGAESDELTFKQG 461

  Fly   624 EELQVIEIDQGDGWTRVRRENNSNGWDEGFVPTSYIE 660
            :..:.:|.:...||.:.|    .|| ..|..|.:|:|
  Fly   462 DVFEKLEDEDEQGWCKGR----MNG-RVGLYPANYVE 493

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cip4	NP_001097501.1	F-BAR_CIP4-like	69..319	CDD:153337	52/265 (20%)
		HR1_CIP4-like	412..488	CDD:212009	11/85 (13%)
		SH3_CIP4-like	603..661	CDD:212844	15/58 (26%)
Synd	NP_001262786.1	F-BAR_PACSIN	17..272	CDD:153339	56/301 (19%)
		SH3_PACSIN	441..493	CDD:212777	16/59 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2056
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.940