Protein Alignment Cip4 and Cip4

DIOPT Version :10

• Sequence 1: NP_001097501.1
• Gene: Cip4 / 38534
• FlyBaseID: FBgn0035533
• Length: 665
• Species: Drosophila melanogaster
• Sequence 2: XP_061501428.1
• Gene: Cip4 / 3290080
• VectorBaseID: AGAMI1_012743
• Length: 619
• Species: Anopheles gambiae
• Alignment Length: 620
• Identity: 397/620 - (64%)
• Similarity: 487/620 - (78%)
• Gaps: 25/620 - (4%)

  Fly    63 NNMSWGTELWDQNENLAIHTNRGIDALDKFANFLRDRVAIETEYAGKLRRLVKNYQPKK-KEEED 126
            |:.:||.|||||.:|:|.||.:|||.:::|..|:|||.|||.|||.||||||||||||| ||:|:
Mosquito     8 NSTTWGKELWDQFDNIATHTQKGIDFIERFGGFIRDRSAIEVEYALKLRRLVKNYQPKKSKEDEE 72

  Fly   127 NEFTSVQAFRNLLKEVGDLAGQREVVSESLQLQIIAGVTLLSKTLREERKKCLSDGATLQQNLTT 191
            |||:|:.||:|:||||.|||||||||:|:||.|::.|:.||:|.|||||||.|:.||:|.|:|.|
Mosquito    73 NEFSSLIAFKNVLKEVADLAGQREVVAENLQNQVLQGILLLAKNLREERKKALNQGASLTQSLHT 137

  Fly   192 QLSSLDRAKRNYEKAYRDSEKAVDSYKRADMDLNLSRAEVERYKNVMTSKIQQSDDAKNEYANQL 256
            |:.:||||||:||||:|::|||::||.:||.|.:||||:||:.:..|..:..||:|||:||||||
Mosquito   138 QIGTLDRAKRSYEKAFREAEKAIESYHKADADFHLSRADVEKQRVNMNIRNSQSEDAKSEYANQL 202

  Fly   257 QKTNNLQQQHYSMLLPSVLNRLQELDEKRTRGFREFIVGAADVESSVAPIIARCMEGIVKAGESI 321
            |.||..|||||.:.||.|.|||||||||||||.:|||..:||||..|:||||.|:||||||.:||
Mosquito   203 QITNKQQQQHYQIALPEVFNRLQELDEKRTRGMKEFIKRSADVEYEVSPIIAHCLEGIVKAADSI 267

  Fly   322 NEKEDTFKVIERYQSGFTPPRDIPFEDLSKCDPDSVQDSHYSNSTS--NHLTIRGTMSANKLKKR 384
            |||:|:..|||:|||||.||.|||||||||.|||:..:|...||::  ||:|.:|| :.:|||||
Mosquito   268 NEKDDSMIVIEKYQSGFQPPGDIPFEDLSKPDPDAANNSQTHNSSTGLNHMTGKGT-TKDKLKKR 331

  Fly   385 VGIFNIFGSN----------KNSLTADGQKEDFSDLPPNQRRKKLQAKIAELTQNIAQETKARDG 439
            ||||.||..|          ||:|:.||.|||||||||.||||||.||:.||.|.:|||..|.||
Mosquito   332 VGIFGIFTGNKKILEACINVKNNLSTDGLKEDFSDLPPTQRRKKLTAKVQELQQKVAQEQAASDG 396

  Fly   440 LMKMKIVYEANSSLGNPMTVEGQLNESEHKLEKLKVDLKKYQGFLEKASQVPTATSSPQASRNQL 504
            |||||.||||||.||:|.|||.|||||.::|::|:.:|.:||..||:|:.......|||::| .:
Mosquito   397 LMKMKGVYEANSMLGDPRTVEEQLNESVNRLDRLRHELLRYQKLLEQANNQSFIQHSPQSNR-VI 460

  Fly   505 QNGHRTSRHSNGSA---DDHHDDGDDQPDDAGSLSRSDSEDNVAQIQNGHNNNNNG-SASPESGL 565
            |||.|:|||||||:   :.|.|:|:|.||||||||||.||.:|.|.|||.|.|||| ||||||||
Mosquito   461 QNGQRSSRHSNGSSNHENSHEDNGEDHPDDAGSLSRSASESSVQQAQNGLNINNNGSSASPESGL 525

  Fly   566 GTSHTSLPGSGQGSANENAIGEDTYYETEVETLNPVGKCRALYPFEASSEGSIPMSEGEELQVIE 630
            ||||||||||||||.||..:.|: :||.:    .|:|.|||||||:|:|||||||||||||||||
Mosquito   526 GTSHTSLPGSGQGSTNEQPMNEE-FYEAD----TPLGTCRALYPFDATSEGSIPMSEGEELQVIE 585

  Fly   631 IDQGDGWTRVRRENNSNGWDEGFVPTSYIEITLYA 665
            :||||||||||| .:|.||:||||||||||.||||
Mosquito   586 VDQGDGWTRVRR-FSSKGWEEGFVPTSYIECTLYA 619

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cip4	NP_001097501.1	F-BAR_CIP4-like	69..319	CDD:153337	162/250 (65%)
		HR1_CIP4-like	412..488	CDD:212009	47/75 (63%)
		SH3_CIP4-like	603..661	CDD:212844	48/57 (84%)
Cip4	XP_061501428.1	None