Protein Alignment Cip4 and Fchsd1

DIOPT Version :10

• Sequence 1: NP_001097501.1
• Gene: Cip4 / 38534
• FlyBaseID: FBgn0035533
• Length: 665
• Species: Drosophila melanogaster
• Sequence 2: NP_001103351.1
• Gene: Fchsd1 / 307482
• RGDID: 1308240
• Length: 690
• Species: Rattus norvegicus
• Alignment Length: 619
• Identity: 130/619 - (21%)
• Similarity: 226/619 - (36%)
• Gaps: 146/619 - (23%)

  Fly    73 DQNENLAIHTNRGIDALDKFANFLRDRVAIETEYAGKLRRL----VKNYQPKKKEEEDNEFTSVQ 133
            :|...|.....|..|.|:...::.:.|.|||.||...|::|    :|....:..|.:....|...
  Rat    20 EQLSILQTRQQREADLLEDIRSYSKQRAAIEREYGQALQKLAGPFLKREGQRSGEVDSRARTVFG 84

  Fly   134 AFRNLLKEVGDLAGQREVVSESLQLQIIAGVTLLSKTLREERKKCLSDGA-TLQQNLTTQLSS-- 195
            |:|.||.  ..:||.:..:..|.:.:.:||     .|.|..:::.|..|. :|||.....|.|
  Rat    85 AWRCLLD--ATVAGGQTRLQASDRYRDLAG-----GTGRSAKEQVLRKGTESLQQAQAEVLQSVR 142

  Fly   196 -LDRAKRNYEKAYR----DSEKAVD---SYKRADMDLNLSRAEVERYKNVMTSK----IQQSDDA 248
             |.|:::.|.:..|    ..|||.|   ...|.|..:..||..:::....::::    .||...|
  Rat   143 ELSRSRKLYGQRERVWALAQEKAADVQARLNRNDHGIFHSRTSLQKLSTKLSAQSAQYSQQLRAA 207

  Fly   249 KNEYANQLQKTNNLQQQHYSMLLPSVLNRL-QELDEKRTRGFREFIVGAADVESSVAPIIARCME 312
            :|||...|..||.....:|...||::|..| .||.|.    .|:.:......|...|.:|.....
  Rat   208 RNEYLLNLVATNAHLAHYYQEELPALLKVLVSELSEY----LRDPLTLLGHTELEAAEMILEHAR 268

  Fly   313 GIVKAGESINEKEDTFKVIERYQSGFTPPRDIPFEDLSKCDPDSVQDSHYSNSTSNHLTIRGT-- 375
            ...||...:|.::|. |:..:....|:|   .|.:.......|.|           |...||.
  Rat   269 HGGKAASQVNWEQDV-KLFLQGPGVFSP---TPPQQFQPAGTDQV-----------HALERGAGG 318

  Fly   376 -MSANKLKKRVGIFNIFGSNKNSLTADGQK-----EDFSDLPPNQRRKKLQAKIAELTQNI--AQ 432
             ...:.|::.|..:....:....:...|.:     |......|.:....::.:|.|:.:||  ||
  Rat   319 MAEESGLEREVQRWTSRAARDYKIQHHGHRVLQRLELRRQQAPEREAPGVEQRIQEVRENIRRAQ 383

  Fly   433 ETKARDGLMKMKIVYEANSSLGNPMTVEGQLNESEHKLEKLKVDLKKYQGFLEKASQVPTATSSP 497
            .::.: |..::.::.||.                        :|::::   |:.|.   |.....
  Rat   384 VSQVK-GAARLALLQEAG------------------------LDVQRW---LKPAM---TQAQDE 417

  Fly   498 QASRNQLQNGHRTSRHSNGSADDHHDDGDDQPDDAGSLSRSDSEDNVAQIQNGHNNNNNGSASPE 562
            .....:|.....:.|..:.:|:|......|:.::||.|....:...:|.
  Rat   418 VEQERRLSEARLSQRDLSPTAEDAELSDFDECEEAGELFEEPAPPALAT---------------- 466

  Fly   563 SGLGTSHTSLPGSGQGSANENAIGEDTYYETEVETLNPVGKCRA--LYPFEASSEGSIPMSEGEE 625
                   .:||                              |.|  ::.::|..|..:.::|||.
  Rat   467 -------RALP------------------------------CPAHVVFGYQAGREDELTITEGEW 494

  Fly   626 LQVIEIDQGDGWTRVRRENNSNGWDEGFVPTSYI 659
            |:|||....|.|.:.|   |.:| :.||||..|:
  Rat   495 LEVIEEGDADEWVKAR---NQHG-EAGFVPERYL 524

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cip4	NP_001097501.1	F-BAR_CIP4-like	69..319	CDD:153337	69/265 (26%)
		HR1_CIP4-like	412..488	CDD:212009	12/77 (16%)
		SH3_CIP4-like	603..661	CDD:212844	21/59 (36%)
Fchsd1	NP_001103351.1	BAR	16..275	CDD:472257	69/265 (26%)
		SH3_FCHSD_1	470..526	CDD:212695	22/89 (25%)
		SH3	550..607	CDD:473055