Protein Alignment Cip4 and Fchsd2

DIOPT Version :10

• Sequence 1: NP_001097501.1
• Gene: Cip4 / 38534
• FlyBaseID: FBgn0035533
• Length: 665
• Species: Drosophila melanogaster
• Sequence 2: NP_950177.2
• Gene: Fchsd2 / 207278
• MGIID: 2448475
• Length: 764
• Species: Mus musculus
• Alignment Length: 618
• Identity: 119/618 - (19%)
• Similarity: 246/618 - (39%)
• Gaps: 145/618 - (23%)

  Fly    87 DALDKFANFLRDRVAIETEYAGKLRRLVKNY----QPKKKEEEDNEFTSV-QAFRNLLKEVGDLA 146
            |.|:....|.:.:.|||.|||..:::|...|    .|..|.::.|::.|: ..:::.|:....:|
Mouse    34 DLLEDMRTFSQKKAAIEREYAQGIQKLASQYLKRDWPGIKTDDRNDYRSMYPVWKSFLEGTMQVA 98

  Fly   147 GQREVVSESLQLQIIAGVTLLSKTLREER-KKCLSDGATLQQNLTTQLSSLDRAKRNYEKAYRDS 210
            ..|..:.|:.: ..|:......::|:|:: |:|:.....:|..|...:..|.:.|:.|   :...
Mouse    99 QSRINICENYK-NFISEPARAVRSLKEQQLKRCVDQLTKIQTELQETVKDLVKGKKKY---FETE 159

  Fly   211 EKAVDSYKRADMD----LNLSRAEVERYKNVMTSKIQQSD------DAKNEYANQLQKTNNLQQQ 265
            :.|....::||::    |:|.::.:...|..:..|.::|:      .|:|:|...|...|..|.:
Mouse   160 QMAHAVREKADIEAKSKLSLFQSRISLQKASVKLKARRSECNTKATHARNDYLLTLAAANAHQDR 224

  Fly   266 HYSMLLPSVLNRLQELDEKRTRGFREFIVGAADVESSVAPIIARCMEGIVKAGESINEKEDTFKV 330
            :|.   ..::|.::.||.......:::::..:..|......|....:.::         |::.||
Mouse   225 YYQ---TDLVNIMKALDGNVYDHLKDYLIAFSRTELETCQAIQNTFQFLL---------ENSSKV 277

  Fly   331 IERY--------QSGFTPPRDIPFEDLSKCDPDS------VQDSHYSNSTSNHLTIRGTMSANKL 381
            :..|        .:.|..|:...|:   .||.|:      :.|...|..::..:||   ..:.:|
Mouse   278 VRDYNLQLFLQENAVFHKPQPFQFQ---PCDSDTSLKAAQLVDIELSPVSALRMTI---AESRQL 336

  Fly   382 KKRVGIFNIFGSNKNSLTADGQKEDFSDLPPNQRRKKLQAKIAELTQNIAQETKARDGLMKMKIV 446
            :...|.     :.::||              |:..:|...::|...:||..:.:..:.|....:.
Mouse   337 ESETGT-----TEEHSL--------------NKEARKWATRVAREHKNIVHQQRVLNELECHGVA 382

  Fly   447 YEANSSLGNPMTVEGQLNESEHKLEKLKVDLKKYQGFLEKASQVPTATSS-PQASRNQ----LQN 506
            ....|.    ..:|.:::|:...:.|.::...|.:..|:...|:..:..: .:::.||    |:|
Mouse   383 LSEQSR----AELEQKIDEARESIRKAEIIKLKAEARLDLLKQIGVSVDTWLKSAMNQVMEELEN 443

  Fly   507 GHRTSR----HSNG-----SADDHHDDGDDQPDDAGSLSRSDSEDNVAQIQNGHNNNNNGSASPE 562
             .|.:|    .|||     :||...::|:            :.|||:...       ::.|:||.
Mouse   444 -ERWARPPAVTSNGTLHSLNADAEREEGE------------EFEDNMDVF-------DDSSSSPS 488

  Fly   563 SGLGTSHTSLPGSGQGSANENAIGEDTYYETEVETLNPVGKCRALYPFEASSEGSIPMSEGEELQ 627
            ..|                      ..|..|          |:.:|.::||....:.:.|.|.|:
Mouse   489 GTL----------------------RNYPLT----------CKVVYSYKASQPDELTIEEHEVLE 521

  Fly   628 VIEIDQGDGWTRVRRENNSNGWDEGFVPTSYIE 660
            |||....:.|.:.|   |..| ..|:||..|::
Mouse   522 VIEDGDMEDWVKAR---NKVG-QVGYVPEKYLQ 550

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cip4	NP_001097501.1	F-BAR_CIP4-like	69..319	CDD:153337	49/247 (20%)
		HR1_CIP4-like	412..488	CDD:212009	12/75 (16%)
		SH3_CIP4-like	603..661	CDD:212844	18/58 (31%)
Fchsd2	NP_950177.2	F-BAR_FCHSD2	16..275	CDD:153361	50/256 (20%)
		SH3_FCHSD_1	495..551	CDD:212695	19/70 (27%)
		SH3_FCHSD2_2	595..650	CDD:212827