Protein Alignment Cip4 and Fnbp1

DIOPT Version :10

• Sequence 1: NP_001097501.1
• Gene: Cip4 / 38534
• FlyBaseID: FBgn0035533
• Length: 665
• Species: Drosophila melanogaster
• Sequence 2: XP_063139128.1
• Gene: Fnbp1 / 192348
• RGDID: 621350
• Length: 649
• Species: Rattus norvegicus
• Alignment Length: 687
• Identity: 228/687 - (33%)
• Similarity: 348/687 - (50%)
• Gaps: 137/687 - (19%)

  Fly    65 MSWGTELWDQNENLAIHTNRGIDALDKFANFLRDRVAIETEYAGKLRRLVKNYQPKK--KEEEDN 127
            ||||||||||.:||..||..|||.|:|:..|:::|..||..||.:||.|.|.|||||  ||||:.
  Rat     1 MSWGTELWDQFDNLEKHTQWGIDILEKYIKFVKERTEIELSYAKQLRNLSKKYQPKKNSKEEEEY 65

  Fly   128 EFTSVQAFRNLLKEVGDLAGQREVVSESLQLQIIAGVTLLSKTLREERKKCLSDGATLQQNLTTQ 192
            ::|:.:||.:.|.|:.|.|||.||:||::..||...:....:.|::|||....||...||::.|.
  Rat    66 KYTACKAFLSTLNELNDYAGQHEVISENMTSQITVDLVRYVQELKQERKSNFHDGRKAQQHIETC 130

  Fly   193 LSSLDRAKRNYEKAYRDSEKAVDSYKRADMDLNLSRAEVERYKNVMTSKIQQSDDAKNEYANQLQ 257
            ...|:.:||.:|:..:::::|...:::.|.|:|:::|:||:.:.....:.|.::|:|.:|:..||
  Rat   131 WKQLESSKRRFERDCKEADRAQQYFEKMDADINVTKADVEKARQQAQMRQQMAEDSKADYSLILQ 195

  Fly   258 KTNNLQQQHYSMLLPSVLNRLQELDEKRTRGFREFIVGAADVESSVAPIIARCMEGIVKAGESIN 322
            :.|..|.::|...:|::..::||::|:|.....|.:...|:|:..|.|||.:|::|||||.|||:
  Rat   196 RFNQEQWEYYHTHIPNIFQKIQEMEERRIVRIGESMKTYAEVDRQVIPIIGKCLDGIVKAAESID 260

  Fly   323 EKEDTFKVIERYQSGFTPPRDIPFEDLSKCDPDSVQDSHYSNS---------------------- 365
            :|.|:..|:|.|:|||.||.||.|||.::....:|.|:..|:|
  Rat   261 QKNDSQLVVEAYKSGFEPPGDIEFEDYTQPMKRTVSDNSLSSSKEGKPELKFGGKSRGKLWPFIK 325

  Fly   366 --------TSNH-------------LTIRGTMSANKLKKRVG-IFNIFGSNK------NSLTADG 402
                    ||.|             ....|..|..:.|:.:. .||.|.::|      .||....
  Rat   326 KNKLMTLLTSPHQPPPPPPASASPSAVPNGPQSPKQQKEPLSHRFNEFMTSKPKIHCFRSLKRGT 390

  Fly   403 QK----------------------------------EDFSDLPPNQRRKKLQAKIAELTQNIAQE 433
            |.                                  ||||:.||.|||||||.|:.:|.:.|.:|
  Rat   391 QSLCYHKELMKRTLGKPTHALEARNYVLSLKLGVTPEDFSNFPPEQRRKKLQQKVDDLNKEIQKE 455

  Fly   434 TKARDGLMKMKIVYEANSSLGNPMTVEGQLNESEHKLEKLKVDLKKYQGFL-EKASQVPTATSSP 497
            |..||.:.|||.||..|..:|:|.:::.:|.|....:|||:::..|::.:| |...::|  ..|.
  Rat   456 TDQRDAITKMKDVYLKNPQMGDPASLDHKLAEVTQNIEKLRLEAHKFEAWLAEVEGRLP--ARSE 518

  Fly   498 QASRNQ-LQNGHRTSRHSNGSADDHHDDGDDQPDDAGSLSRSDSEDNVAQIQNGHNNNNNGSASP 561
            ||.|.. |.:|......:|.:.|                 |..|.|              ||.:.
  Rat   519 QARRQSGLYDGQTHQTVTNCAQD-----------------RESSPD--------------GSYTE 552

  Fly   562 ESGLGTSHTSLPGSGQGSANENAIGEDTYYETEVETLNPVGKCRALYPFEASSEGSIPMSEGEEL 626
            |....:.|..|           |...|..::.| |.|..:|.|:|||.||..:||:|.:.|||.|
  Rat   553 EQSQESEHKVL-----------ATDFDDEFDDE-EPLPAIGTCKALYTFEGQNEGTISVVEGETL 605

  Fly   627 QVIEIDQGDGWTRVRRENNSNGWDEGFVPTSYIEITL 663
            .|||.|:||||||:||..:    :||:|||||:|:.|
  Rat   606 SVIEEDKGDGWTRIRRNED----EEGYVPTSYVEVYL 638

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cip4	NP_001097501.1	F-BAR_CIP4-like	69..319	CDD:153337	96/251 (38%)
		HR1_CIP4-like	412..488	CDD:212009	31/76 (41%)
		SH3_CIP4-like	603..661	CDD:212844	32/57 (56%)
Fnbp1	XP_063139128.1	None