DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cip4 and mlc-7

DIOPT Version :9

Sequence 1:	NP_001097501.1	Gene:	Cip4 / 38534	FlyBaseID:	FBgn0035533	Length:	665	Species:	Drosophila melanogaster
Sequence 2:	NP_001022669.1	Gene:	mlc-7 / 176811	WormBaseID:	WBGene00023451	Length:	153	Species:	Caenorhabditis elegans

Alignment Length:	112	Identity:	24/112 - (21%)
Similarity:	43/112 - (38%)	Gaps:	30/112 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 LAQITKKKT-------------VADLEAECVHSAIAFTCVRVCAKLLASGSSRSSSNNKLAESEN 57
            ||:::|.:|             ...:||.|..|    |.::....||:......:....|.|.::
Worm    46 LAEVSKARTSGARITVEEFIPIYKKVEAACGRS----TTLKEFQTLLSHFDREGNGQIMLMELKS 106

  Fly    58 SAQNS---------NNMSWGTELWDQNENLAIHTNR----GIDALDK 91
            ..||.         :|:.:|.|:.|...|:....||    |::..:|
Worm   107 MLQNGGEKMTNQEVDNLLFGVEVVDGRININNFLNRHLQMGLEESEK 153

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cip4	NP_001097501.1	F-BAR_CIP4-like	69..319	CDD:153337	7/27 (26%)
		HR1_CIP4-like	412..488	CDD:212009
		SH3_CIP4-like	603..661	CDD:212844
mlc-7	NP_001022669.1	FRQ1	8..139	CDD:227455	20/96 (21%)
		EFh	9..65	CDD:298682	4/18 (22%)
		EF-hand_8	55..109	CDD:290545	9/57 (16%)
		EFh	83..140	CDD:298682	11/56 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3565
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900