Protein Alignment Cip4 and Fnbp1

DIOPT Version :10

• Sequence 1: NP_001097501.1
• Gene: Cip4 / 38534
• FlyBaseID: FBgn0035533
• Length: 665
• Species: Drosophila melanogaster
• Sequence 2: XP_006497754.1
• Gene: Fnbp1 / 14269
• MGIID: 109606
• Length: 649
• Species: Mus musculus
• Alignment Length: 687
• Identity: 225/687 - (32%)
• Similarity: 353/687 - (51%)
• Gaps: 137/687 - (19%)

  Fly    65 MSWGTELWDQNENLAIHTNRGIDALDKFANFLRDRVAIETEYAGKLRRLVKNYQPKK--KEEEDN 127
            ||||||||||.:||..||..|||.|:|:..|:::|..||..||.:||.|.|.|||||  ||||:.
Mouse     1 MSWGTELWDQFDNLEKHTQWGIDILEKYIKFVKERTEIELSYAKQLRNLSKKYQPKKNSKEEEEY 65

  Fly   128 EFTSVQAFRNLLKEVGDLAGQREVVSESLQLQIIAGVTLLSKTLREERKKCLSDGATLQQNLTTQ 192
            ::|:.:||.:.|.|:.|.|||.||:||::..||...:....:.|::|||....||...||::.|.
Mouse    66 KYTACKAFLSTLNEMNDYAGQHEVISENMTSQITVDLMRYVQELKQERKSNFHDGRKAQQHIETC 130

  Fly   193 LSSLDRAKRNYEKAYRDSEKAVDSYKRADMDLNLSRAEVERYKNVMTSKIQQSDDAKNEYANQLQ 257
            ...|:.:||.:|:..:::::|...:::.|.|:|:::|:||:.:.....:.|.::|:|.:|:..||
Mouse   131 WKQLESSKRRFERDCKEADRAQQYFEKMDADINVTKADVEKARQQAQIRQQMAEDSKADYSLILQ 195

  Fly   258 KTNNLQQQHYSMLLPSVLNRLQELDEKRTRGFREFIVGAADVESSVAPIIARCMEGIVKAGESIN 322
            :.|..|.::|...:|::..::||::|:|.....|.:...|:|:..|.|||.:|::|||||.|||:
Mouse   196 RFNQEQWEYYHTHIPNIFQKIQEMEERRIVRIGESMKTYAEVDRQVIPIIGKCLDGIVKAAESID 260

  Fly   323 EKEDTFKVIERYQSGFTPPRDIPFEDLSKCDPDSVQDSHYSNSTSNHLTIR-GTMSANKL----- 381
            :|.|:..|:|.|:|||.||.||.|||.::....:|.|:..|:|......:| |..|..||
Mouse   261 QKNDSQLVVEAYKSGFEPPGDIEFEDYTQPMKRTVSDNSLSSSKEGKPELRFGGKSRGKLWPFIK 325

  Fly   382 -KKRVGI-------------------------------------FNIFGSNK------NSLTADG 402
             .|.:.:                                     ||.|.::|      .||....
Mouse   326 KNKLMSLLTSPHQPPPPPPASASPSAVPNGPQSPKQPKEPLSHRFNEFMTSKPKIHCFRSLKRGT 390

  Fly   403 QK----------------------------------EDFSDLPPNQRRKKLQAKIAELTQNIAQE 433
            |.                                  ||||:.||.|||||||.|:.:|.:.|.:|
Mouse   391 QSLCYHKELMKRTLGKPTHALEARDYVLSLKLGVTPEDFSNFPPEQRRKKLQQKVDDLNREIQKE 455

  Fly   434 TKARDGLMKMKIVYEANSSLGNPMTVEGQLNESEHKLEKLKVDLKKYQGFL-EKASQVPTATSSP 497
            |..||.:.|||.||..|..:|:|.:::.:|.|....:|||:::.:|::.:| |...::|  ..|.
Mouse   456 TDQRDAITKMKDVYLKNPQMGDPASLDQKLTEVTQNIEKLRLEAQKFEAWLAEVEGRLP--ARSE 518

  Fly   498 QASRNQ-LQNGHRTSRHSNGSADDHHDDGDDQPDDAGSLSRSDSEDNVAQIQNGHNNNNNGSASP 561
            ||.|.. |.:|......:|.:     .|.:..||  ||.:...|:::..::           .:|
Mouse   519 QARRQSGLYDGQTHQTVTNCA-----QDRESSPD--GSYTEEQSQESEHKV-----------LAP 565

  Fly   562 ESGLGTSHTSLPGSGQGSANENAIGEDTYYETEVETLNPVGKCRALYPFEASSEGSIPMSEGEEL 626
            :.                        |..::.| |.|..:|.|:|||.||..:||:|.:.|||.|
Mouse   566 DF------------------------DDEFDDE-EPLPAIGTCKALYTFEGQNEGTISVVEGETL 605

  Fly   627 QVIEIDQGDGWTRVRRENNSNGWDEGFVPTSYIEITL 663
            .|||.|:||||||:||..:    :||:|||||:|:.|
Mouse   606 SVIEEDKGDGWTRIRRNED----EEGYVPTSYVEVYL 638

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cip4	NP_001097501.1	F-BAR_CIP4-like	69..319	CDD:153337	96/251 (38%)
		HR1_CIP4-like	412..488	CDD:212009	31/76 (41%)
		SH3_CIP4-like	603..661	CDD:212844	32/57 (56%)
Fnbp1	XP_006497754.1	F-BAR_FBP17	5..257	CDD:153360	96/251 (38%)
		HR1	434..510	CDD:469609	31/75 (41%)
		SH3_FBP17	581..637	CDD:213004	34/59 (58%)