Protein Alignment Cip4 and Trip10

DIOPT Version :9

• Sequence 1: NP_001097501.1
• Gene: Cip4 / 38534
• FlyBaseID: FBgn0035533
• Length: 665
• Species: Drosophila melanogaster
• Sequence 2: XP_038938836.1
• Gene: Trip10 / 116717
• RGDID: 621145
• Length: 603
• Species: Rattus norvegicus
• Alignment Length: 663
• Identity: 226/663 - (34%)
• Similarity: 351/663 - (52%)
• Gaps: 125/663 - (18%)

  Fly    65 MSWGTELWDQNENLAIHTNRGIDALDKFANFLRDRVAIETEYAGKLRRLVKNYQPKKKEEEDNE- 128
            |.||||||||.|.|..||..|:|.|||:..|:::||.:|..||.:||.|||.|.||:..::|.|
  Rat     1 MDWGTELWDQFEVLERHTQWGLDLLDKYVKFVKERVEVEQSYAKQLRSLVKKYLPKRPAKDDPEI 65

  Fly   129 -FTSVQAFRNLLKEVGDLAGQREVVSESLQLQIIAGVTLLSKTLREERKKCLSDGATLQQNLTTQ 192
             |:..|:|..||:||.|.|||||:|:|||.:::...:...|:.:::|||....:|...||.|...
  Rat    66 KFSQQQSFVQLLQEVNDFAGQRELVAESLGIRVCLELAKYSQEMKQERKMHFQEGRRAQQQLENG 130

  Fly   193 LSSLDRAKRNYEKAYRDSEKAVDSYKRADMDLNLSRAEVERYKNVMTSKIQQSDDAKNEYANQLQ 257
            ...|:.:||.:|:..|::|||..:.:|.|.|:|.::|:||:.|.....:...::::|||||.|||
  Rat   131 FKQLENSKRKFERDCREAEKAAHTAERLDQDINATKADVEKAKQQAHLRNHMAEESKNEYAAQLQ 195

  Fly   258 KTNNLQQQHYSMLLPSVLNRLQELDEKR-TRGFREFIVGA-----ADVESSVAPIIARCMEGIVK 316
            :.|..|...|...:|.:.::||::||:| ||      :||     ::.|..|.|||.:|:||:..
  Rat   196 RFNRDQAHFYFSQMPQIFDKLQDMDERRATR------LGAGYGLLSEAELQVVPIIGKCLEGMKV 254

  Fly   317 AGESINEKEDTFKVIERYQSGFTPPRDIPFEDLSKC-----------DPDSVQDSHYSNSTSN-- 368
            |.||::.|.|:..:||.::|||..|.|:.|||.|:.           .||...:...::|.|.
  Rat   255 AAESVDAKNDSKVLIELHKSGFARPGDLEFEDFSQVMNRVPSDSSLGTPDGRPELRAASSRSRAK 319

  Fly   369 -------------HLTIRG-----TMS-------------------ANKLKKRVGIF-NIFGSNK 395
                         .|::.|     |:|                   :..:|.|:..| ::.||..
  Rat   320 RWPFGKKNKPRPPSLSLLGGHLPSTLSDGPSSPRSGRDPLAILSEISKSVKPRLASFRSLRGSRG 384

  Fly   396 NSLTADGQKEDFSDLPPNQRRKKLQAKIAELTQNIAQETKARDGLMKMKIVYEANSSLGNPMTVE 460
            ..:|     ||||.|||.|:||:||.::.|..:.:.:|...|:.|.|||.|||....:|:|.::|
  Rat   385 TVVT-----EDFSHLPPEQQRKRLQQQLEERNRELQKEEDQREALKKMKDVYEKTPQMGDPASLE 444

  Fly   461 GQLNESEHKLEKLKVDLKKYQGFLEKASQVPTATSSPQASRNQLQNGHRTSRHSNGSADDHHDDG 525
            .::.|:...:|:||::::||:.:|.:|.           ||.....|...|||:
  Rat   445 PRIAETLGNIERLKLEVQKYEAWLAEAE-----------SRVLSNRGDSLSRHT----------- 487

  Fly   526 DDQPDDAGSLSRSDSEDNVAQIQNGHNNNNNGSASPESGLGTSHTSLPGSGQGSANENAIGEDTY 590
              :|.|..:.:..||..         ::||:||...:.           |.:...:|.  |:||.
  Rat   488 --RPPDPPTTAPPDSSS---------SSNNSGSQDNKE-----------SSEEPPSEE--GQDTP 528

  Fly   591 YETEV-----ETLNPVGKCRALYPFEASSEGSIPMSEGEELQVIEIDQGDGWTRVRRENNSNGWD 650
            ..||.     |..:|:|:|.|:|.||.||||::.|||||:|.::|.|:|||||||||:...
  Rat   529 IYTEFDEDFEEPASPIGQCVAIYHFEGSSEGTVSMSEGEDLSLMEEDKGDGWTRVRRKQGG---- 589

  Fly   651 EGFVPTSYIEITL 663
            ||:|||||:.:||
  Rat   590 EGYVPTSYLRVTL 602

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cip4	NP_001097501.1	F-BAR_CIP4-like	69..319	CDD:153337	102/257 (40%)
		HR1_CIP4-like	412..488	CDD:212009	26/75 (35%)
		SH3_CIP4-like	603..661	CDD:212844	33/57 (58%)
Trip10	XP_038938836.1	F-BAR_CIP4-like	5..257	CDD:153337	102/257 (40%)
		HR1_CIP4_FNBP1L	395..475	CDD:212018	29/90 (32%)
		SH3_CIP4-like	546..600	CDD:212844	33/57 (58%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	203	1.000	Domainoid score	I2861
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	359	1.000	Inparanoid score	I2141
OMA	1	1.010	-	-		QHG51860
OrthoDB	1	1.010	-	-		D348563at2759
OrthoFinder	1	1.000	-	-		FOG0001169
OrthoInspector	1	1.000	-	-		otm44676
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR15735
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X890
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	10	10.080