DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15014 and thumpd1

DIOPT Version :9

Sequence 1:	NP_647892.1	Gene:	CG15014 / 38533	FlyBaseID:	FBgn0035532	Length:	324	Species:	Drosophila melanogaster
Sequence 2:	NP_989059.1	Gene:	thumpd1 / 394656	XenbaseID:	XB-GENE-5742238	Length:	290	Species:	Xenopus tropicalis

Alignment Length:	318	Identity:	106/318 - (33%)
Similarity:	159/318 - (50%)	Gaps:	38/318 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MEPASKKSKMGKNVKFNNNKKKYFHAKRQTLQPGQRGFFATCNINEKACVRECYNLLNHYADILY 65
            |....:|.|.....:|..|.|:  ..:|..|:.|.:|...|||:||:.||.|.|:|||.|.|.:|
Frog     1 MSTDGQKGKKRYKSQFCGNAKR--QKRRHELEVGMQGILITCNMNERKCVAEAYSLLNEYGDQMY 63

  Fly    66 GSEKPENEPEKKQPEEGAGGDAGEDDPKPAAGGTSDDDDDLEAAAAK----CREMLSQRKMRFQN 126
            |   ||...||             ||   ....:.::|||.|||..|    .|....:...|||:
Frog    64 G---PEKLSEK-------------DD---GLSESEEEDDDAEAALKKEVDQIRTSTEKNLRRFQS 109

  Fly   127 VDTNTTNCVFIRTQLEDPVALGKHIINDIATTGKSMSRFVLRLVPIEVVCRANMPDIITAAGELF 191
            |::...|.:||||...:|..|..||:.|:.||.|..:|.:||::|:...|:|.:.|:...| |.|
Frog   110 VESGANNVIFIRTLNVEPEKLVHHILKDVHTTKKKKTRVILRMLPVSGTCKAFLEDLKKYA-ETF 173

  Fly   192 DKHFLKEPT--SYGIIFNHRYNQQIKRDQIITQLAELVNSKNVGNKVDLKEAKKSIIVEVLRGWC 254
            ...:.|.|.  ::.|.:..|.|..:.||::|.:||.:|.|:|..|||||...:.::|||:::..|
Frog   174 FAPWFKSPNKGTFQIAYKARNNNHMNRDEVIKELAGIVASQNPENKVDLSNPEYTVIVEIIKNVC 238

  Fly   255 LLSVIDNYLECKKFNLAELANPSDKKSSGEGDSKSETSEVANGNDKEQAESSEESKSN 312
            ..||:.:|...:|:||.|:.     |||.|...:..|.|     |||:.....:...|
Frog   239 CFSVVKDYTVFRKYNLQEVI-----KSSKEEKPQQPTKE-----DKEENLKETQGTQN 286

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15014	NP_647892.1	THUMP_THUMPD1_like	123..260	CDD:212586	51/138 (37%)
thumpd1	NP_989059.1	THUMP_THUMPD1_like	35..244	CDD:212586	82/228 (36%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	68	1.000	Domainoid score	I9591
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H5878
Inparanoid	1	1.050	160	1.000	Inparanoid score	I4144
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1478461at2759
OrthoFinder	1	1.000	-	-		FOG0004286
OrthoInspector	1	1.000	-	-		oto103293
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X4662
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	7.060