DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG15014 and Thumpd1

DIOPT Version :9

Sequence 1:	NP_647892.1	Gene:	CG15014 / 38533	FlyBaseID:	FBgn0035532	Length:	324	Species:	Drosophila melanogaster
Sequence 2:	NP_001009688.1	Gene:	Thumpd1 / 309041	RGDID:	1308854	Length:	353	Species:	Rattus norvegicus

Alignment Length:	332	Identity:	111/332 - (33%)
Similarity:	170/332 - (51%)	Gaps:	52/332 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 SKKSKMGKNVKFNNNKKKYFHAKR---------QTLQPGQRGFFATCNINEKACVRECYNLLNHY 60
            |..|..||    ...|.::..|||         :.|:||.:|...|||:||:.||.|.|:|||.|
  Rat     8 SPPSVGGK----RKGKSQFLPAKRARRCDAGGPRQLEPGLQGILITCNMNERKCVEEAYSLLNEY 68

  Fly    61 ADILYGSEKPENEPEKKQPEEGAGGDAGEDDPKPAAGGTSDDDDDLEAAAAK----CREMLSQRK 121
            .|.:||   ||...:|.|...|:.|                :|||.|||..|    .:....:|.
  Rat    69 GDDMYG---PEKFIDKDQQPSGSEG----------------EDDDAEAALKKEVGDIKASTEKRL 114

  Fly   122 MRFQNVDTNTTNCVFIRTQLEDPVALGKHIINDIATTGKSMSRFVLRLVPIEVVCRANMPDIITA 186
            .|||:|::...|.|||||...:|..|..||:.|:..|.|..:|.:||::|:...|:|.:.|:...
  Rat   115 RRFQSVESGANNVVFIRTLGIEPEKLVHHILQDMYKTKKKKTRVILRMLPVSGTCKAFLEDMKKY 179

  Fly   187 AGELFDKHFLKEPT--SYGIIFNHRYNQQIKRDQIITQLAELVNSKNVGNKVDLKEAKKSIIVEV 249
            | |.|.:.:.|.|.  ::.|::..|.|..:.|:::|.:||.:|.|.|..|||||...:.:::||:
  Rat   180 A-ETFLEPWFKAPNKGTFQIVYKSRNNSHMNREEVIKELAGIVGSLNSENKVDLTNPEYTVVVEI 243

  Fly   250 LRGWCLLSVIDNYLECKKFNLAEL------ANPSDKKSSG-----EGDSKSETSEVANGNDKEQA 303
            ::..|.|||:.:|:..:|:||.|:      :.|..|..:|     |..||...::...|.:.:||
  Rat   244 IKAVCCLSVVKDYVLFRKYNLQEVVKSAKDSRPPPKLGNGKEAQLEPGSKLSQNDPPKGKNNQQA 308

  Fly   304 --ESSEE 308
              |||||
  Rat   309 APESSEE 315

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15014	NP_647892.1	THUMP_THUMPD1_like	123..260	CDD:212586	50/138 (36%)
Thumpd1	NP_001009688.1	THUMP_THUMPD1_like	45..254	CDD:212586	81/228 (36%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	66	1.000	Domainoid score	I9720
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H5878
Inparanoid	1	1.050	95	1.000	Inparanoid score	I4963
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1478461at2759
OrthoFinder	1	1.000	-	-		FOG0004286
OrthoInspector	1	1.000	-	-		oto96592
orthoMCL	1	0.900	-	-		OOG6_102910
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X4662
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	11	10.870