DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment PMP34 and PXN

DIOPT Version :9

Sequence 1:	NP_001246615.1	Gene:	PMP34 / 38532	FlyBaseID:	FBgn0052250	Length:	314	Species:	Drosophila melanogaster
Sequence 2:	NP_181526.1	Gene:	PXN / 818584	AraportID:	AT2G39970	Length:	331	Species:	Arabidopsis thaliana

Alignment Length:	331	Identity:	104/331 - (31%)
Similarity:	166/331 - (50%)	Gaps:	47/331 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 VHAVSGAAGGCIAMSTFYPLDTVRSRLQLE--------EAGDVRSTRQVIKEIVLGEGFQSLYRG 73
            ::.::||.||.||....|||.||.:|.|.|        :.|.:....||:|:    ||::.||.|
plant     6 INGLAGAGGGIIAQLLTYPLQTVNTRQQTERDLKREKRKLGTIEHMCQVVKQ----EGWERLYGG 66

  Fly    74 LGPVLQSLCISNFVYFYTFH---------ALKAVASGGSPSQHSALKDLLLGSIAGIINVLTTTP 129
            |.|.|.....|..||:|.:.         ||.....|...........||:.:.||.:|||.|.|
plant    67 LAPSLAGTAASQGVYYYFYQVFRNRAEATALARKKKGLGDGSVGMFASLLVAAFAGSVNVLMTNP 131

  Fly   130 FWVVNTRLRM-------RNVAGTSDEVNKHYKNLLEGLKY--------VAEKEGIAGLWSGTIPS 179
            .||:.||::.       :..|..|...|......:|...|        |.::.||.|.|.|.||:
plant   132 IWVIVTRMQTHRKMTKDQTAAPESPSSNAEALVAVEPRPYGTFNTIREVYDEAGITGFWKGVIPT 196

  Fly   180 LMLVSNPALQFMMYE----MLKRNIMRFTGGEMGSLSFFFIGAIAKAFATVLTYPLQLVQTKQRH 240
            |::||||::|||:||    .||:.........:.:|..|.:||:||..|||.||||.:|:::.:
plant   197 LIMVSNPSMQFMLYETMLTKLKKKRALKGSNNVTALETFLLGAVAKLGATVTTYPLLVVKSRLQ- 260

  Fly   241 RSKESDSKPSTSAGSTPRTESTLELMISILQHQGIRGLFRGLEAKILQTVLTAALMFMAYEKIAG 305
                  :|..|:.....:.:.||:.::.:::::|:.|.::|:..||:|:||.||::||..|::..
plant   261 ------AKQVTTGDKRQQYKGTLDAILKMIRYEGLYGFYKGMSTKIVQSVLAAAVLFMIKEELVK 319

  Fly   306 TVGMLL 311
            ...:||
plant   320 GAKLLL 325

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
PMP34	NP_001246615.1	Mito_carr	15..96	CDD:278578	31/95 (33%)
		Mito_carr	105..202	CDD:278578	38/115 (33%)
		Mito_carr	214..303	CDD:278578	30/88 (34%)
PXN	NP_181526.1	Mito_carr	19..90	CDD:395101	24/74 (32%)
		Mito_carr	107..221	CDD:395101	38/113 (34%)
		Mito_carr	227..319	CDD:395101	31/98 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	64	1.000	Domainoid score	I3697
eggNOG	1	0.900	-	-		E1_COG4266
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	156	1.000	Inparanoid score	I1671
OMA	1	1.010	-	-		QHG53601
OrthoDB	1	1.010	-	-		D1186395at2759
OrthoFinder	1	1.000	-	-		FOG0007252
OrthoInspector	1	1.000	-	-		oto2995
orthoMCL	1	0.900	-	-		OOG6_103707
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	12	11.740