Protein Alignment PMP34 and SLC25A32

DIOPT Version :10

• Sequence 1: NP_728982.1
• Gene: PMP34 / 38532
• FlyBaseID: FBgn0052250
• Length: 314
• Species: Drosophila melanogaster
• Sequence 2: NP_110407.2
• Gene: SLC25A32 / 81034
• HGNCID: 29683
• Length: 315
• Species: Homo sapiens
• Alignment Length: 308
• Identity: 76/308 - (24%)
• Similarity: 154/308 - (50%)
• Gaps: 23/308 - (7%)

  Fly     5 SKLSQVLSYQNFVHAVSGAAGGCIAMSTFYPLDTVRSRLQLEEAGDVRSTRQVIKEIVLG----E 65
            |..|.|..:..:.:.::|.:||.::....:|||.|:.|..:.:..::|.....|...:..    :
Human    12 SAWSTVFRHVRYENLIAGVSGGVLSNLALHPLDLVKIRFAVSDGLELRPKYNGILHCLTTIWKLD 76

  Fly    66 GFQSLYRGLGPVLQSLCISNFVYFYTFHALKAVASGGSPSQHSALKDLLLGSIAGIINVLTTTPF 130
            |.:.||:|:.|.:....:|..:||:.::|:|:..:.|...:..|.:.|:..:.||.:.:..|.|.
Human    77 GLRGLYQGVTPNIWGAGLSWGLYFFFYNAIKSYKTEGRAERLEATEYLVSAAEAGAMTLCITNPL 141

  Fly   131 WVVNTRLRMRNVAGTSDEVNKHYKNLLEGLKYVAEKEGIAGLWSGTIPSLMLVSNPALQFMMYEM 195
            ||..|||.::..| ..:..::.||.:.:.|..:.:.||:.||:.|.:|.|...|:.|||||.||:
Human   142 WVTKTRLMLQYDA-VVNSPHRQYKGMFDTLVKIYKYEGVRGLYKGFVPGLFGTSHGALQFMAYEL 205

  Fly   196 LK----RNIMRFTGGEMGSLSFFFIGAIAKAFATVLTYPLQLVQTKQRHRSKESDSKPSTSAGST 256
            ||    ::|.|....::.::.:..:.|::|.||...|||.|:|      |::..|.....|
Human   206 LKLKYNQHINRLPEAQLSTVEYISVAALSKIFAVAATYPYQVV------RARLQDQHMFYS---- 260

  Fly   257 PRTESTLELMISILQHQGIRGLFRGLEAKILQTVLTAALMFMAYEKIA 304
                ..::::....:.:|:.|.::|:...:::......:.|:.||.::
Human   261 ----GVIDVITKTWRKEGVGGFYKGIAPNLIRVTPACCITFVVYENVS 304

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PMP34	NP_728982.1	Mito_carr	15..96	CDD:395101	19/84 (23%)
		Mito_carr	105..202	CDD:395101	33/100 (33%)
		Mito_carr	214..303	CDD:395101	18/88 (20%)
SLC25A32	NP_110407.2	Solcar 1. /evidence=ECO:0000255|PROSITE-ProRule:PRU00282	20..109		20/88 (23%)
		PTZ00169	26..307	CDD:240302	73/294 (25%)
		Solcar 2. /evidence=ECO:0000255|PROSITE-ProRule:PRU00282	118..209		32/91 (35%)
		Solcar 3. /evidence=ECO:0000255|PROSITE-ProRule:PRU00282	222..306		18/97 (19%)