DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment PMP34 and ALLC

DIOPT Version :9

Sequence 1:	NP_001246615.1	Gene:	PMP34 / 38532	FlyBaseID:	FBgn0052250	Length:	314	Species:	Drosophila melanogaster
Sequence 2:	XP_016859984.1	Gene:	ALLC / 55821	HGNCID:	17377	Length:	459	Species:	Homo sapiens

Alignment Length:	187	Identity:	36/187 - (19%)
Similarity:	70/187 - (37%)	Gaps:	54/187 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 AP--SKLSQVLSYQNFVHAVSGAAGGCIAMST---FYPLDT-VRS------RLQLEEAG---DVR 52
            ||  .:|::.|.:...:...|.:.||.|..:|   |.|.:. ::|      ..:..|.|   |..
Human    53 APKEGRLTRFLDFTQLMDMASESVGGKILFATDDFFAPAENLIKSDSPCFKEHEYTEFGKWMDGW 117

  Fly    53 STRQVIKEI------VLGEGFQSLYRGLGPVLQSLCISNFVYFYTFH-ALKA------------- 97
            .||:  |.|      ||..|.|.:.||.     .:.:|.|...|... :::|
Human   118 ETRR--KRIPGHDWCVLRLGIQGVIRGF-----DVDVSYFTGDYAPRVSIQAANLEEDKLPEIPE 175

  Fly    98 ----VASGGSPSQHSALKDLLLGSIAGIINVLTTTP--------FWVVNTRLRMRNV 142
                ..:..:|.:..|:.:|.....:.::.:....|        :::||::.|..::
Human   176 RGTRTGAAATPEEFEAIAELKSDDWSYLVPMTELKPGNPASGHNYFLVNSQQRWTHI 232

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
PMP34	NP_001246615.1	Mito_carr	15..96	CDD:278578	24/100 (24%)
		Mito_carr	105..202	CDD:278578	6/46 (13%)
		Mito_carr	214..303	CDD:278578
ALLC	XP_016859984.1	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG4266
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900