DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment PMP34 and SCaMC

DIOPT Version :9

Sequence 1:	NP_001246615.1	Gene:	PMP34 / 38532	FlyBaseID:	FBgn0052250	Length:	314	Species:	Drosophila melanogaster
Sequence 2:	NP_729802.1	Gene:	SCaMC / 39415	FlyBaseID:	FBgn0052103	Length:	583	Species:	Drosophila melanogaster

Alignment Length:	310	Identity:	78/310 - (25%)
Similarity:	142/310 - (45%)	Gaps:	35/310 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 HAVSGAAGGCIAMSTFYPLDTVRSRLQLEEAGDVRSTRQVIKE---IVLGE-GFQSLYRGLGPVL 78
            |.|:|...|.::.:...|||.::..||      |::.|..|.|   |:|.| |.:|::||.|..:
  Fly   288 HLVAGGIAGAVSRTCTAPLDRIKVYLQ------VQTQRMGISECMHIMLNEGGSRSMWRGNGINV 346

  Fly    79 QSLCISNFVYFYTFHALKAVASGGSPS-QHSALKDLLLGSIAGIINVLTTTPFWVVNTRLRMRNV 142
            ..:.......|..:..:|.:..|...| |.|.::....|:.||.|:.....|..|:.|||.:|..
  Fly   347 LKIAPETAFKFAAYEQMKRLIRGDDGSRQMSIVERFYAGAAAGGISQTIIYPMEVLKTRLALRRT 411

  Fly   143 ---AGTSDEVNKHYKNLLEGLKYVAEKEGIAGLWSGTIPSLM-LVSNPALQFMMYEMLKRN-IMR 202
               ||.:|...|.||           :||:...:.|.:|::: ::....:...:||.|||. |..
  Fly   412 GQYAGIADAAVKIYK-----------QEGVRSFYRGYVPNILGILPYAGIDLAVYETLKRRYIAN 465

  Fly   203 FTGGEMGS-LSFFFIGAIAKAFATVLTYPLQLVQTKQRHRSKESDSK-------PSTSAGSTPRT 259
            ....|..| |.....|:.:.....:.:|||.||:|:.:.::.|:.:.       |..|:.:....
  Fly   466 HDNNEQPSFLVLLACGSTSSTLGQLCSYPLALVRTRLQAQAAETIANQKRKTQIPLKSSDAHSGE 530

  Fly   260 ESTLELMISILQHQGIRGLFRGLEAKILQTVLTAALMFMAYEKIAGTVGM 309
            |:...|...|::.:|:.||:||:....|:.:...::.::.||..:..:|:
  Fly   531 ETMTGLFRKIVRQEGLTGLYRGITPNFLKVLPAVSISYVVYEYTSRALGI 580

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
PMP34	NP_001246615.1	Mito_carr	15..96	CDD:278578	22/81 (27%)
		Mito_carr	105..202	CDD:278578	29/102 (28%)
		Mito_carr	214..303	CDD:278578	21/95 (22%)
SCaMC	NP_729802.1	FRQ1	100..247	CDD:227455
		EFh	116..176	CDD:238008
		EFh	186..242	CDD:238008
		Mito_carr	285..370	CDD:278578	23/87 (26%)
		Mito_carr	375..463	CDD:278578	27/98 (28%)
		Mito_carr	470..581	CDD:278578	25/111 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45442022
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840