Protein Alignment PMP34 and SLC25A45

DIOPT Version :10

• Sequence 1: NP_728982.1
• Gene: PMP34 / 38532
• FlyBaseID: FBgn0052250
• Length: 314
• Species: Drosophila melanogaster
• Sequence 2: NP_872362.4
• Gene: SLC25A45 / 283130
• HGNCID: 27442
• Length: 288
• Species: Homo sapiens
• Alignment Length: 296
• Identity: 65/296 - (21%)
• Similarity: 118/296 - (39%)
• Gaps: 35/296 - (11%)

  Fly    20 VSGAAGGCIAMSTFYPLDTVRSRLQLEEAGDVRSTRQVIKEIVLGEGFQSLYRGLGPVLQSLCIS 84
            |:|...|.:.:...:|.|||:.|||.:..  .|.....:.:|...|.....::|:...:.|:.:.
Human     7 VAGWISGALGLVLGHPFDTVKVRLQTQTT--YRGIVDCMVKIYRHESLLGFFKGMSFPIASIAVV 69

  Fly    85 NFVYFYTFHALKAVASGGSPSQHSA-----LKDLLLGSIAGIINVLTTTPFWVVNTRLR----MR 140
            |.|.|..:.....|.:..|..:..|     :...|.|...|.:......||.::..||:    .|
Human    70 NSVLFGVYSNTLLVLTATSHQERRAQPPSYMHIFLAGCTGGFLQAYCLAPFDLIKVRLQNQTEPR 134

  Fly   141 NVAGTSDEVNKHYKNLLEGLKYVAEKEGIAGLWSGTIPSLMLVSNP--ALQFMMYEMLKRNIMRF 203
            ...|:..   ..|:..:.....:..:||..||:.|.. :|.|...|  .:.|:.||.|.|   ::
Human   135 AQPGSPP---PRYQGPVHCAASIFREEGPRGLFRGAW-ALTLRDTPTVGIYFITYEGLCR---QY 192

  Fly   204 T--GGEMGSLSFFFIGAIAKAFATVLTYPLQLVQTKQRHRSKESDSKPSTSAGSTPRT-ESTLEL 265
            |  |....|.:....|..|...:.|...||.:::::.:            ..|...|. :..|:.
Human   193 TPEGQNPSSATVLVAGGFAGIASWVAATPLDMIKSRMQ------------MDGLRRRVYQGMLDC 245

  Fly   266 MISILQHQGIRGLFRGLEAKILQTVLTAALMFMAYE 301
            |:|.::.:|:...|||:.....:.....|:.|::||
Human   246 MVSSIRQEGLGVFFRGVTINSARAFPVNAVTFLSYE 281

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PMP34	NP_728982.1	Mito_carr	15..96	CDD:395101	18/75 (24%)
		Mito_carr	105..202	CDD:395101	24/107 (22%)
		Mito_carr	214..303	CDD:395101	18/89 (20%)
SLC25A45	NP_872362.4	Solcar 1	1..83		18/77 (23%)
		Mito_carr	2..77	CDD:395101	18/71 (25%)
		Mito_carr	95..186	CDD:395101	19/94 (20%)
		Solcar 2	97..191		23/100 (23%)
		Mito_carr	197..288	CDD:395101	19/97 (20%)
		Solcar 3	199..286		19/95 (20%)