Protein Alignment PMP34 and SLC25A25

DIOPT Version :10

• Sequence 1: NP_728982.1
• Gene: PMP34 / 38532
• FlyBaseID: FBgn0052250
• Length: 314
• Species: Drosophila melanogaster
• Sequence 2: NP_001317917.1
• Gene: SLC25A25 / 114789
• HGNCID: 20663
• Length: 515
• Species: Homo sapiens
• Alignment Length: 302
• Identity: 68/302 - (22%)
• Similarity: 139/302 - (46%)
• Gaps: 34/302 - (11%)

  Fly    18 HAVSGAAGGCIAMSTFYPLDTVRSRLQLEEA-----GDVRSTRQVIKEIVLGEGFQSLYRGLGPV 77
            |.|:|...|.::.:...|||.::..:|:..:     |.|....|:|:|    .|.:||:||.|..
Human   235 HLVAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNNMGIVGGFTQMIRE----GGARSLWRGNGIN 295

  Fly    78 LQSLCISNFVYFYTFHALKAVASGGSPSQHSALKD-LLLGSIAGIINVLTTTPFWVVNTRLRMRN 141
            :..:...:.:.|..:..:|.:.  ||..:...:.: |:.||:||.|...:..|..|:.||:.:|.
Human   296 VLKIAPESAIKFMAYEQIKRLV--GSDQETLRIHERLVAGSLAGAIAQSSIYPMEVLKTRMALRK 358

  Fly   142 VAGTSDEVNKHYKNLLEGLKYVAEKEGIAGLWSGTIPSLM-LVSNPALQFMMYEMLKRNIMR--- 202
            ..        .|..:|:..:.:..:||:|..:.|.:|::: ::....:...:||.||...::
Human   359 TG--------QYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGIDLAVYETLKNAWLQHYA 415

  Fly   203 FTGGEMGSLSFFFIGAIAKAFATVLTYPLQLVQTKQRHRSKESDSKPSTSAGSTPRTESTLELMI 267
            ....:.|.......|.::.....:.:|||.||:|:.:.:: ..:..|..:..|         |..
Human   416 VNSADPGVFVLLACGTMSSTCGQLASYPLALVRTRMQAQA-SIEGAPEVTMSS---------LFK 470

  Fly   268 SILQHQGIRGLFRGLEAKILQTVLTAALMFMAYEKIAGTVGM 309
            .||:.:|..||:|||....::.:...::.::.||.:..|:|:
Human   471 HILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLKITLGV 512

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PMP34	NP_728982.1	Mito_carr	15..96	CDD:395101	20/82 (24%)
		Mito_carr	105..202	CDD:395101	22/98 (22%)
		Mito_carr	214..303	CDD:395101	20/88 (23%)
SLC25A25	NP_001317917.1	FRQ1	49..189	CDD:444056
		PTZ00169	237..491	CDD:240302	63/277 (23%)