DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment PMP34 and slc25a36

DIOPT Version :9

Sequence 1:	NP_001246615.1	Gene:	PMP34 / 38532	FlyBaseID:	FBgn0052250	Length:	314	Species:	Drosophila melanogaster
Sequence 2:	XP_002941237.1	Gene:	slc25a36 / 100493017	XenbaseID:	XB-GENE-947525	Length:	309	Species:	Xenopus tropicalis

Alignment Length:	330	Identity:	79/330 - (23%)
Similarity:	135/330 - (40%)	Gaps:	77/330 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 VHAVSGAAGGCIAMSTFYPLDTVRSRLQLE--------------EAGDVRSTRQV-------IKE 60
            ||..:|..||.:......||:.|::|||..              ....|....:|       :|.
Frog     8 VHLFAGGCGGTVGAILTCPLEVVKTRLQSSSVTLYISEVHLNTVNGASVNRVARVSPGPLHCLKV 72

  Fly    61 IVLGEGFQSLYRGLGPVLQSLCISNFVYFYTFHALKA----VASGGSPSQHSALKDLLLGSIAGI 121
            |:..||.:||:|||||.|..:..|..:||..:.:.|.    |.:..|...|     ::....||.
Frog    73 ILQKEGPRSLFRGLGPNLVGVAPSRAIYFAAYSSCKERLNHVFAADSTQVH-----MISAGAAGF 132

  Fly   122 INVLTTTPFWVVNTRLRMRNVAGTSDEVNKHYKNL--LEGLKYVAEKEGIAGLWSGTIPSLMLVS 184
            ..:..|.|.|::.|||::       |..|:..:.:  .|.::.|.:.:|:.|.:.|...|...:|
Frog   133 TAITATNPIWLIKTRLQL-------DARNRGERRMSAFECIRKVYKTDGLKGFYRGMSASYAGIS 190

  Fly   185 NPALQFMMYEMLKRNIMR---------------FTGGEMGSLSFFFIGAIAKAFATVLTYPLQLV 234
            ...:.|::||.:||.::.               |.|       .....|.:|..||.:.||.::|
Frog   191 ETVIHFVIYESIKRKLLEQKIADEDESVKEPSDFVG-------LMLAAATSKTCATSIAYPHEVV 248

  Fly   235 QTKQRHRSKESDSKPSTSAGSTPRT-ESTLELMISILQHQGIRGLFRGLEAKILQTVLTAALMFM 298
            :|:.|..            |:..|. ..||.|   :::.:|...|:|||...:::.:...|:|..
Frog   249 RTRLREE------------GTKYRAFFQTLSL---VVKEEGYGALYRGLTTHLVRQIPNTAIMMS 298

  Fly   299 AYEKI 303
            .||.:
Frog   299 TYEVV 303

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
PMP34	NP_001246615.1	Mito_carr	15..96	CDD:278578	28/99 (28%)
		Mito_carr	105..202	CDD:278578	23/98 (23%)
		Mito_carr	214..303	CDD:278578	23/89 (26%)
slc25a36	XP_002941237.1	Mito_carr	6..111	CDD:365909	29/102 (28%)
		Mito_carr	119..208	CDD:365909	24/100 (24%)
		Mito_carr	224..309	CDD:365909	25/102 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53601
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920