DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dyl and cutl-27

DIOPT Version :9

Sequence 1:	NP_647890.2	Gene:	dyl / 38531	FlyBaseID:	FBgn0066365	Length:	611	Species:	Drosophila melanogaster
Sequence 2:	NP_502252.3	Gene:	cutl-27 / 183003	WormBaseID:	WBGene00007802	Length:	969	Species:	Caenorhabditis elegans

Alignment Length:	347	Identity:	74/347 - (21%)
Similarity:	124/347 - (35%)	Gaps:	109/347 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly    35 SAALPLE-HRAGYGPPAPIYGAPQGPLSTGATN-DVSEEAWPLASTNDSPQIKHLQVQCEKTHMR 97
            ::.||:: ...|.....||    |.||::|..: |:|                .|.:..:.....
Worm   590 TSLLPIDPELVGLEDSTPI----QLPLNSGIAHVDLS----------------RLSIAAQCLPQG 634

  Fly    98 VNIEFD----RPFYGMIFSKGFYSDPHCVHLKPGTGHLSATFEIFL-----NS-CGMTSSANHNA 152
            :||.||    ..:.|::::...: |...|.:|.     |:.|.||:     || |......|.
Worm   635 INITFDLTQNTKYTGVVYASERF-DQCRVFVKN-----SSAFSIFIPRPKHNSWCNAVELNNE-- 691

  Fly   153 AGYGAPTPSGSYVENTIIIQYDPYVQEVWDQARKLRCTWYD--FYEKAVTFRPFQVDMLHAVTAN 215
                         .:||||..:       |:......|..|  ||:.:..:.|
Worm   692 -------------MSTIIIMSN-------DRILPHDVTTKDDLFYQVSCQYNP------------ 724

  Fly   216 FLGDNLQCWMQIQVGKGPWASEVS-----------GIVKIGQTM-------TMVLAIKDDENKFD 262
              .|:.:....|.|| ||....::           .|.|.||.:       :::..:|.:.:...
Worm   725 --NDDAKVSKGIVVG-GPSPVMITKKSHIHEKISLEITKDGQMVESVFVGESLLATVKSNVSAEL 786

  Fly   263 MLVRNCVAH----DGKRAPIQLVDQNGCVVRPKIMSKFQKIKNFGPSASVVSFAYFQAFKFPDSM 323
            :.:.:|.||    .|..|.:.|: .:||.:.|.|||..:    ..||....|.:   ||:...|.
Worm   787 LRIVDCTAHRVGGTGPPASVNLI-ADGCALLPAIMSPMR----LTPSGWQSSLS---AFRIDGSE 843

  Fly   324 NVHFQCVIQVCRYN--CPEPKC 343
            .:...|:|.:|..|  ||...|
Worm   844 QIDVVCIISICDENKKCPLMAC 865

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dyl	NP_647890.2	ZP	90..345	CDD:214579	62/290 (21%)
dyl	NP_647890.2	PHA03378	<339..494	CDD:223065	2/5 (40%)
cutl-27	NP_502252.3	PAN_1	148..219	CDD:278453
		PAN_AP_HGF	235..>287	CDD:238532
		PAN_AP_HGF	313..389	CDD:238532
		PAN_1	423..493	CDD:278453
		ZP	629..867	CDD:214579	62/288 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910