DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment dyl and cut-6

DIOPT Version :9

Sequence 1:	NP_647890.2	Gene:	dyl / 38531	FlyBaseID:	FBgn0066365	Length:	611	Species:	Drosophila melanogaster
Sequence 2:	NP_499400.2	Gene:	cut-6 / 176520	WormBaseID:	WBGene00000853	Length:	572	Species:	Caenorhabditis elegans

Alignment Length:	310	Identity:	78/310 - (25%)
Similarity:	117/310 - (37%)	Gaps:	74/310 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    73 WPLASTNDSPQIKHLQVQCEKTHMRVNIEFDRPFYGMIFSKGFYSDPHCVHLKPGTGHLSATFEI 137
            |.:..|...|...  ::.|....:.|.....:||.|.:|....|.|..|          .|..|.
Worm   218 WSMCKTEFRPGTP--EIICGPDRIGVKASTKQPFEGNVFVMDHYHDEEC----------RAGPEK 270

  Fly   138 F--LNSCGMT---SSAN-HNAAGYGAPTPSGSYVENTIIIQYDPYVQEVWDQARKLRCTWYDFY- 195
            |  ..|.|:|   |:.| |.   |.:..|.|.:||.:|:..:........||..|::|    ||
Worm   271 FPDSRSIGLTVPFSACNVHR---YRSLNPKGIFVEVSIVFMFHSLFMTKTDQTVKVQC----FYM 328

  Fly   196 --EKAVTFRPFQVDMLHAVTANFLGDNLQCWMQIQVG--KGP--------------W-ASEVSGI 241
              :|.||. |..|.|:..|....:....||...::.|  .||              | ..||.|.
Worm   329 EADKHVTV-PLSVSMITTVFREQIYQMPQCAYTLRKGAPDGPIVRFATLGESVYHRWECIEVEGA 392

  Fly   242 VKIGQTMTMVLAIKDDENKFDMLVRNCVAHDGKRAPIQLVDQNGCVVRPKIMSKFQKIKNFGPSA 306
                           |::.|.|||.:|...:|....:.::|.|||.:...::|    ..::..|.
Worm   393 ---------------DKDTFGMLVHSCYVDNGYGDRVDILDSNGCGLDAVLLS----TPDYDTSL 438

  Fly   307 SVVSFAYFQAFKFPDSMNVHFQCVIQVC-RYN--C----PEPKCGPGLPG 349
            .:.:..| ..||:.|...:.|||.|.:| :|:  |    |...| ..|||
Worm   439 RLATKPY-HVFKYADRPVLQFQCQITLCLKYDGGCEGITPPQNC-KKLPG 486

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dyl	NP_647890.2	ZP	90..345	CDD:214579	72/287 (25%)
dyl	NP_647890.2	PHA03378	<339..494	CDD:223065	5/11 (45%)
cut-6	NP_499400.2	VWA	48..208	CDD:395045
cut-6	NP_499400.2	ZP	233..480	CDD:214579	71/284 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_107918
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X161
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.810