DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment dyl and dpy-1

DIOPT Version :9

Sequence 1:	NP_647890.2	Gene:	dyl / 38531	FlyBaseID:	FBgn0066365	Length:	611	Species:	Drosophila melanogaster
Sequence 2:	NP_001370799.1	Gene:	dpy-1 / 175342	WormBaseID:	WBGene00001063	Length:	1427	Species:	Caenorhabditis elegans

Alignment Length:	288	Identity:	61/288 - (21%)
Similarity:	106/288 - (36%)	Gaps:	45/288 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    76 ASTNDSPQIKHLQVQCEKTHMRVNIEFDRPFYGMIFSKGFYSDPHCVHLKPGTGHLSATFEIFL- 139
            |.|.::..|  :.::|.....:|.:.....|.|:...||:..|..|    ..|...|....:|:
Worm  1038 AETAENSGI--IDLECVGDGFKVQVNPPAGFRGVAVVKGYQDDARC----KATASSSLPLNLFIS 1096

  Fly   140 -NSCGMTSSANHNAAGYGAPTPSGSYVENTIIIQYDPYVQEVWDQARKLRCTWYDFYEKAVTFRP 203
             |.||:|...:.:        |:|......:.:.:|..:....|:|..|:|......:.||....
Worm  1097 NNECGVTQVKSSD--------PNGLNSSLVLHLLHDDELNTAEDRAYLLQCFIGAQNQDAVVSTN 1153

  Fly   204 FQV---DMLHAVTANFLGDNLQCWMQIQVGKGPWASEVSGIVKIGQTM--------TMVLAIKDD 257
            ..|   ::..|.|.:.......|...|: .:||....||..| :|||:        |     .|.
Worm  1154 LNVVRSELAIAETISLSTLPPTCTYSIR-KEGPEGPIVSRAV-VGQTVWHRWECDGT-----NDT 1211

  Fly   258 ENKFDMLVRNCVAHDGKRAPIQLVDQNGCVVRPKIMSKFQKIKNFGPSASVVSFAYFQAFKFPDS 322
            ...:.:.|.:|.|.|........||..||.....:::......:     |:.::|....|...|:
Worm  1212 NQAYGIQVHSCYASDDVERKFAFVDPRGCSSDLALLTDLTYADD-----SLTAWAASHVFNVHDA 1271

  Fly   323 MNVHFQCVIQVCRYN---C---PEPKCG 344
            .::.|.|.:.:|..:   |   ..|.||
Worm  1272 ESLKFVCKLSLCTRDGDGCEGVTPPACG 1299

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dyl	NP_647890.2	ZP	90..345	CDD:214579	58/274 (21%)
dyl	NP_647890.2	PHA03378	<339..494	CDD:223065	3/6 (50%)
dpy-1	NP_001370799.1	VWA	823..975	CDD:395045
dpy-1	NP_001370799.1	Zona_pellucida	1050..1299	CDD:421542	56/272 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	82	1.000	Domainoid score	I5383
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_107918
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.810