DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dyl and noah-1

DIOPT Version :9

Sequence 1:	NP_647890.2	Gene:	dyl / 38531	FlyBaseID:	FBgn0066365	Length:	611	Species:	Drosophila melanogaster
Sequence 2:	NP_001250022.1	Gene:	noah-1 / 172261	WormBaseID:	WBGene00016422	Length:	1052	Species:	Caenorhabditis elegans

Alignment Length:	395	Identity:	80/395 - (20%)
Similarity:	131/395 - (33%)	Gaps:	155/395 - (39%)

- Green bases have known domain annotations that are detailed below.

  Fly    41 EHRAGYGPPAPIYGAPQGPLSTGATNDVSEEAWPLASTNDSPQIKHLQVQCEKTHMRVNIEFDRP 105
            |||.          ||:..:..|...:|..||              :|..|....::|.|....|
Worm   610 EHRR----------APESTVPIGPPVEVKAEA--------------IQTICNYEGIKVQINNGEP 650

  Fly   106 FYGMIFSKGFYSD-----------------PHCVHLKP---------GTGH----------LSAT 134
            |.|:||.|..:..                 |....::|         .||.          |...
Worm   651 FSGVIFVKNKFDTCRVEVANSNAATLVLGLPKDFGMRPISLDNIDDNETGKNKTKKGEETPLKDE 715

  Fly   135 FEIF--------LNSCGMTSSANHNAAGYGAPTPSGSYVENTIIIQYD----PYVQEVWDQARKL 187
            .|.|        ...||:....|            |:| ::|::||.:    |.:....||..::
Worm   716 IEEFRQKRQAAEFRDCGLVDLLN------------GTY-KSTVVIQTNNLGIPGLVTSMDQLYEV 767

  Fly   188 RCTWYDFYEKAVTFRPFQVDMLHAVTANFLGDNLQCWMQIQVGKGPWASEVS--GIVKIGQTMTM 250
            .|.:                      ::.||..:|....:.| .||.|:.:.  |.:::|..:.|
Worm   768 SCDY----------------------SSMLGGRVQAGYNMTV-TGPEANLIQPRGKIELGNPVLM 809

  Fly   251 -------------------VLAIK------DDENKFDMLVRNCVAHDGKRA-------PIQLVDQ 283
                               :|.::      |||  .|..|:||.|..|...       .::|:|
Worm   810 QLLNGDGTEQPLVQAKLGDILELRWEIMAMDDE--LDFFVKNCHAEPGVAGGKAGAGEKLRLID- 871

  Fly   284 NGC---VVRPKIMSKFQKIKNFGPSASVVSFAYFQAFKFPDSMNVHFQCVIQVCRYNCPEPKCGP 345
            .||   .|..|::....:||     :|.|.....|||:|..|.::...|.:::|:.:|...:|
Worm   872 GGCPTPAVAQKLIPGAIEIK-----SSAVKTTKMQAFRFDSSASIRVTCEVEICKGDCEPVEC-- 929

  Fly   346 GLPGG 350
            .|.||
Worm   930 ALTGG 934

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dyl	NP_647890.2	ZP	90..345	CDD:214579	67/339 (20%)
dyl	NP_647890.2	PHA03378	<339..494	CDD:223065	4/12 (33%)
noah-1	NP_001250022.1	PAN_AP_HGF	107..189	CDD:238532
		PAN_AP_HGF	201..282	CDD:238532
		PAN_AP_HGF	295..379	CDD:238532
		PAN_AP_HGF	391..473	CDD:238532
		PAN_APPLE	485..557	CDD:294081
		Zona_pellucida	<818..920	CDD:278526	26/109 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910