DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dyl and Matn2

DIOPT Version :9

Sequence 1:	NP_647890.2	Gene:	dyl / 38531	FlyBaseID:	FBgn0066365	Length:	611	Species:	Drosophila melanogaster
Sequence 2:	NP_001345709.1	Gene:	Matn2 / 17181	MGIID:	109613	Length:	956	Species:	Mus musculus

Alignment Length:	185	Identity:	39/185 - (21%)
Similarity:	57/185 - (30%)	Gaps:	65/185 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 VLNTQHLSVHGDASHIESAALPLEHRAGYGPPAPIYGAPQGPLSTGATNDV------------SE 70
            |.|...|......|.:|.|...:.|                 ||||....:            :|
Mouse   105 VKNEFSLKTFKRKSEVERAVKRMRH-----------------LSTGTMTGLAIQYALNIAFSEAE 152

  Fly    71 EAWPLAS---------TNDSPQIKHLQVQCEKTHMRVNIEFDRPFYGMIFS-----------KGF 115
            .|.||..         |:..||....:|..:..:..:          :||:           |..
Mouse   153 GARPLRENVPRIIMIVTDGRPQDSVAEVAAKARNTGI----------LIFAIGVGQVDLNTLKAI 207

  Fly   116 YSDPHCVH--LKPGTGHLSATFEIFLN---SCGMTSSANHNAAGYGAPTPSGSYV 165
            .|:||..|  |......:.:...:|.|   :..|.|...||.|.:...|| |||:
Mouse   208 GSEPHKDHVFLVANFSQIESLTSVFQNKLCTVHMCSVLEHNCAHFCLNTP-GSYI 261

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dyl	NP_647890.2	ZP	90..345	CDD:214579	20/92 (22%)
dyl	NP_647890.2	PHA03378	<339..494	CDD:223065
Matn2	NP_001345709.1	vWA_Matrilin	54..276	CDD:238752	39/185 (21%)
		FXa_inhibition	283..318	CDD:317114
		FXa_inhibition	324..359	CDD:317114
		FXa_inhibition	365..400	CDD:317114
		FXa_inhibition	406..441	CDD:317114
		vWFA	<438..481	CDD:320736
		FXa_inhibition	488..523	CDD:317114
		vWFA	<520..563	CDD:320736
		FXa_inhibition	570..605	CDD:317114
		vWFA	<602..644	CDD:320736
		vWFA	652..892	CDD:320736
		Matrilin_ccoil	911..953	CDD:313592
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910