DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dyl and AgaP_AGAP003012

DIOPT Version :9

Sequence 1:	NP_647890.2	Gene:	dyl / 38531	FlyBaseID:	FBgn0066365	Length:	611	Species:	Drosophila melanogaster
Sequence 2:	XP_311867.4	Gene:	AgaP_AGAP003012 / 1272942	VectorBaseID:	AGAP003012	Length:	695	Species:	Anopheles gambiae

Alignment Length:	382	Identity:	89/382 - (23%)
Similarity:	143/382 - (37%)	Gaps:	117/382 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly    32 HIESAALPLEHRAGYGP--------PAPIYGAPQGPLSTGATNDVSEEA---WPLA-STNDSPQI 84
            |::..:||      .||        |....|.|.|..........|.:|   .|:. .|.:.|.:
Mosquito   280 HLDHKSLP------DGPSTYLNGERPLIDVGEPSGDYFENICEKQSNQAENTLPVVFDTVEDPAV 338

  Fly    85 KHL----------------QVQCEKTHMRVNIEFDRPFYGMIFSKGFYSDPHCVHLKPGTGHL-- 131
            .:|                .|.|:.|.:.|.:..::||.|.|::.|          :..|.::
Mosquito   339 NNLTRNDANCDKTGTCYDVSVHCKDTRIAVQVRTNKPFNGRIYALG----------RSETCNIDV 393

  Fly   132 --SATFEIFLNSCGM---TSSANHNAAGYGAPTPSGSYVENTIIIQYDPYVQEVWDQARKLRCTW 191
              |.||.:.|...|.   |.||            :|.| .||:::|:...|....|:..|::||
Mosquito   394 INSDTFRLDLTMGGQDCNTQSA------------TGIY-SNTVVLQHHSVVMTKADKIYKVKCT- 444

  Fly   192 YDFYEKAVTFRPFQV---DMLHAVTANFLGDNLQCWMQIQVGKGP------------WASEVSGI 241
            ||...|.::|....:   :|:|                  :...|            .|.||. .
Mosquito   445 YDMSSKNISFGMLPIRDPEMIH------------------INSSPEAPPPRIRILDARAREVE-T 490

  Fly   242 VKIGQTMTMVLAIKDDENKFDMLVRNCV--AHDGKRAPIQLVDQNGCVVRPKIMSKFQKIKNFGP 304
            |:||..:|..:.|.:| ..:.:..|:||  |.|.| :..|::|.:||.|.|.|...|.:..|...
Mosquito   491 VRIGDRLTFRIEIPED-TPYGIFARSCVAMAKDSK-STFQIIDDDGCPVDPTIFPAFTQDGNALQ 553

  Fly   305 SASVVSFAYFQAFKFPDSMNVHFQCVIQVCRYNCPEPKCGPGLPGGEYGLPQIGANG 361
            |       .::||:|.:|..|.|||.::.|...|....|       |:|...:.:.|
Mosquito   554 S-------IYEAFRFTESYGVIFQCNVKYCLGPCEPAVC-------EWGRDSVESWG 596

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dyl	NP_647890.2	ZP	90..345	CDD:214579	70/278 (25%)
dyl	NP_647890.2	PHA03378	<339..494	CDD:223065	4/23 (17%)
AgaP_AGAP003012	XP_311867.4	PAN_4	35..86	CDD:290993
		PAN_AP_HGF	119..199	CDD:238532
		PAN_1	224..315	CDD:278453	9/40 (23%)
		ZP	360..576	CDD:214579	67/267 (25%)
		Zona_pellucida	<490..583	CDD:278526	32/101 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X161
TreeFam	0	0.000	Not matched by this tool.
	2	1.910