DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dyl and AgaP_AGAP003261

DIOPT Version :9

Sequence 1:	NP_647890.2	Gene:	dyl / 38531	FlyBaseID:	FBgn0066365	Length:	611	Species:	Drosophila melanogaster
Sequence 2:	XP_307770.5	Gene:	AgaP_AGAP003261 / 1269166	VectorBaseID:	AGAP003261	Length:	1737	Species:	Anopheles gambiae

Alignment Length:	525	Identity:	135/525 - (25%)
Similarity:	222/525 - (42%)	Gaps:	109/525 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    50 APIYGAPQGPLS-TGATNDVSEEAWPLASTNDSPQIKHLQVQC-EKTHMRVNIEFDRPFYGMIFS 112
            |.::|..|..|: .|...:|..:....|..:|...|:.:.|:| :::.|.|.|:|:..|.|:|:|
Mosquito    15 AQLFGDSQNALAPAGNRRNVLRQGDRAAGGHDHTHIETIDVKCDQRSGMLVTIQFEDDFQGVIYS 79

  Fly   113 KGFYSDPHCVHLKPGTGHLSATFEIFLNSCGMTSSANHNAAGYGAPTPSGSYVENTIIIQYDPYV 177
            :|:::||.|.:::...|....||.:..:.||...|....|:           |:|.::||.|..|
Mosquito    80 QGYHNDPKCRYVQANQGGRQFTFTVPYDRCGSKPSCAVCAS-----------VDNVLVIQTDEEV 133

  Fly   178 QEVWDQARKLRCTWYDFYEKAVTFRPFQVDMLHAVTANFLGDNLQCWMQIQVGKGPWASEVSGIV 242
            ||.||.||::.|:..:..:..:.|:||.||.|..|........::|||.||.|..|..|.:..|:
Mosquito   134 QEAWDTARRISCSQSEQQQNTIIFKPFVVDQLEVVNVPTSTGGVECWMDIQRGTYPSISPIPSII 198

  Fly   243 KIGQTMTMVLAIKDDENKFDMLVRNCVAHD------GKRAPIQLVDQNGCVVRPKIMSKFQKIKN 301
            |||:.:::::.::|.:.::|:.|::|.|.|      ...|.:||.|:|||..:.|:...:||...
Mosquito   199 KIGEALSVLVYLRDPKGEYDVSVKDCYAFDSPDYEAATTARLQLSDKNGCSRKKKLFGLWQKTTQ 263

  Fly   302 FGPS-ASVVSFAYFQAFKFPDSMNVHFQCVIQVCRYNCPEPKCGP------------------GL 347
            .|.| |::|.....:||||||.|.|..:|.|::||..|....|..                  |.
Mosquito   264 TGSSGATLVVHNSIKAFKFPDRMQVFLKCDIEICRGGCGPQVCAEENLISTVETTTKRPSPTRGR 328

  Fly   348 PGGEYGL----------PQIGANGLSEEY------------GPPEAYERNDFALGGPGVLPPAAY 390
            |.....|          |.:.|.....:|            .||...|..      |...||...
Mosquito   329 PTQTTSLAPVVPTRGRRPSVTAAPTQPQYTEPATQPPRRGTRPPRPVETT------PATAPPRRT 387

  Fly   391 PDP------RHPASD---ATGAYSENQPDVVPSPQAQTSAAVPTADSGTVSGPASSQSPQPQPT- 445
            ..|      |.|.::   |.|:..:...||:.:.:       |....|:......|:..:|.||
Mosquito   388 RPPNTRAPTRAPTTEFTCAPGSTDDRCNDVIVTQR-------PDCSRGSRDPRCRSRGTRPTPTT 445

  Fly   446 ------------GSNELGLP-----------PPPLPGQSGQYS--TVKRKDDLSAGGNLVSLGGR 485
                        ||.:...|           |||.| .:.::|  ||:.:::..:..|.:.....
Mosquito   446 TEVTPAPLRCFPGSTDPRCPTTFRPSVRPTRPPPSP-TTPRFSTTTVEEEEEDDSVPNCLLRSND 509

  Fly   486 PRSVE 490
            ||..|
Mosquito   510 PRCEE 514

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dyl	NP_647890.2	ZP	90..345	CDD:214579	86/262 (33%)
dyl	NP_647890.2	PHA03378	<339..494	CDD:223065	40/227 (18%)
AgaP_AGAP003261	XP_307770.5	ZP	56..306	CDD:214579	85/260 (33%)
AgaP_AGAP003261	XP_307770.5	Zona_pellucida	<200..298	CDD:278526	32/97 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0005923
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910