DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Fdx2 and FDX1

DIOPT Version :9

Sequence 1:	NP_647889.2	Gene:	Fdx2 / 38530	FlyBaseID:	FBgn0035529	Length:	152	Species:	Drosophila melanogaster
Sequence 2:	NP_004100.1	Gene:	FDX1 / 2230	HGNCID:	3638	Length:	184	Species:	Homo sapiens

Alignment Length:	149	Identity:	80/149 - (53%)
Similarity:	100/149 - (67%)	Gaps:	10/149 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 RAASRLALRSLNLRSPIATRTFSTGLAL------KTKDVVNITFVRANGDKIKTSGKVGDSLLDV 66
            ||.|...||:   |.|..:...|..|::      .::|.:.:.|:..:|:.:.|.||||||||||
Human    31 RAGSSGLLRN---RGPGGSAEASRSLSVSARARSSSEDKITVHFINRDGETLTTKGKVGDSLLDV 92

  Fly    67 VVNNNVDLDGFGACEGTLTCSTCHLIFKTSDFEKLPDKPGDEELDMLDLAYELTDTSRLGCQITL 131
            ||.||:|:||||||||||.||||||||:...:||| |...|||.|||||||.|||.|||||||.|
Human    93 VVENNLDIDGFGACEGTLACSTCHLIFEDHIYEKL-DAITDEENDMLDLAYGLTDRSRLGCQICL 156

  Fly   132 SKDMEGLEVHVPSTINDAR 150
            :|.|:.:.|.||.|:.|||
Human   157 TKSMDNMTVRVPETVADAR 175

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Fdx2	NP_647889.2	fer2	41..144	CDD:412190	65/102 (64%)
FDX1	NP_004100.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	35..57		6/24 (25%)
FDX1	NP_004100.1	fer2	67..168	CDD:320788	64/101 (63%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	119	1.000	Domainoid score	I5817
eggNOG	1	0.900	-	-		E1_COG0633
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H31216
Inparanoid	1	1.050	147	1.000	Inparanoid score	I4421
Isobase	1	0.950	-	0	Normalized mean entropy	S1416
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1380051at2759
OrthoFinder	1	1.000	-	-		FOG0006407
OrthoInspector	1	1.000	-	-		oto90956
orthoMCL	1	0.900	-	-		OOG6_100695
Panther	1	1.100	-	-	LDO	PTHR23426
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R421
SonicParanoid	1	1.000	-	-		X4080
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	15	14.810