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Protein Alignment Hexo1 and Hexa

DIOPT Version :9

Sequence 1:	NP_523924.1	Gene:	Hexo1 / 38528	FlyBaseID:	FBgn0041630	Length:	622	Species:	Drosophila melanogaster
Sequence 2:	NP_001004443.1	Gene:	Hexa / 300757	RGDID:	2792	Length:	528	Species:	Rattus norvegicus

Alignment Length:	579	Identity:	175/579 - (30%)
Similarity:	267/579 - (46%)	Gaps:	96/579 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    58 CRLFCGSSIG--------TLWPKPTGTVRLDTLMRQVDISFIDFNFN---GIARQ------QKLW 105
            |||:....:.        .|||.|.   .:.|..|:..:...:|.|.   |.|.|      .:.:
  Rat     4 CRLWVSLLLAAALACLATALWPWPQ---YIQTSHRRYTLYPNNFQFRYHAGSAAQAGCVVLDEAF 65

  Fly   106 RAVEDRFMNML--EAQIP----DRKVLARGGYRMSVNINTPD-EPTPARLTLDTDESYTLDIDTD 163
            |    |:.::|  ....|    .:|....|...:.|::.|.: ...|   .|::.|:|||.|:.|
  Rat    66 R----RYRSLLFGSGSWPRPSFSKKQQPLGKNILMVSVVTAECNEFP---NLESVENYTLTINDD 123

  Fly   164 ASGHVLANITASNFFGARHGLETLAQLIVYDDIRREVQVTANAT-INDAPVYKWRGLLLDTSRNY 227
            .     ..:::...:||..||||.:||:...   .|.....|.| |.|.|.:..||:||||||:|
  Rat   124 Q-----CLLSSETVWGALRGLETFSQLVWKS---AEGTFFINKTKITDFPRFPHRGILLDTSRHY 180

  Fly   228 YSVKSIKRTLEGMALVKLNTFHWHITDSHSFPLEVKKRPELHKLGAYSQ-RQVYTRRDVAEVVEY 291
            ..:.||..||:.||..|.|.||||:.|..|||.|....|||.:.|:::. ..:||.:||.||:||
  Rat   181 LPLSSILNTLDVMAYNKFNVFHWHLVDDSSFPYESFTFPELTRKGSFNPVTHIYTAQDVKEVIEY 245

  Fly   292 GRVRGIRVMPEFDAPAHV---GEGWQHKNMTACFNAQPWKSFCVEPPCGQLDPTVNEMYDVLEDI 353
            .|:|||||:.|||.|.|.   |.|.... :|.|::...     :....|.::|::|..||.:...
  Rat   246 ARLRGIRVLAEFDTPGHTLSWGAGVPGL-LTPCYSGSR-----LSGTYGPVNPSLNSTYDFMSTF 304

  Fly   354 YGTMFDQFNPDIF-HMGGDEVSTSCWNSSQPIQQWMKKQGWGLETADFMRLWGHFQTEALGRVDK 417
            :..:...| ||.: |:|||||..:||.|:..||.:|||:|:    .|:.:|...:....|..|..
  Rat   305 FLEISSVF-PDFYLHLGGDEVDFTCWKSNPNIQAFMKKKGF----TDYKQLESFYIQTLLDIVSD 364

  Fly   418 VANGTHTPIILWTSGLTEEPFIDEY-LNPERYIIQIWTTGVD----PKVKKILERGYKIIVSNYD 477
            ...|    .::|     :|.|.::. :.|:. |||:|...:.    .:::.|.:.|::.::|
  Rat   365 YDKG----YVVW-----QEVFDNKVKVRPDT-IIQVWREEMPVQYMKEIEAITQAGFRALLS--- 416

  Fly   478 ALYLDCGGAGW----VTDGNNWCSPYIGWQKVYDNSLKSIAGDYEHHVLGAEGAIWSEQIDEHTL 538
                    |.|    |..|.:|...|    ||...:.:..... :..|:|.|..:|.|.:|...|
  Rat   417 --------APWYLNRVKYGPDWKEMY----KVEPLAFRGTPAQ-KALVIGGEACMWGEYVDSTNL 468

  Fly   539 DNRFWPRASALAERLW-SNPAEGWRQAESRLLLHRQRLVDNGLGAEAMQPQWCLQN-EH 595
            ..|.||||.|:||||| ||.......|..||...|..|:..|:.|:.:...:|.|. ||
  Rat   469 VPRLWPRAGAIAERLWSSNLTTNMDFAFKRLSHFRCELLRRGIQAQPISVGYCEQEFEH 527

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.