Protein Alignment Hexo1 and hex-1

DIOPT Version :10

• Sequence 1: NP_523924.1
• Gene: Hexo1 / 38528
• FlyBaseID: FBgn0041630
• Length: 622
• Species: Drosophila melanogaster
• Sequence 2: NP_508409.1
• Gene: hex-1 / 180533
• WormBaseID: WBGene00020509
• Length: 555
• Species: Caenorhabditis elegans
• Alignment Length: 577
• Identity: 181/577 - (31%)
• Similarity: 273/577 - (47%)
• Gaps: 103/577 - (17%)

  Fly    65 SIGTLWPKP--------TGTVRLDTLMRQVDISFIDFNFNGIARQQKLWRAVEDRFMNMLEAQIP 121
            |:|.:||.|        ..|:..|.:  .:|:        |..:...:..::.|.:||......|
 Worm    30 SVGGVWPLPKKIVYGSKNRTITYDKI--GIDL--------GDKKDCDILLSMADNYMNKWLFPFP 84

  Fly   122 DRKVLARGGYR-MSVNINTPDEPTPARLTLDTDESYTLDID-TDASGHVLANITASNFFGARHGL 184
            ..  :..||.. ..:.:...||...........|.|.|.:. |:|.      |.|...:||...:
 Worm    85 VE--MKTGGTEDFIITVTVKDECPSGPPVHGASEEYLLRVSLTEAV------INAQTVWGALRAM 141

  Fly   185 ETLAQLIVYDDIRREVQVTANATINDAPVYKWRGLLLDTSRNYYSVKSIKRTLEGMALVKLNTFH 249
            |:|:.|:.||...:|.|: ....|.|.|.:..||:::|:||::.||..|||.||.|::.|||..|
 Worm   142 ESLSHLVFYDHKSQEYQI-RTVEIFDKPRFPVRGIMIDSSRHFLSVNVIKRQLEIMSMNKLNVLH 205

  Fly   250 WHITDSHSFPLEVKKRPELHKLGAYSQRQVYTRRDVAEVVEYGRVRGIRVMPEFDAPAHVGEGWQ 314
            ||:.||.|||....|.||||.:||||.|.||:|.|:|:|:.:.|:|||||:||||.|.|. ..|:
 Worm   206 WHLVDSESFPYTSVKFPELHGVGAYSPRHVYSREDIADVIAFARLRGIRVIPEFDLPGHT-SSWR 269

  Fly   315 HKN--MTACFNAQPWKSFCVEPPCGQLDPTVNE-----MYDVLEDIYGTMFDQFNPDIFHMGGDE 372
            .:.  :|.||:.:..::|..    ..:|| :||     :.:.||::..|..|||    .|:||||
 Worm   270 GRKGFLTECFDEKGVETFLP----NLVDP-MNEANFDFISEFLEEVTETFPDQF----LHLGGDE 325

  Fly   373 VS---TSCWNSSQPIQQWMKKQGWGLETADFMRLWGHFQTEALGRVDKVANGTHTPIILWTSGLT 434
            ||   ..||..::.|:::|:::|:|.:|.    |..::..|.|.::.:.......| |.|
 Worm   326 VSDYIVECWERNKKIRKFMEEKGFGNDTV----LLENYFFEKLYKIVENLKLKRKP-IFW----- 380

  Fly   435 EEPFIDEYLNPERYIIQIWTTG----VDPKVKKILERGYKIIVS-----NYDALYLDCGGAGW-- 488
            :|.|.:...:|.. :|.||...    :..:||.|..:.:.:|||     ||...     ||.|
 Worm   381 QEVFDNNIPDPNA-VIHIWKGNTHEEIYEQVKNITSQNFPVIVSACWYLNYIKY-----GADWRD 439

  Fly   489 ----VTDGNN---WCSPYIGWQKVYDNSLKSIAGDYEHHVLGAEGAIWSEQIDEHTLDNRFWPRA 546
                ....|:   :|.|        .|...::|  .:..|.|...|||.|.:|...::.|.||||
 Worm   440 EIRGTAPSNSRYYYCDP--------TNFNGTVA--QKELVWGGIAAIWGELVDNTNIEARLWPRA 494

  Fly   547 SALAERLWSNPAEGWRQAES---RLLLHRQRLVDNGLGAEAMQPQWCLQNEHECPID 600
            ||.|||||| |||..::||.   |:...|.|||..|.   .:||.   .|...||.:
 Worm   495 SAAAERLWS-PAEKTQRAEDAWPRMHELRCRLVSRGY---RIQPN---NNPDYCPFE 544

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hexo1	NP_523924.1	Glycohydro_20b2	69..190	CDD:434261	26/130 (20%)
		GH20_HexA_HexB-like	214..579	CDD:119332	139/395 (35%)
hex-1	NP_508409.1	Glyco_hydro_20b	34..147	CDD:446174	26/130 (20%)
		GH20_HexA_HexB-like	170..529	CDD:119332	139/395 (35%)