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Protein Alignment Hexo1 and Hexa

DIOPT Version :10

Sequence 1:	NP_523924.1	Gene:	Hexo1 / 38528	FlyBaseID:	FBgn0041630	Length:	622	Species:	Drosophila melanogaster
Sequence 2:	NP_034551.2	Gene:	Hexa / 15211	MGIID:	96073	Length:	528	Species:	Mus musculus

Alignment Length:	573	Identity:	176/573 - (30%)
Similarity:	264/573 - (46%)	Gaps:	91/573 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    58 CRLFCGSSIG--------TLWPKPTGTVRLDTLMRQVDISFIDFNFN---------GIARQQKLW 105
            |||:....:.        .|||.|.   .:.|..|:..:...:|.|.         |.....:.:
Mouse     4 CRLWVSLLLAAALACLATALWPWPQ---YIQTYHRRYTLYPNNFQFRYHVSSAAQAGCVVLDEAF 65

  Fly   106 RAVEDRFMNML--EAQIP----DRKVLARGGYRMSVNINTPD-EPTPARLTLDTDESYTLDIDTD 163
            |    |:.|:|  ....|    ..|....|...:.|::.|.: ...|   .|::.|:|||.|:.|
Mouse    66 R----RYRNLLFGSGSWPRPSFSNKQQTLGKNILVVSVVTAECNEFP---NLESVENYTLTINDD 123

  Fly   164 ASGHVLANITASNFFGARHGLETLAQLIVYDDIRREVQVTANAT-INDAPVYKWRGLLLDTSRNY 227
            ..  :||:.|.   :||..||||.:||:...   .|.....|.| |.|.|.:..||:||||||:|
Mouse   124 QC--LLASETV---WGALRGLETFSQLVWKS---AEGTFFINKTKIKDFPRFPHRGVLLDTSRHY 180

  Fly   228 YSVKSIKRTLEGMALVKLNTFHWHITDSHSFPLEVKKRPELHKLGAYSQ-RQVYTRRDVAEVVEY 291
            ..:.||..||:.||..|.|.||||:.|..|||.|....|||.:.|:::. ..:||.:||.||:||
Mouse   181 LPLSSILDTLDVMAYNKFNVFHWHLVDDSSFPYESFTFPELTRKGSFNPVTHIYTAQDVKEVIEY 245

  Fly   292 GRVRGIRVMPEFDAPAHV---GEGWQHKNMTACFNAQPWKSFCVEPPCGQLDPTVNEMYDVLEDI 353
            .|:|||||:.|||.|.|.   |.| ....:|.|::...     :....|.::|::|..||.:..:
Mouse   246 ARLRGIRVLAEFDTPGHTLSWGPG-APGLLTPCYSGSH-----LSGTFGPVNPSLNSTYDFMSTL 304

  Fly   354 YGTMFDQFNPDIF-HMGGDEVSTSCWNSSQPIQQWMKKQGWGLETADFMRLWGHFQTEALGRVDK 417
            :..:...| ||.: |:|||||..:||.|:..||.:|||:|:    .||.:|...:....|..|..
Mouse   305 FLEISSVF-PDFYLHLGGDEVDFTCWKSNPNIQAFMKKKGF----TDFKQLESFYIQTLLDIVSD 364

  Fly   418 VANGTHTPIILWTSGLTEEPFIDEY-LNPERYIIQIWTTGVDP----KVKKILERGYKIIVSNYD 477
            ...|    .::|     :|.|.::. :.|:. |||:|...:..    :::.|...|::.::|
Mouse   365 YDKG----YVVW-----QEVFDNKVKVRPDT-IIQVWREEMPVEYMLEMQDITRAGFRALLS--- 416

  Fly   478 ALYLDCGGAGWVTDGNNWCSPYIGWQKVYDNSLKSIAGDYEHH--VLGAEGAIWSEQIDEHTLDN 540
                    |.|..:...: .|  .|:.:|.....:..|..|..  |:|.|..:|.|.:|...|..
Mouse   417 --------APWYLNRVKY-GP--DWKDMYKVEPLAFHGTPEQKALVIGGEACMWGEYVDSTNLVP 470

  Fly   541 RFWPRASALAERLW-SNPAEGWRQAESRLLLHRQRLVDNGLGAEAMQPQWCLQ 592
            |.||||.|:||||| ||.......|..||...|..||..|:.|:.:...:|.|
Mouse   471 RLWPRAGAVAERLWSSNLTTNIDFAFKRLSHFRCELVRRGIQAQPISVGYCEQ 523

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 592.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.