Protein Alignment Hexo1 and Hexo2

DIOPT Version :10

• Sequence 1: NP_523924.1
• Gene: Hexo1 / 38528
• FlyBaseID: FBgn0041630
• Length: 622
• Species: Drosophila melanogaster
• Sequence 2: XP_061506877.1
• Gene: Hexo2 / 1268907
• VectorBaseID: AGAMI1_003439
• Length: 605
• Species: Anopheles gambiae
• Alignment Length: 614
• Identity: 235/614 - (38%)
• Similarity: 332/614 - (54%)
• Gaps: 46/614 - (7%)

  Fly    10 VALLLALVSQLAAHSSDDLVYGYEC-RSGYCQKV----ELSEENYVKAISLPVCRLFCGSSIGTL 69
            |.|:|....|.|.....|:  .|:| ....|.:|    :.:.|::|.: :|..|||.|| ..|.|
Mosquito    11 VVLVLFHAFQHAVSCLKDI--SYKCTNEEQCVRVYGNTKSASESHVFS-TLSNCRLLCG-KYGPL 71

  Fly    70 WPKPTGTVRL---DTLMRQVDISFIDFNFNGIARQQKLWRAVEDRFMNMLEAQIPDRKVLARGGY 131
            ||:|||.|.|   .|::..:::.|.....|.......:.|.::..|:..|.... ..::|.....
Mosquito    72 WPRPTGHVTLGKETTVVNPLNLRFEQDFINQTTEGTTILREIKMYFLRNLRKAF-QTQILHESTP 135

  Fly   132 RMSVNINTPDEPTPARLTLDTDESYTLDIDTDASGHVLANITASNFFGARHGLETLAQLIVYDDI 196
            .|.:.|..........|:...||||.|.|..:....|:..|.|...||.|||.|||.||  :..:
Mosquito   136 GMPIIIKIQITSNETNLSWYVDESYKLKISIENLTTVVTTIEAKTIFGTRHGFETLLQL--FTTV 198

  Fly   197 RREVQVTANATINDAPVYKWRGLLLDTSRNYYSVKSIKRTLEGMALVKLNTFHWHITDSHSFPLE 261
            ...|.:.:.|.|.|.|:|..||||:||:|||..:|.:||.::.||..|.|.|||||||:.|||::
Mosquito   199 NSSVNILSQANIIDQPIYAHRGLLIDTARNYIPIKCLKRQIDAMAASKFNVFHWHITDTQSFPMQ 263

  Fly   262 VKKRPELHKLGAYSQRQVYTRRDVAEVVEYGRVRGIRVMPEFDAPAHVGEGWQH------KNMTA 320
            ....||:...||||:.:||::.|:..:::|.:.|||||:.|.|||||.|.|||.      .|:..
Mosquito   264 FDTVPEMVFYGAYSKEEVYSQNDIKSIIKYAKYRGIRVILELDAPAHAGNGWQWGPEKDLGNLAV 328

  Fly   321 CFNAQPWKSFCVEPPCGQLDPTVNEMYDVLEDIYGTMFDQFNPD-IFHMGGDEVSTSCWNSSQPI 384
            |.|.:||::||:|||||||:|....:|.||:.||..:.:....: :.|||||||...|||::..|
Mosquito   329 CVNQKPWRNFCIEPPCGQLNPINPNLYTVLQQIYKDIAEMNKEESVIHMGGDEVFFGCWNATAEI 393

  Fly   385 QQWMKKQGWGLETADFMRLWGHFQTEALGRVDKV--ANGT---------HTPIILWTSGLTEEPF 438
            ..::.....|....||:.:|..||.:.|...|..  |||:         .:|:|||:|.||:...
Mosquito   394 INYLMDHNLGRTEQDFLTMWSKFQKKVLNLWDNARRANGSAYSASTNEHSSPVILWSSRLTDPLV 458

  Fly   439 IDEYLNPERYIIQIWTTGVDPKVKKILERGYKIIVSNYDALYLDCGGAGWVTDGNNWCSPYIGWQ 503
            ||::|:..||:||.|........|::.:.|||:|||..||.|||.|..|..|        |..|:
Mosquito   459 IDKFLSKNRYVIQTWLPSSSTIPKELQKLGYKLIVSTKDAWYLDHGFWGVTT--------YYTWK 515

  Fly   504 KVYDNSLKSIAGDYEHHVLGAEGAIWSEQIDEHTLDNRFWPRASALAERLWSNPAEGWRQAESRL 568
            |||||.|....|     :||.|..:|:|.|||:::|.|.||||:|.||||||||......||||.
Mosquito   516 KVYDNQLPKGNG-----ILGGEVCVWTEYIDEYSIDGRTWPRAAAAAERLWSNPETKAIDAESRF 575

  Fly   569 LLHRQRLVDNGLGAEAMQPQWCLQNEHEC 597
            ..||:||:..|:..||:.|:||.|||.:|
Mosquito   576 FCHRERLIIRGIQPEALAPRWCEQNEKQC 604

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hexo1	NP_523924.1	Glycohydro_20b2	69..190	CDD:434261	35/123 (28%)
		GH20_HexA_HexB-like	214..579	CDD:119332	164/382 (43%)
Hexo2	XP_061506877.1	None