Protein Alignment TfIIEbeta and gtf-2E2

DIOPT Version :10

• Sequence 1: NP_523923.1
• Gene: TfIIEbeta / 38527
• FlyBaseID: FBgn0015829
• Length: 292
• Species: Drosophila melanogaster
• Sequence 2: NP_496466.1
• Gene: gtf-2E2 / 174765
• WormBaseID: WBGene00010054
• Length: 289
• Species: Caenorhabditis elegans
• Alignment Length: 299
• Identity: 105/299 - (35%)
• Similarity: 169/299 - (56%)
• Gaps: 29/299 - (9%)

  Fly     1 MDPALLREREAFKKRAMATPTVEKKSKPDRPAPPP------PSDDSRRKMRPPNAPRLDATTYKT 59
            |||.|||:|.||:|.|..|..|:.|     |...|      .|:.::.|.:..:.|..:.:....
 Worm     1 MDPELLRQRTAFQKHAATTMAVQNK-----PTTAPNSHTTYSSEAAKAKKKKSSGPAQNLSKLPD 60

  Fly    60 MSG--------SSQYRFGVLAKIVKFMRTRHQDGDDHPLTIDEILDETNQLDIGQSVKNWLASEA 116
            .:.        |:...|..:||||.:|:.||.:....|||:.|||||....|:.:....:| .||
 Worm    61 FNNSVSNANALSNATNFSTMAKIVDYMKKRHLNNQQWPLTLQEILDELQIFDLSKRSLAFL-QEA 124

  Fly   117 LHNNPKVEASPCGTKFSFKPVYKIKDGKTLMRLLKQHDLKGLGGILLDDVQESLPHCEKVLKNRS 181
            |.|||::...  ..||:|:|.||||...:|:.:.::|...|.||||:.|:.|.:.:.:.:|:..|
 Worm   125 LPNNPRLIME--SEKFAFRPPYKIKGKTSLVAVARKHYQDGKGGILVSDLAECVANYDALLQQVS 187

  Fly   182 AEILFVVRPIDKKK--ILFYNDRTANF-SVDDEFQKLWRSATVDAMDDAKIDEYLEKQGIRSMQD 243
            :|::.|...::|||  ::||||:...| .::|:|:.|||..:||.:|:.||:|||:|:|:.:|:|
 Worm   188 SEVIVVPTQVNKKKDRVVFYNDKEFTFPELEDDFKALWRHVSVDHLDEKKIEEYLQKKGLDAMKD 252

  Fly   244 --HGLKKAIPKRKKAANKKRQFKKPRDNEHLADVLEVYE 280
              ..::...|.::|||  ||:|.:...|||:..|||.||
 Worm   253 LTPKVRMQAPLKRKAA--KRRFNQKVQNEHMDGVLEDYE 289

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TfIIEbeta	NP_523923.1	TFIIE_beta_winged_helix	61..141	CDD:153423	31/87 (36%)
		TFA2_Winged_2	141..200	CDD:465658	18/60 (30%)
gtf-2E2	NP_496466.1	TFIIE_beta_winged_helix	70..147	CDD:153423	31/79 (39%)
		TFA2_Winged_2	147..208	CDD:465658	18/60 (30%)