DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1316 and elavl3

DIOPT Version :9

Sequence 1:	NP_647887.1	Gene:	CG1316 / 38526	FlyBaseID:	FBgn0035526	Length:	470	Species:	Drosophila melanogaster
Sequence 2:	XP_012808614.1	Gene:	elavl3 / 594912	XenbaseID:	XB-GENE-490864	Length:	363	Species:	Xenopus tropicalis

Alignment Length:	380	Identity:	88/380 - (23%)
Similarity:	166/380 - (43%)	Gaps:	77/380 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSDYRSQSRSGGGR----GGQEYSNDDDPPMSRLFIICN---KAHTEEDFREAFSPYGEIEDIWV 58
            :|...:|:.:|.|.    .|...:.||    |:..:|.|   :..|:|:|:..|...||||...:
Frog     6 ISTMETQASNGPGSVGILNGTNGAADD----SKTNLIVNYLPQNMTQEEFKSLFGSIGEIESCKL 66

  Fly    59 VKDKHTQENKGIAYVKFSKTSDAAKAQEEMNGKTIGKMDRTLKVLVAANRNQGSNKSENEQEKYV 123
            |:||.|.::.|..:|.:...:||.||...:||..:  ..:|:||..|    :.|:.|..:...||
Frog    67 VRDKITGQSLGYGFVNYVDPNDADKAINTLNGLKL--QTKTIKVSYA----RPSSASIRDANLYV 125

  Fly   124 RLFIVIPKTATEEDIREEFSQWGDVESVTIVKEKNNGN-PKGFGYVRFTKFYYAAVAFENCSAKY 187
            .   .:|||..::::.:.|||:|.:.:..|:.::..|: .:|.|::||.|...|..|.:..:.:
Frog   126 S---SLPKTMNQKEMEQLFSQYGRIITSRILVDQVTGSVSRGVGFIRFDKRIEAEEAIKGLNGQ- 186

  Fly   188 KAVFAEPKGSTRTQRDQY-GRPSED------NPLYSSSGRGNSNFNGGGSSSGGGGSNSYNNDWN 245
                 :|.|::.....:: ..||:.      ..||.::.|..:           |..:.....:.
Frog   187 -----KPLGASEPITVKFANNPSQKTGQALLTHLYQTTARRYT-----------GPLHHQTQRFR 235

  Fly   246 VSQNNDMA-------AFL------------RMQNVPVAQPS----CLEV-NVSNCVNQDQLWRLF 286
            :....:||       :||            .:..|.:..|:    |:.| |:|...::..||:||
Frog   236 LDSLINMAYGVKSPLSFLPRFSPITIDSVTNLAGVSLTGPTTAGWCIFVYNLSPEADESVLWQLF 300

  Fly   287 DIIPGLDYCQIMREHGPRTNE----ALVVYDNPEAAIYAKDKLHGLEYPMGERII 337
            .....:...:::|:.  .||:    ..|...|.:.|..|...|:|  |.:|:|::
Frog   301 GPFGAVTNVKVIRDF--TTNKCKGFGFVTMTNYDEAAMAIASLNG--YRLGDRVL 351

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1316	NP_647887.1	RRM1_RBM45	25..105	CDD:240812	26/82 (32%)
		RRM2_RBM45	122..195	CDD:240813	18/73 (25%)
		RRM3_RBM45	267..339	CDD:240814	20/80 (25%)
		RRM4_RBM45	383..449	CDD:240815
elavl3	XP_012808614.1	ELAV_HUD_SF	32..362	CDD:273741	82/354 (23%)
		RRM1_Hu	34..111	CDD:241094	25/78 (32%)
		RRM_SF	116..206	CDD:302621	23/98 (23%)
		RRM3_HuC	279..363	CDD:241099	20/77 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910