DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1316 and RBM23

DIOPT Version :9

Sequence 1:	NP_647887.1	Gene:	CG1316 / 38526	FlyBaseID:	FBgn0035526	Length:	470	Species:	Drosophila melanogaster
Sequence 2:	XP_024305408.1	Gene:	RBM23 / 55147	HGNCID:	20155	Length:	515	Species:	Homo sapiens

Alignment Length:	202	Identity:	47/202 - (23%)
Similarity:	95/202 - (47%)	Gaps:	29/202 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 YRSQSRSGGGRGGQEYS---NDDDP---PMSRL--------FIICNKAHTE---EDFREAFSPYG 51
            |||...:.|.|.|...|   .:..|   |:..|        .:.|.:....   .|..:.||..|
Human   170 YRSPPLATGYRYGHSKSPHFREKSPVREPVDNLSPEERDARTVFCMQLAARIRPRDLEDFFSAVG 234

  Fly    52 EIEDIWVVKDKHTQENKGIAYVKFSKTSDAAKAQEEMNGKTIGKMDRTLKVLVAAN---RNQGSN 113
            ::.|:.::.|::::.:||||||:|.:......|......:.:|     :.::|.|:   :|:.:.
Human   235 KVRDVRIISDRNSRRSKGIAYVEFCEIQSVPLAIGLTGQRLLG-----VPIIVQASQAEKNRLAA 294

  Fly   114 KSENEQEKY---VRLFI-VIPKTATEEDIREEFSQWGDVESVTIVKEKNNGNPKGFGYVRFTKFY 174
            .:.|.|:..   :||:: .:....||:.:|..|..:|.::::.::|:.:.|..||:|::.|:...
Human   295 MANNLQKGNGGPMRLYVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDSDTGRSKGYGFITFSDSE 359

  Fly   175 YAAVAFE 181
            .|..|.|
Human   360 CARRALE 366

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1316	NP_647887.1	RRM1_RBM45	25..105	CDD:240812	19/93 (20%)
		RRM2_RBM45	122..195	CDD:240813	16/64 (25%)
		RRM3_RBM45	267..339	CDD:240814
		RRM4_RBM45	383..449	CDD:240815
RBM23	XP_024305408.1	RRM	143..514	CDD:330708	47/202 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910