DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1316 and tardbp

DIOPT Version :9

Sequence 1:	NP_647887.1	Gene:	CG1316 / 38526	FlyBaseID:	FBgn0035526	Length:	470	Species:	Drosophila melanogaster
Sequence 2:	XP_012821726.1	Gene:	tardbp / 394651	XenbaseID:	XB-GENE-974453	Length:	418	Species:	Xenopus tropicalis

Alignment Length:	229	Identity:	67/229 - (29%)
Similarity:	96/229 - (41%)	Gaps:	63/229 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    39 TEEDFREAFSPYGEIEDIWVVKDKHTQENKGIAYVKFSKTSDAAKAQEEMNGKTIGKMDRTLKVL 103
            ||:|.::.||.:||:..:.|.||..|..:||..:|:|:                    |...:|.
Frog   126 TEQDLKDYFSTFGEVIMVQVKKDAKTGHSKGFGFVRFA--------------------DYETQVK 170

  Fly   104 VAANRNQ----------GSNKSENEQEKYVRLFIVIPKTATE----EDIREEFSQWGDVESVTIV 154
            |.:.|:.          .::||.:|..:..::|:   ...||    |::|:.|||:|:|..|.|
Frog   171 VMSQRHMIDGRWCDCKLPNSKSPDEPMRSRKVFV---GRCTEDMSAEELRQFFSQYGEVVDVFI- 231

  Fly   155 KEKNNGNPKGFGYVRFTKFYYAAVAFENCSAK--YKAV-----FAEPKGSTRTQRDQYGR---PS 209
                   ||.|....|..|....||...|...  .|.|     .||||.:...|.::.||   ||
Frog   232 -------PKPFRAFAFVTFADDQVAQSLCGEDLIIKGVSVHVSTAEPKHNNNRQLERGGRFPGPS 289

  Fly   210 EDNPLY-----SSSGRGNSNFNGGGSSSGGGGSN 238
            ..|..|     ||...||   |.||:..||||.|
Frog   290 FGNQGYPNSRPSSGALGN---NQGGNMGGGGGMN 320

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1316	NP_647887.1	RRM1_RBM45	25..105	CDD:240812	17/65 (26%)
		RRM2_RBM45	122..195	CDD:240813	24/83 (29%)
		RRM3_RBM45	267..339	CDD:240814
		RRM4_RBM45	383..449	CDD:240815
tardbp	XP_012821726.1	RRM	<87..232	CDD:223796	34/136 (25%)
		RRM1_TDP43	115..191	CDD:240767	19/84 (23%)
		RRM	<190..>299	CDD:223796	36/119 (30%)
		RRM2_TDP43	200..270	CDD:240768	22/80 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910