DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1316 and elavl1b

DIOPT Version :9

Sequence 1:	NP_647887.1	Gene:	CG1316 / 38526	FlyBaseID:	FBgn0035526	Length:	470	Species:	Drosophila melanogaster
Sequence 2:	NP_570984.2	Gene:	elavl1b / 30065	ZFINID:	ZDB-GENE-000210-17	Length:	360	Species:	Danio rerio

Alignment Length:	354	Identity:	81/354 - (22%)
Similarity:	148/354 - (41%)	Gaps:	78/354 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 GQEYSNDDDPPMSRLFIICN---KAHTEEDFREAFSPYGEIEDIWVVKDKHTQENKGIAYVKFSK 77
            |.|....|:|..::..:|.|   :..::|:.|..||..||:|...:::||....:.|..:|.:..
Zfish    42 GYEDPMGDEPSDAKTNLIINYLPQNMSQEELRSLFSSIGEVESAKLIRDKMAGHSLGYGFVNYVN 106

  Fly    78 TSDAAKAQEEMNGKTIGKMDRTLKVLVAANRNQGSNKSENEQEKYVRLFIV-IPKTATEEDIREE 141
            .|||.:|...:||..:  ..:|:||..|...:.|.        |...|:|. :|||.|::::.:.
Zfish   107 PSDAERAINTLNGLRL--QSKTIKVSYARPSSDGI--------KDANLYISGLPKTMTQKNVEDM 161

  Fly   142 FSQWGDVESVTIVKEKNNGNPKGFGYVRFTKFYYAAVAFENCSAKYKAVFAEP------------ 194
            |:|:|.:.:..|:.::.:|..:|..::||.|...|..|.::.:....:..:||
Zfish   162 FTQYGRIINSRILVDQASGLSRGVAFIRFDKRSEAEEAIKDLNGSKPSGASEPITVKFAANPNQS 226

  Fly   195 KGST------RTQRDQYGRPSEDNP---LYS--SSGRGNSNFNGGGSSSGGGGSNSYNNDWNVSQ 248
            |.|.      .||..::|.|....|   .:|  |.....|:.|...|||.|         |
Zfish   227 KNSQLLSQLYHTQSRRFGGPVHHQPQRFRFSPMSVDHSVSSMNVASSSSSG---------W---- 278

  Fly   249 NNDMAAFLRMQNVPVAQPSCLEV-NVSNCVNQDQLWRLFDIIPGLDYCQIMREHGPRTNE----A 308
                               |:.| |:....::..||::|.....:...:::|:.  .|::    .
Zfish   279 -------------------CIFVYNLGQDADEGILWQMFGPFGAVTNVKVIRDF--NTSKCKGFG 322

  Fly   309 LVVYDNPEAAIYAKDKLHGLEYPMGERII 337
            .|...|.|.|..|...|:|  |.:|::::
Zfish   323 FVTMTNYEEAAMAISSLNG--YRLGDKVL 349

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1316	NP_647887.1	RRM1_RBM45	25..105	CDD:240812	23/82 (28%)
		RRM2_RBM45	122..195	CDD:240813	19/85 (22%)
		RRM3_RBM45	267..339	CDD:240814	17/76 (22%)
		RRM4_RBM45	383..449	CDD:240815
elavl1b	NP_570984.2	ELAV_HUD_SF	53..360	CDD:273741	77/343 (22%)
		RRM1_Hu	55..132	CDD:241094	22/78 (28%)
		RRM_SF	142..225	CDD:302621	19/82 (23%)
		RRM_SF	277..360	CDD:302621	19/109 (17%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910