DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1316 and Elavl3

DIOPT Version :9

Sequence 1:	NP_647887.1	Gene:	CG1316 / 38526	FlyBaseID:	FBgn0035526	Length:	470	Species:	Drosophila melanogaster
Sequence 2:	NP_034617.1	Gene:	Elavl3 / 15571	MGIID:	109157	Length:	367	Species:	Mus musculus

Alignment Length:	394	Identity:	94/394 - (23%)
Similarity:	157/394 - (39%)	Gaps:	111/394 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 QSRSGGGRGGQEYSN---------DDDPPMSRLFIICN---KAHTEEDFREAFSPYGEIEDIWVV 59
            :|:.|||..|....|         .||   |:..:|.|   :..|:::|:..|...|:||...:|
Mouse    10 ESQVGGGPAGPALPNGPLLGTNGATDD---SKTNLIVNYLPQNMTQDEFKSLFGSIGDIESCKLV 71

  Fly    60 KDKHTQENKGIAYVKFSKTSDAAKAQEEMNGKTIGKMDRTLKVLVAANRNQGSNKSENEQEKYVR 124
            :||.|.::.|..:|.:|..:||.||...:||..:  ..:|:||..|    :.|:.|..:...||.
Mouse    72 RDKITGQSLGYGFVNYSDPNDADKAINTLNGLKL--QTKTIKVSYA----RPSSASIRDANLYVS 130

  Fly   125 LFIVIPKTATEEDIREEFSQWGDVESVTIVKEKNNGNPKGFGYVRFTKFYYAAVAFENCSAKYKA 189
               .:|||.:::::.:.|||:|.:.:..|:.::..|..:|.|::||.|...|..|.:..:.:...
Mouse   131 ---GLPKTMSQKEMEQLFSQYGRIITSRILLDQATGVSRGVGFIRFDKRIEAEEAIKGLNGQKPL 192

  Fly   190 VFAEP----------------------KGSTRTQRDQYGRPSE--------DNPLYSSSG----- 219
            ..|||                      :.|.|    :|..|..        ||.|..:.|
Mouse   193 GAAEPITVKFANNPSQKTGQALLTHLYQSSAR----RYAGPLHHQTQRFRLDNLLNMAYGVKSPL 253

  Fly   220 -----------RGNSNFNGGGSSSGGGGSNSYNNDWNVSQNNDMAAFLRMQNVPVAQPSCLEV-N 272
                       .|.|...|.|.|.|..|:.     |                       |:.| |
Mouse   254 SLIARFSPIAIDGMSGLAGVGLSGGAAGAG-----W-----------------------CIFVYN 290

  Fly   273 VSNCVNQDQLWRLFDIIPGLDYCQIMREHGPRTNE----ALVVYDNPEAAIYAKDKLHGLEYPMG 333
            :|...::..||:||.....:...:::|:.  .||:    ..|...|.:.|..|...|:|  |.:|
Mouse   291 LSPEADESVLWQLFGPFGAVTNVKVIRDF--TTNKCKGFGFVTMTNYDEAAMAIASLNG--YRLG 351

  Fly   334 ERII 337
            ||::
Mouse   352 ERVL 355

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1316	NP_647887.1	RRM1_RBM45	25..105	CDD:240812	25/82 (30%)
		RRM2_RBM45	122..195	CDD:240813	21/94 (22%)
		RRM3_RBM45	267..339	CDD:240814	21/76 (28%)
		RRM4_RBM45	383..449	CDD:240815
Elavl3	NP_034617.1	ELAV_HUD_SF	36..366	CDD:273741	87/368 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910