DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1316 and MSI2

DIOPT Version :9

Sequence 1:	NP_647887.1	Gene:	CG1316 / 38526	FlyBaseID:	FBgn0035526	Length:	470	Species:	Drosophila melanogaster
Sequence 2:	XP_005257071.1	Gene:	MSI2 / 124540	HGNCID:	18585	Length:	346	Species:	Homo sapiens

Alignment Length:	178	Identity:	44/178 - (24%)
Similarity:	73/178 - (41%)	Gaps:	39/178 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 SGGGRGGQEYSNDDDPPMSRLFIICNKAHTEED-FREAFSPYGEIEDIWVVKDKHTQENKGIAYV 73
            :.|.:|....:||......::||......|..| .|:.||.:|||.:..|::|..|:.::|..:|
Human     3 ANGSQGTSGSANDSQHDPGKMFIGGLSWQTSPDSLRDYFSKFGEIRECMVMRDPTTKRSRGFGFV 67

  Fly    74 KFSKTSDAAKA----QEEMNGKTIG-----------KM-DRTLKVLVAANRNQGSNKSENEQEKY 122
            .|:..:...|.    ..|::.|||.           || .||.|:.|..
Human    68 TFADPASVDKVLGQPHHELDSKTIDPKVAFPRRAQPKMVTRTKKIFVGG---------------- 116

  Fly   123 VRLFIVIPKTATEEDIREEFSQWGDVESVTIVKEKNNGNPKGFGYVRF 170
                  :......||:::.|.|:|.||...::.:|.....:|||:|.|
Human   117 ------LSANTVVEDVKQYFEQFGKVEDAMLMFDKTTNRHRGFGFVTF 158

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1316	NP_647887.1	RRM1_RBM45	25..105	CDD:240812	26/96 (27%)
		RRM2_RBM45	122..195	CDD:240813	13/49 (27%)
		RRM3_RBM45	267..339	CDD:240814
		RRM4_RBM45	383..449	CDD:240815
MSI2	XP_005257071.1	RRM1_MSI2	17..109	CDD:410153	23/91 (25%)
		PABP-1234	<35..343	CDD:130689	37/146 (25%)
		RRM2_MSI	111..184	CDD:240769	15/70 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910