Protein Alignment CG1316 and CELF3

DIOPT Version :9

• Sequence 1: NP_647887.1
• Gene: CG1316 / 38526
• FlyBaseID: FBgn0035526
• Length: 470
• Species: Drosophila melanogaster
• Sequence 2: NP_009116.3
• Gene: CELF3 / 11189
• HGNCID: 11967
• Length: 465
• Species: Homo sapiens
• Alignment Length: 502
• Identity: 107/502 - (21%)
• Similarity: 191/502 - (38%)
• Gaps: 128/502 - (25%)

  Fly    24 DPPMSRLFIICNKAHTEE-DFREAFSPYGEIEDIWVVKDKHTQENKGIAYVKFSKTSDAAKAQEE 87
            :|...:||:.....|.|| |.:..|..:|.|.::.|:|||:|..:||.|::.:.....|.|||..
Human     3 EPDAIKLFVGQIPRHLEEKDLKPIFEQFGRIFELTVIKDKYTGLHKGCAFLTYCARDSALKAQSA 67

  Fly    88 MN-GKTIGKMDRTLKVLVAANRNQGSNKSENEQEKYVRLFI-VIPKTATEEDIREEFSQWGDVES 150
            :: .||:..|:|.::|..|.:.::|.::         :||: ::.|..|:||:|:.|..:|.::.
Human    68 LHEQKTLPGMNRPIQVKPADSESRGEDR---------KLFVGMLGKQQTDEDVRKMFEPFGTIDE 123

  Fly   151 VTIVKEKNNGNPKGFGYVRFTKFYYAAVAFE---------NCSAKYKAVFAE---PKGSTRTQR- 202
            .|:::.. :|..||..:|:|.....|..|..         ..|:.....||:   .:|..|.|:
Human   124 CTVLRGP-DGTSKGCAFVKFQTHAEAQAAINTLHSSRTLPGASSSLVVKFADTEKERGLRRMQQV 187

  Fly   203 -DQYGRPSEDNPLYSSSGRGNSNFNGGGSSSGGGGSNSYNNDWNVSQNNDMAAFLRMQNV---PV 263
             .|.|..|   |:....|..::                    :..:.....||.:...:.   |:
Human   188 ATQLGMFS---PIALQFGAYSA--------------------YTQALMQQQAALVAAHSAYLSPM 229

  Fly   264 AQPSCLEVNVSNCVNQDQLWRLFDIIPGLDYCQIMREHGPRTNEALVVYDNPEAAIYAKDKLHGL 328
            |..:.:::.....:|.:          ||....|....|..|..|:..  .|.:||.|...::|.
Human   230 ATMAAVQMQHMAAINAN----------GLIATPITPSSGTSTPPAIAA--TPVSAIPAALGVNGY 282

  Fly   329 E----YPMGERI--IVKVNGMS--SARMDTSFIDKRTKKDA------------------------ 361
            .    .|.|:..  .:..||:.  .|:...:.:|...:..|
Human   283 SPVPTQPTGQPAPDALYPNGVHPYPAQSPAAPVDPLQQAYAGMQHYTAAYPAAYSLVAPAFPQPP 347

  Fly   362 --ICNVPLPPTQPLASPDDQVAQR----------LFI-----------VLSANLP--HSILKNIF 401
              :...|.||.|.......|..|:          :||           :|...:|  |.|...:|
Human   348 ALVAQQPPPPPQQQQQQQQQQQQQQQREGPDGCNIFIYHLPQEFTDSEILQMFVPFGHVISAKVF 412

  Fly   402 SCWSGLIDVYLLPNKNCGYVKYAEVESAQLAIRTLNGAEICGTKIKV 448
                  :|.....:|..|:|.:....|||.||:.:||.:|...::||
Human   413 ------VDRATNQSKCFGFVSFDNPASAQAAIQAMNGFQIGMKRLKV 453

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG1316	NP_647887.1	RRM1_RBM45	25..105	CDD:240812	27/81 (33%)
		RRM2_RBM45	122..195	CDD:240813	20/85 (24%)
		RRM3_RBM45	267..339	CDD:240814	14/77 (18%)
		RRM4_RBM45	383..449	CDD:240815	21/89 (24%)
CELF3	NP_009116.3	RRM1_CELF3_4_5_6	2..88	CDD:410041	28/84 (33%)
		RRM2_CELF3_4_5_6	94..174	CDD:410043	19/89 (21%)
		PRK12323	<214..>351	CDD:237057	23/148 (16%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	346..379		6/32 (19%)
		RRM3_CELF3_4_5_6	376..454	CDD:241083	21/84 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910