Protein Alignment CG1316 and CELF2

DIOPT Version :9

• Sequence 1: NP_647887.1
• Gene: CG1316 / 38526
• FlyBaseID: FBgn0035526
• Length: 470
• Species: Drosophila melanogaster
• Sequence 2: XP_024303540.1
• Gene: CELF2 / 10659
• HGNCID: 2550
• Length: 549
• Species: Homo sapiens
• Alignment Length: 540
• Identity: 116/540 - (21%)
• Similarity: 202/540 - (37%)
• Gaps: 148/540 - (27%)

  Fly    15 GGQEYSNDDDPPMSRLFI-ICNKAHTEEDFREAFSPYGEIEDIWVVKDK--HTQENKGIAYVKFS 76
            |..::|:..||...::|: ...::.:|::.:|.|.|||.:..|.|::|:  :..::||..:|.|.
Human    58 GALDHSDQPDPDAIKMFVGQIPRSWSEKELKELFEPYGAVYQINVLRDRSQNPPQSKGCCFVTFY 122

  Fly    77 KTSDAAKAQEEM-NGKTIGKMDRTLKVLVAANRNQGSNKSENEQEKYVRLFI-VIPKTATEEDIR 139
            ....|.:||..: |.||:..|...:::..|     .|.||...:::  :||| ::.|...|.|||
Human   123 TRKAALEAQNALHNIKTLPGMHHPIQMKPA-----DSEKSNAVEDR--KLFIGMVSKKCNENDIR 180

  Fly   140 EEFSQWGDVESVTIVKEKNNGNPKGFGYVRFT---------KFYYAAVAFENCSAKYKAVFAEPK 195
            ..||.:|.:|...|::.. :|..:|..:|.|:         |..:.:...|.||:.....||:
Human   181 VMFSPFGQIEECRILRGP-DGLSRGCAFVTFSTRAMAQNAIKAMHQSQTMEGCSSPIVVKFAD-- 242

  Fly   196 GSTRTQRDQYGRPSEDNPLYSSSGRGNSNFNGG--GSSSGGGG-----------SNSYNNDWNVS 247
                ||:|:     |...|.....:.....|..  |:.:|.||           :.|.:|....|
Human   243 ----TQKDK-----EQRRLQQQLAQQMQQLNTATWGNLTGLGGLTPQYLALLQQATSSSNLGAFS 298

  Fly   248 QNNDMAAF--LRMQNV-------PVAQPSCLEVNVSNCVNQDQLWRLFDIIPGLDYCQIMREHGP 303
            ....||..  |::||:       ..||.|....|.:..                          .
Human   299 GIQQMAGMNALQLQNLATLAAAAAAAQTSATSTNANPL--------------------------S 337

  Fly   304 RTNEALVVYDNPEAA-------------IYAKDKLHGLEYPMGERI-IVKVNGMSS----ARM-- 348
            .|:.||....:|.||             :.:...|.||   .|..: :..:|.::.    |:|
Human   338 TTSSALGALTSPVAASTPNSTAGAAMNSLTSLGTLQGL---AGATVGLNNINALAGTINIAQMLS 399

  Fly   349 -----------------DTSFIDKRT------KKDAICNVPLPPTQPLASPDDQVAQR------- 383
                             ....:|..|      ::.|...:|...:|.|.........:
Human   400 GMAALNGGLGATGLTNGTAGTMDALTQAYSGIQQYAAAALPTLYSQSLLQQQSAAGSQKEGPEGA 464

  Fly   384 -LFIVLSANLPHSI----LKNIFSCWSGLIDVYLLPNK-----NC-GYVKYAEVESAQLAIRTLN 437
             |||.   :||...    :..:|..:..:|...:..:|     .| |:|.|....|||.||:.:|
Human   465 NLFIY---HLPQEFGDQDILQMFMPFGNVISAKVFIDKQTNLSKCFGFVSYDNPVSAQAAIQAMN 526

  Fly   438 GAEICGTKIKVMEAEERSGS 457
            |.:|...::||.....::.|
Human   527 GFQIGMKRLKVQLKRSKNDS 546

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG1316	NP_647887.1	RRM1_RBM45	25..105	CDD:240812	22/83 (27%)
		RRM2_RBM45	122..195	CDD:240813	23/82 (28%)
		RRM3_RBM45	267..339	CDD:240814	12/85 (14%)
		RRM4_RBM45	383..449	CDD:240815	21/83 (25%)
CELF2	XP_024303540.1	RRM1_CELF1_2_Bruno	70..153	CDD:241075	22/87 (25%)
		RRM2_CELF1_2	162..242	CDD:241078	22/82 (27%)
		RRM3_CELF1_2	457..548	CDD:241082	23/93 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910