Protein Alignment Ctl1 and Slc44a1

DIOPT Version :10

• Sequence 1: NP_647884.1
• Gene: Ctl1 / 38523
• FlyBaseID: FBgn0035523
• Length: 691
• Species: Drosophila melanogaster
• Sequence 2: XP_038966811.1
• Gene: Slc44a1 / 85254
• RGDID: 621426
• Length: 723
• Species: Rattus norvegicus
• Alignment Length: 636
• Identity: 223/636 - (35%)
• Similarity: 353/636 - (55%)
• Gaps: 64/636 - (10%)

  Fly    21 RSCTDTCWLAIYIIFWLFLIVIAIFSFVYGNPLRIINGYDSFGNTCGVKYNEKFQGFPLSGMNTL 85
            |||||..||.::::|.:.:..|..||...|...|:::||||:||.||.: |.|.:....||::..
  Rat    28 RSCTDIPWLLLFVLFCIGMGFICGFSVATGAAARLVSGYDSYGNICGQR-NAKLEAIANSGLDHT 91

  Fly    86 DKPELFYFD------VKELKKSLKICVKSCPAKTMTKGSELLEYYSQTGTQLCKYDYNMQQLTTA 144
            .:..:|:.|      :....||:.:||.:||.:.:...|::.::....|:.||.|:....:.|..
  Rat    92 HRKYVFFLDPCNLDLINRKIKSMALCVAACPRQELKTLSDVQKFAEINGSALCSYNIKPSEYTLT 156

  Fly   145 GNDAKTFNFLGPCPSFPVHESSPV--LHRCVPKGT---GEKVQNYYDMLNNWDVAQQFVGDIYST 204
               ||:..|   ||..||..|:|:  .|||.|...   .:..:.....:::..|..:.:..:.::
  Rat   157 ---AKSSAF---CPKLPVPASAPIPFFHRCAPVNISCYAKFAEALITFVSDNSVLHRLISGVMTS 215

  Fly   205 WHIIAMVCGLALLISIALVTMMHWLSRIVSWIICVLVIVASVALTVALWYAYYNIR---NKSGVN 266
            ..||..:|.|:|::|:.|:.::.::||::.||:.:|||:.|:..|..||:.|...|   .::.:.
  Rat   216 KEIILGLCLLSLVLSMILMVIIRYISRVLVWILTILVILGSLGGTGVLWWLYAKQRRSPKETVIP 280

  Fly   267 TQYSMLEEFVRNQQAVLTLAVLATITMIILIVVIYFLKNKLAGLSALFEEAGQCMMNLPGLLIAP 331
            .|..:.|:   |.:|:|..|:.||:..:||.:::..::.::|...|||..||:..::||.|:..|
  Rat   281 EQLQIAED---NLRALLIYAISATVFTVILFLIMLVMRKRVALTIALFHVAGKVFIHLPLLVFQP 342

  Fly   332 LLAFLVLIAFLSFWVAVIICLATASSPGQSPIAPFDNSKAHQQPLPANALFVSNSTDVNDLRPNA 396
            ...|..|:.|.::|:..::.|.|..|..|:                                ...
  Rat   343 FWTFFALVLFWAYWIMTLLFLGTTGSAVQN--------------------------------EQG 375

  Fly   397 RVEYADAGVLRSMFWIYVVGLIWTVEFIFACQQFALAAAVAFWYFQKPTS----TPTFYAIGKLV 457
            .|||..:|.|:.|:|.:||||||..|||.||||..:|.||..:||.:...    ||...::.:|:
  Rat   376 FVEYKISGPLQYMWWYHVVGLIWISEFILACQQMTVAGAVVTYYFTRDKRNLPFTPILASVNRLI 440

  Fly   458 KYHLGTVAKGSFVITIFKIPRLILTYLYAKLKKGEDKGSECAACCLKCCICGFWLLEKFIRFLNH 522
            :|||||||||||:||:.||||:||.|::::||   .|.:.||.|.||.|||..|.|||.:.:||.
  Rat   441 RYHLGTVAKGSFIITLVKIPRMILMYIHSQLK---GKENACARCMLKSCICCLWCLEKCLSYLNQ 502

  Fly   523 NAYTVVAIESINFCPAAGIAWNAMATNVLQVATINSVGDFILFLGKVVVAALSGLIGIVLLKDKP 587
            ||||..||.|.|||.:|..|:..:..|.|:||.||:||||:||||||::...:||.||:||..:.
  Rat   503 NAYTATAINSTNFCTSAKDAFVILVENALRVAAINTVGDFMLFLGKVLIVCSTGLAGIMLLNYQQ 567

  Fly   588 GLNFYMAPVIIIIIFSFFIAHIILSLFEMVVDTLFLCVCEDKTLN-GRSGR 637
            ....::.|:||:.:|:|.:||..||::|||||.||||...|...| |..||
  Rat   568 DYTVWVLPLIIVCLFAFLVAHCFLSIYEMVVDVLFLCFAIDTKYNDGSPGR 618

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ctl1	NP_647884.1	Choline_transpo	287..629	CDD:461337	139/345 (40%)
Slc44a1	XP_038966811.1	Choline_transpo	298..608	CDD:461337	139/344 (40%)