DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ctl1 and AT3G15380

DIOPT Version :9

Sequence 1:	NP_647884.1	Gene:	Ctl1 / 38523	FlyBaseID:	FBgn0035523	Length:	691	Species:	Drosophila melanogaster
Sequence 2:	NP_566511.1	Gene:	AT3G15380 / 820777	AraportID:	AT3G15380	Length:	700	Species:	Arabidopsis thaliana

Alignment Length:	766	Identity:	178/766 - (23%)
Similarity:	310/766 - (40%)	Gaps:	183/766 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MGCAESKDG----EGEAQNNRPKYRSCTDTCWLAIYIIFWLFLIVIAIFSFVYGNPLRIINGYDS 61
            :|...|.||    :|..::|    |.|.|..:|.|:|.||:.:||.:.|.|..|||||:..|.|.
plant     9 IGRYTSSDGSAPNDGIIKHN----RKCRDITFLIIFIAFWVSMIVNSSFGFNQGNPLRLTYGLDY 69

  Fly    62 FGNTCGVKYNEKFQGFPLSGMNTLDKPELFYF--------------DVKELKKSLKICVKSCPAK 112
            .||.||.|:..:          .|.:.||.|:              ::| |..:..||:..|||.
plant    70 EGNVCGSKHRHR----------DLTQLELRYWLNPNQVYESGLKDGELK-LANARTICLLDCPAP 123

  Fly   113 TMTKGSELLEYYSQTGTQLCKY---------------DYNMQQLTTAGNDAKTFNFLGPC----- 157
            :           ..|...:|.|               :|:..:..|......:....|||
plant   124 S-----------DDTLNWVCDYPDGEIRLKMNDWIDRNYDYFEFLTPEMRNSSLQLQGPCYPVIF 177

  Fly   158 PSFPVHESSPVLHRCVPKGT-------GEKVQNYYDML----------NNWDVAQQFVGDIYSTW 205
            ||..|:.|...:.|......       |..:|.  ||:          :...|.:::|.||..:|
plant   178 PSVNVYWSCQYIARASNSSLRHWQQMGGVNIQE--DMIIDKSIRRSMNSRASVLKRYVADIGKSW 240

  Fly   206 HIIAMVCG--LALLISIALVTMMHWLSRIVSWIICVLVIVASVALTV-----ALWYAYYNIRNKS 263
            .:: :|||  :.|.:||..:.::......:.||..||..:..:::||     |.|.....:....
plant   241 PVL-IVCGGLVPLFLSIIWLLLIRHFVAAMPWITVVLFNMLLISVTVFYYLKAGWIGNDAVTPII 304

  Fly   264 GVNTQYSMLEEFVRNQQAVLTLAVLATITMIILIVVIYFLKNKLAGLSALFEEAGQCMMNLPGLL 328
            |.:..|  ...:.|....|..:|:|.|...::.|:....:..::...:::.:.|.:.:..:..|:
plant   305 GEHDPY--FHVYGRELTHVRGVAILMTFISVVAILTSIAIIRRILMATSVLKVAAKVIGEVQALI 367

  Fly   329 IAPLLAFLVLIAFLSFWVAVIICLATASSPGQSPIAPFDNSKAHQQPLPANALFVSNSTDVN--- 390
            |.|.:.|.:|..|..||::..:.|   .|.||                    :..:|..:.|
plant   368 IFPAIPFAMLAIFYMFWISAALHL---FSSGQ--------------------VVQNNCNNTNCCA 409

  Fly   391 -DL---RPNA------RVEYADAGVLRSMFWIYVVGLIWTVEFIFACQQFALAAAVAFWYFQKPT 445
             ||   :.|.      .:.|.....:...|.::  |..|..:|..|.....:|.:||.:|:.:..
plant   410 YDLVLKKVNCDRCCGYSIHYTPHITIAIFFHLF--GCYWATQFFIASSATVIAGSVASYYWAQGE 472

  Fly   446 ST------PTFYAIGKLVKYHLGTVAKGSFVITIFKIPRLILTYLYAKLKKG------------- 491
            ::      |.|.::.:|.:|:||:||.||.:::..:..|.||..:..|.|..
plant   473 ASPEIPFLPVFASMKRLARYNLGSVALGSLIVSFVESVRFILEAIRRKTKVSGTIPDHWFWRMAH 537

  Fly   492 -EDKGSECAACCLKCCICGFWLLEKFIRFLNHNAYTVVAIESINFCPAAGIAWNAMATNVLQVAT 555
             ..:|      |||.       :|..|:.:|.|||.::||...:||.::.||...:.:|:|::..
plant   538 YTSRG------CLKS-------VEWTIKSVNRNAYIMIAITGKSFCKSSAIATELIISNILRIGK 589

  Fly   556 INSVGDFILFLGKVVVAALSGLIGIVLLKDKPGLNFYMA----------PVIIIIIFSFFIAHII 610
            :|.:||.||||||:.|:..|.|.|.::|..    :.|.|          ||:......:.:|.:.
plant   590 VNVIGDVILFLGKLCVSLFSALFGFLMLDS----HRYRASHNKVSSPLLPVLACWALGYIVATLF 650

  Fly   611 LSLFEMVVDTLFLCVCEDKTLNGRSGRWAQSNLAKLVGEEPLQPGEEPPIE 661
            .::.||.:||:.|..|:|...|..:.:.|...|.     |.|...:|..::
plant   651 FAVVEMSIDTIILSFCQDSEENQGNAQHAPPLLL-----ETLDSNQEEEVQ 696

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ctl1	NP_647884.1	DUF4481	<207..>316	CDD:291466	22/115 (19%)
Ctl1	NP_647884.1	Choline_transpo	286..629	CDD:282384	90/385 (23%)
AT3G15380	NP_566511.1	Choline_transpo	326..668	CDD:309592	89/383 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	67	1.000	Domainoid score	I3541
eggNOG	1	0.900	-	-		E1_KOG1362
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	170	1.000	Inparanoid score	I1549
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D329225at2759
OrthoFinder	1	1.000	-	-		FOG0000381
OrthoInspector	1	1.000	-	-		otm3077
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR12385
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	11	10.930