Protein Alignment Ctl1 and Slc44a4

DIOPT Version :9

• Sequence 1: NP_647884.1
• Gene: Ctl1 / 38523
• FlyBaseID: FBgn0035523
• Length: 691
• Species: Drosophila melanogaster
• Sequence 2: XP_006524948.1
• Gene: Slc44a4 / 70129
• MGIID: 1917379
• Length: 716
• Species: Mus musculus
• Alignment Length: 711
• Identity: 203/711 - (28%)
• Similarity: 328/711 - (46%)
• Gaps: 112/711 - (15%)

  Fly    19 KYRSCTDTCWLAIYIIFWLFLIVIAIFSFVYGNPLRIINGYDSFGNTCGVKYNEKFQGFPLSGMN 83
            |.|.|||.....:::||.|..|::.:.::|||:|.:::...:|.|..|||..|:
Mouse    35 KNRGCTDIICCVLFLIFILGYIIVGLVAWVYGDPRQVLYPRNSTGAYCGVGDNK----------- 88

  Fly    84 TLDKPELFYFDVKELKKSL---------------KICVKSCPAKTMTKGSELLEYYSQTG----- 128
              |||.:.|||:.....::               ::||.|||....  ..|:.::....|
Mouse    89 --DKPYVLYFDILSCAAAINIISIAENGLQCPTPQVCVSSCPLAPW--AVEVFQFSKTVGEVYGE 149

  Fly   129 -TQLCKYDYNMQQLTTAGNDAKTFNFL--GPCPSFPVHESSPVLHRCVP---------------- 174
             ...|        |.....|......|  |.||.| :..|:|.|.||.|
Mouse   150 RRNFC--------LPAVSPDMIVEESLQKGLCPRF-LLPSTPALGRCFPLPNINFTLPEDLRINN 205

  Fly   175 KGTGEKVQNYYDMLNNWDVAQQFVGDIYSTWHIIAMVCGLALLISIALVTMMHWLSRIVSWIICV 239
            ......:....|.:|..||:.:...|...:|:.|.:..|:||.:|:..:.::    |:|:..:.:
Mouse   206 TTVSNGISGLLDSINARDVSVKIFEDFAQSWYWILVALGVALALSLLFILLL----RLVAAPLVL 266

  Fly   240 LVIVASVALTV----ALWYAYYNIRNKSGVNTQYSMLEEFVRNQQ-------AVLTLAVLATITM 293
            |:||..:|:..    ..|..|...|:|....||......|...|.       |::.||||..|.:
Mouse   267 LLIVGVLAVLAYGIYHCWQQYQVFRDKGASITQLGFTTNFSAYQSVKETWLAALIVLAVLEGILL 331

  Fly   294 IILIVVIYFLKNKLAGLSALFEEAGQCMMNLPGLLIAPLLAFLVLIAFLSFWVAVIICLATASSP 358
            ::||    ||:.::....||.:||.:.:..:...:..||:.|::|:..:.:|....:.|||:..|
Mouse   332 LMLI----FLRQRIRIAIALLKEASRAVGQMMSTMFYPLVTFVLLVICIGYWAVTALYLATSGQP 392

  Fly   359 GQSPIAPFDNSKAHQQPLPANALFVSNSTDVNDLRPNARV---EYADAGVL-RSMF--WIY-VVG 416
             |......:.|....:.:|.| :.......:|...||.:.   .|:..|:. ||:|  .|| |:|
Mouse   393 -QYIYWASNTSTPGCENVPVN-MTCDPMAPLNSSCPNLKCVFKGYSTTGLAQRSLFNLQIYGVLG 455

  Fly   417 LIWTVEFIFACQQFALAAAVA--FWYFQKPTSTPTF---YAIGKLVKYHLGTVAKGSFVITIFKI 476
            |.|||.::.|..|..||.|.|  :|.|.||...|||   .|..:.::||.|::|.|:.::::.:|
Mouse   456 LFWTVNWVLALGQCVLAGAFASFYWAFHKPRDIPTFPLSSAFIRTLRYHTGSLAFGALILSLVQI 520

  Fly   477 PRLILTYLYAKLKKGEDKGSECAACCLKCCICGFWLLEKFIRFLNHNAYTVVAIESINFCPAAGI 541
            .|:||.|:..||:..::..:.|..||.|||:   |.|||||:|||.|||.::||...|||.:|..
Mouse   521 ARVILEYIDHKLRGSQNPVARCIICCFKCCL---WCLEKFIKFLNRNAYIMIAIYGKNFCVSAKN 582

  Fly   542 AWNAMATNVLQVATINSVGDFILFLGKVVVAALSGLIGIVLLK----------DKPGLNFYMAPV 596
            |:..:..|||:|..::.|.|.:||.||::|....|::......          :.|.||:|..|:
Mouse   583 AFMLLMRNVLRVVVLDKVTDLLLFFGKLLVVGGVGVLSFFFFSGRIKGLGKDFENPNLNYYWLPI 647

  Fly   597 IIIIIFSFFIAHIILSLFEMVVDTLFLCVCEDKTLNGRSGR---WAQSNLAKLVGEEPLQP 654
            :..|:.::.||....|:|.|.|||||||..||...|..|..   :....|.|::|::...|
Mouse   648 MTSIMGAYVIASGFFSVFGMCVDTLFLCFLEDLERNDGSQERPYYMPKALLKILGKKNEAP 708

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ctl1	NP_647884.1	DUF4481	<207..>316	CDD:291466	31/119 (26%)
		Choline_transpo	286..629	CDD:282384	123/364 (34%)
Slc44a4	XP_006524948.1	Choline_transpo	321..681	CDD:367975	125/368 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1362
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D329225at2759
OrthoFinder	1	1.000	-	-		FOG0000381
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.820