Protein Alignment Ctl1 and slc44a5b

DIOPT Version :10

• Sequence 1: NP_647884.1
• Gene: Ctl1 / 38523
• FlyBaseID: FBgn0035523
• Length: 691
• Species: Drosophila melanogaster
• Sequence 2: XP_068079072.1
• Gene: slc44a5b / 558142
• ZFINID: ZDB-GENE-081105-4
• Length: 749
• Species: Danio rerio
• Alignment Length: 741
• Identity: 197/741 - (26%)
• Similarity: 337/741 - (45%)
• Gaps: 157/741 - (21%)

  Fly     9 GE-GEAQNNRPKY------RSCTDTCWLAIYIIFWLFLIVIAIFSFVYGNPLRIINGYDSFGNTC 66
            || ||.....|.:      |.|||.....|::|..|..||:...::::|:|.:::...||:|..|
Zfish    11 GELGEPHKFDPTFRGPVHKRGCTDVLCCVIFVIVILGYIVLGTVAWMHGDPRKVVYPTDSYGQFC 75

  Fly    67 GVKYNEKFQGFPLSGMNTLDKPELFYFDVKELKK----------SLKICVKSCPAKTMT------ 115
            |.      |..|     ..:|..||||::.:...          :.::||..||.:..|
Zfish    76 GQ------QETP-----NANKAILFYFNILQCANPSVLINLQCPTTQLCVSKCPDRFATYIDMQY 129

  Fly   116 -----KGSELLEYYSQTGTQLCKYDYNMQQLTTAGNDAKTFNFL---GPCPSFPVHESSPVLHRC 172
                 |||  .|||.    |.||..:|        |..|..:.:   ..|||..| .|.|.|.||
Zfish   130 SYRRNKGS--WEYYK----QFCKPGFN--------NPDKPISQVLRDEDCPSMIV-PSRPFLQRC 179

  Fly   173 VP------------------KGTGEKVQNYYD-----------------------------MLNN 190
            .|                  .|.| |:::..|                             :|:.
Zfish   180 FPDFITRNGTLTVANQTSFKDGHG-KIRSVVDLRDAAKQERTVLSGKVTAMQQGTESGITSLLDA 243

  Fly   191 WDVAQQFVGDIYSTWHIIAMVCGLALLISIALVTMMHWLSRIVSWIICVLVIVASVALTVALWYA 255
            .:|..:...|..|:|..|.:...:::|:|:..:.::.:.:.::.|:: :..::|:|.  ..:|:.
Zfish   244 KEVGTKIFEDYASSWFWILIGLVISMLVSLVFILLLRFTAGVLFWLV-IFGVIAAVG--YGIWHC 305

  Fly   256 YY---NIRNKS---------GVNTQYSMLEEFVRNQQAVLTLAVLATITMIILIVVIYFLKNKLA 308
            |:   :::.|.         |..|.:.:..:.  :|..::.:..||.|..||::|:| ||:|::.
Zfish   306 YWEYSSLKGKPDSDVTISDIGFQTDFRVYLQL--SQTWLIFMTSLAVIEAIIILVLI-FLRNRVR 367

  Fly   309 GLSALFEEAGQCMMNLPGLLIAPLLAFLVLIAFLSFWVAVIICLATASSPGQSPIAPFDNSKAHQ 373
            ...||.:|..:.:..:...|..|::.||:|...:::|....:.||::.......::...:.|...
Zfish   368 IAIALLKEGSKAIGCIMSTLFYPIITFLLLALCIAYWAVTAVFLASSGEAVYKVMSTLPDCKYTN 432

  Fly   374 QPLPANALFVSNSTDVNDLRPNARVEYADAGVLRSMF--WIYVVGL------IWTVEFIFACQQF 430
            ..........||   |..|.|.::..:|..|. .|::  :|:|:.|      :|.|.|..|..|.
Zfish   433 LTCDPETFSQSN---VTKLCPGSQCTFAFYGG-ESLYHRYIFVLQLCNLLVFLWLVNFTIALGQC 493

  Fly   431 ALAAAVA--FWYFQKPTS---TPTFYAIGKLVKYHLGTVAKGSFVITIFKIPRLILTYLYAKLKK 490
            .||.|.|  :|..:||..   .|...:.|:.::||.|::|.|:.:::|.:..|:||.||..|||.
Zfish   494 TLAGAFAAYYWALRKPADIPPCPLASSFGRALRYHTGSLAFGALILSIVQFIRIILEYLDHKLKG 558

  Fly   491 GEDKGSECAACCLKCCICGFWLLEKFIRFLNHNAYTVVAIESINFCPAAGIAWNAMATNVLQVAT 555
            ..:..:....||||||   ||.||.||:|:|.|||.:::|...|||.:|..|:..:..||::||.
Zfish   559 AHNAFTRFLLCCLKCC---FWCLEHFIKFMNRNAYIMISIYGKNFCTSARDAFFLLMRNVMRVAV 620

  Fly   556 INSVGDFILFLGKVVVAALSGLIGI-----------VLLKDKPGLNFYMAPVIIIIIFSFFIAHI 609
            ::.|.||:|||||:::   ||.:|:           |:.::.|.||:|..|::.:|..|:.|||.
Zfish   621 LDKVTDFLLFLGKLLI---SGSVGVLAFFFFTRQIPVIQEEVPSLNYYWVPLLTVIFGSYMIAHG 682

  Fly   610 ILSLFEMVVDTLFLCVCEDKTLNGRS 635
            ..:::.|.|||||||...|...|..|
Zfish   683 FFNVYAMCVDTLFLCFLLDLEKNDGS 708

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ctl1	NP_647884.1	Choline_transpo	287..629	CDD:461337	118/365 (32%)
slc44a5b	XP_068079072.1	Choline_transpo	348..703	CDD:461337	119/365 (33%)