Protein Alignment Ctl1 and slc44a1b

DIOPT Version :10

• Sequence 1: NP_647884.1
• Gene: Ctl1 / 38523
• FlyBaseID: FBgn0035523
• Length: 691
• Species: Drosophila melanogaster
• Sequence 2: XP_021336769.1
• Gene: slc44a1b / 503933
• ZFINID: ZDB-GENE-050309-63
• Length: 752
• Species: Danio rerio
• Alignment Length: 702
• Identity: 234/702 - (33%)
• Similarity: 362/702 - (51%)
• Gaps: 113/702 - (16%)

  Fly    21 RSCTDTCWLAIYIIFWLFLIVIAIFSFVYGNPLRIINGYDSFGNTCGVKYNEKFQGFPLSGMNTL 85
            |||||..|..::.:|.:.:..|..|:...|...|::.||||:|||||.: ||..:|..|||::..
Zfish    32 RSCTDLPWFLLFTLFLVGMCGICGFTIATGGAARLVFGYDSYGNTCGQR-NEPIEGVRLSGLDHT 95

  Fly    86 DKPELFYFD------VKELKKSLKICVKSCPAKTMTKGSELLEYYS------QTGTQLCKYDYNM 138
            |:..:|:.|      ::...||:.:||..||.:      |||.||.      ..|::||.|:...
Zfish    96 DRKFVFFLDPCNIDIIQRKIKSMALCVSQCPTE------ELLTYYDLKRFAMMNGSELCSYELPG 154

  Fly   139 QQLTTAGNDAKTFNFLGPCPSFPVHESS--PVLHRCVPKGT------GEKVQNYY---DMLNNWD 192
            .:..:.   .:.|:   .||..||.||.  ||.:||.|...      .|.|..:.   .|||
Zfish   155 HKYPSL---PERFD---KCPKLPVPESKALPVFNRCTPVDISCYAKFAEAVVTFVSDNSMLN--- 210

  Fly   193 VAQQFVGDIYSTWHIIAMVCGLALLISIALVTMMHWLSRIVSWIICVLVIVASVALTVALWYAYY 257
               :.:..:.::..||..:|.|||::|:.|:.::.::|.::.||:..||::.|:..|..||:.|.
Zfish   211 ---RLIAGVAASKEIIVGLCLLALVLSMILMVIIRYISAVLVWILTALVVLGSLGGTSVLWWLYI 272

  Fly   258 NIRNKSGVNTQYSMLEEFVRNQ-------------QAVLTLAVLATITMIILIVVIYFLKNKLAG 309
            :.|    :....:|.::....:             |.:|..||.||:...||::::.|::.::|.
Zfish   273 DYR----MTMNETMTKDLTETEEPNGGMKPTKDHAQGLLIYAVSATVFTGILLLLMLFMRKRVAL 333

  Fly   310 LSALFEEAGQCMMNLPGLLIAPLLAFLVLIAFLSFWVAVIICLATASSPGQSPIAPFDNSKAHQQ 374
            ..|||..||:..::||.|.:.|...||.|..|..:|:.|::.|.|..:|.::
Zfish   334 TIALFHVAGKVFIHLPLLALQPFCTFLALSLFWVYWIMVLLFLGTTGNPEKN------------- 385

  Fly   375 PLPANALFVSNSTDVNDLRPNARVEYADAGVLRSMFWIYVVGLIWTVEFIFACQQFALAAAVAFW 439
                              .....||:..:|.|:.|.|.:.|||||..|||.||||..:|.||..:
Zfish   386 ------------------EDTGLVEFRLSGALQYMTWYHAVGLIWISEFILACQQMTVAGAVVTY 432

  Fly   440 YFQKPTS----TPTFYAIGKLVKYHLGTVAKGSFVITIFKIPRLILTYLYAKLKKGEDKGSECAA 500
            ||.:..:    ||...::.:||:|||||||||||:||:.|||||||.|::.:||   .|.:.||.
Zfish   433 YFTRDKTKLPVTPILSSVLRLVRYHLGTVAKGSFIITLVKIPRLILMYIHNQLK---GKENACAR 494

  Fly   501 CCLKCCICGFWLLEKFIRFLNHNAYTVVAIESINFCPAAGIAWNAMATNVLQVATINSVGDFILF 565
            |.||.|||..|.|||.:.:||.|||...||.|.:||.:|..|:..:..|.|:|||||:||||:||
Zfish   495 CMLKACICCLWCLEKCLNYLNQNAYAATAINSTSFCTSARDAFMILVENALRVATINTVGDFVLF 559

  Fly   566 LGKVVVAALSGLIGIVLLKDKPGLNFYMAPVIIIIIFSFFIAHIILSLFEMVVDTLFLCVCED-K 629
            ||||::...:...|::.|..:.....::.|:||:.:|:|.:||..||:||:|||.||||...| |
Zfish   560 LGKVLIVTCTAFAGVLALNYQRDYTEWVLPLIIVCLFAFLVAHCFLSIFEIVVDVLFLCFAIDTK 624

  Fly   630 TLNGRSGR----------WAQSNLAKLVGEE-----PLQPGEEPPIEVVQMM 666
            ..||..||          :.:::...:..||     ..:|.||..:..|:.|
Zfish   625 YNNGTPGREFYMDKALMEFVENSRRSMAMEERGRSKRARPKEEVELTEVKAM 676

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ctl1	NP_647884.1	Choline_transpo	287..629	CDD:461337	138/346 (40%)
slc44a1b	XP_021336769.1	Choline_transpo	311..622	CDD:461337	137/344 (40%)