Protein Alignment Ctl1 and slc44a4

DIOPT Version :10

• Sequence 1: NP_647884.1
• Gene: Ctl1 / 38523
• FlyBaseID: FBgn0035523
• Length: 691
• Species: Drosophila melanogaster
• Sequence 2: XP_073786724.1
• Gene: slc44a4 / 393385
• ZFINID: ZDB-GENE-040426-1371
• Length: 729
• Species: Danio rerio
• Alignment Length: 769
• Identity: 196/769 - (25%)
• Similarity: 346/769 - (44%)
• Gaps: 158/769 - (20%)

  Fly     1 MGCAESKDGEGEAQNNRP-KY----------RSCTDTCWLAIYIIFWLFLIVIAIFSFVYGNPLR 54
            ||..:.::.:..::...| :|          |||||.....::::.....:|:.|.:::||:|..
Zfish     1 MGKKKQEEEQNSSEYGAPAQYDPTFNGPIHKRSCTDIICCVLFMLVITGYMVVGILAWLYGDPRH 65

  Fly    55 IINGYDSFGNTCGVKYNEKFQGFPLSGMNTLDKPELFYFDVKELK-----------------KSL 102
            ::...:|.|..||:..|:             :||.:.|||:  ||                 .:.
Zfish    66 VLYPRNSTGMFCGIGQNQ-------------NKPSVLYFDI--LKCATATNIMAAALQGLQCPTT 115

  Fly   103 KICVKSCPA-------KTMTKGSELLEYYSQ-------------------TGTQLCKYDYNMQQL 141
            ::||.|||:       ......::..:|:.|                   ...:||.|.|
Zfish   116 QVCVSSCPSGFWALSPLAYLPNAKPADYFQQELCVPSLQLKDTTYTVMEIINKELCPYYY----- 175

  Fly   142 TTAGNDAKTFNFLGPC--------------------PSFPVHES-SPVLHRCVPKGTGEKVQNYY 185
                  ..|.:.||.|                    |...:::: |.:.:.....|....:.|.:
Zfish   176 ------TPTTSVLGRCLPSLGGSAYNPSNIPANFSLPGLSINQTLSTIANATSAGGASNDLTNSF 234

  Fly   186 DMLNNWDVAQQFVGDIYSTWHIIAMVCGLALLISIALVTMMHWLSRIVSWIICVLVIVASVALTV 250
            :|.   ||..:...|...||..|.....:|:::|:..:.::.:.:.::.||:...|:...   ..
Zfish   235 NMK---DVGLRIFEDFAKTWQWIVAGLVIAMVVSVLFLLLLRFTAPVLIWILIFGVLAVG---AF 293

  Fly   251 ALWYAYYNIRNKSGVNTQYSMLEEFVRNQQAVLT-----LAVLATITMI--ILIVVIYFLKNKLA 308
            .:||.|.:..:.:..|..:|.: .|..|.|..|.     ||.|..:.::  :||:.:.||:.::.
Zfish   294 GIWYCYNDYMSLASSNLTFSNV-GFTTNVQVYLQVRDTWLAFLIILCIVEAVLILALIFLRTRIL 357

  Fly   309 GLSALFEEAGQCMMNLPGLLIAPLLAFLVLIAFLSFWVAVIICLATASSPGQSPIA------PFD 367
            ...||.:|..:.:.::...|:.|::.|::|:..:|:|....:.|||:.:|....:|      ...
Zfish   358 IAIALIQETSKALGHMMSTLLYPVVTFVLLLVCVSYWGITALYLATSGAPIYKVVALNATQGDCS 422

  Fly   368 NSKAHQ--QPLPANALFVSNSTDVNDLRPNAR---VEYADAGVL-RSMF--WIY-VVGLIWTVEF 423
            |.:|:|  .|...|:...|:.       |:||   :.|...|:. |::|  .|| ||..:|.|.|
Zfish   423 NIQANQTCDPQTFNSSRYSSC-------PSARCVFINYNTEGLFQRNLFNLQIYNVVAFLWCVNF 480

  Fly   424 IFACQQFALAAAVA--FWYFQKPTSTPTF---YAIGKLVKYHLGTVAKGSFVITIFKIPRLILTY 483
            :.|.....||.|.|  :|.|.||...|||   .:..:.::||:|::|.|:.::|:.:|.|:||.|
Zfish   481 VIALGHCTLAGAFASYYWAFSKPADIPTFPLTQSFMRALRYHVGSLAFGALILTLVQIVRIILEY 545

  Fly   484 LYAKLKKGEDKGSECAACCLKCCICGFWLLEKFIRFLNHNAYTVVAIESINFCPAAGIAWNAMAT 548
            |..|.|..::..:....||||||   ||.|||||:|:|.|||.::||...|||.:|..|:..:..
Zfish   546 LDHKFKAAQNPCARFLMCCLKCC---FWCLEKFIKFINRNAYIMIAIYGKNFCVSAKNAFFLLMR 607

  Fly   549 NVLQVATINSVGDFILFLGKVVVAALSGLIGIVLLKDK---PG-------LNFYMAPVIIIIIFS 603
            |:::|..::.|.|.:||.||::|....|::.......:   ||       ||:|..|:|.::..:
Zfish   608 NIVRVVVLDKVTDLLLFFGKLLVVGGIGVLAFFFFSGRIQLPGNTFQTAALNYYWMPIITVVFGA 672

  Fly   604 FFIAHIILSLFEMVVDTLFLCVCEDKTLNGRSGR---WAQSNLAKLVGEEPLQP 654
            :.|||...|::.|.|||||||..||...|..|..   :...||.|::.::..||
Zfish   673 YLIAHGFFSVYNMGVDTLFLCFLEDLERNDGSAEKPYFMSKNLMKILNKKNKQP 726

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ctl1	NP_647884.1	Choline_transpo	287..629	CDD:461337	120/373 (32%)
slc44a4	XP_073786724.1	None