Protein Alignment Ctl1 and Slc44a5

DIOPT Version :10

• Sequence 1: NP_647884.1
• Gene: Ctl1 / 38523
• FlyBaseID: FBgn0035523
• Length: 691
• Species: Drosophila melanogaster
• Sequence 2: XP_063138373.1
• Gene: Slc44a5 / 365962
• RGDID: 1564620
• Length: 719
• Species: Rattus norvegicus
• Alignment Length: 725
• Identity: 190/725 - (26%)
• Similarity: 329/725 - (45%)
• Gaps: 134/725 - (18%)

  Fly     5 ESKDGE----GEAQNNRPKY------RSCTDTCWLAIYIIFWLFLIVIAIFSFVYGNPLRIINGY 59
            ||.:.|    |:.:...|.:      ||.||.....|:::|.:..|::.:.::|:|:|.::....
  Rat    11 ESTEFEDQDLGDPRRYDPDFQGPTTKRSSTDVMCCMIFVLFIMGYILLGLLAWVHGDPRKMAYPT 75

  Fly    60 DSFGNTCGVKYNEKFQGFPLSGMNTLDKPELFYFDVKELK----------KSLKICVKSCPAKTM 114
            ||.|..||.|           |....:|..||||::....          .:.:|||..||.:.:
  Rat    76 DSQGQFCGQK-----------GTPNENKTVLFYFNIFRCTGTSMMLRLQCSTTQICVSRCPERFL 129

  Fly   115 T---------KGSELLEYYSQTGTQLCKYDYNMQQLTTAGNDAKTFNFL---GPCPSFPVHESSP 167
            |         :.....|||    .|.||         ......:|...|   |.|| ..|:.|.|
  Rat   130 TYVDMQILNKEDKNYWEYY----RQFCK---------AQARPVETLADLLSSGDCP-LAVYPSRP 180

  Fly   168 VLHRCVP------------------KGTGEK---------VQNYYDMLNNWDVAQQFVGDIYSTW 205
            .|.||||                  .|.|:|         .....|:::...:..:.:.|..::|
  Rat   181 FLQRCVPDFSAINGNLTLGSRMHFEDGGGQKRTVVELREAASGISDVIDARAIGLKVLEDYSTSW 245

  Fly   206 HIIAMVCGLALLISIALVTMMHWLSRIVSW--IICVLVIVASVALTVALWYAY--YN-IRNKS-- 263
            ..|.:...:|:.:|...:.::.:.:..:.|  |..||.|:.     ..:||.:  || |:.|.
  Rat   246 KWILIGLTIAMALSWTFLVLLRFTAGFLFWFFIFGVLGIIG-----YGIWYCFLEYNSIQQKPQS 305

  Fly   264 -------GVNTQYSMLEEFVRNQQAVLTLAVLATITMIILIVVIYFLKNKLAGLSALFEEAGQCM 321
                   |:.|:.:|   |...::...::.::.:...:::|:|:.||:.::.....|.:|..:.:
  Rat   306 AIWMYGIGIQTRLNM---FFHLKETWFSMMIILSAIEVVIIIVLIFLRTRIQVAIILLKEGSKAI 367

  Fly   322 MNLPGLLIAPLLAFLVLIAFLSFWVAVIICLATASSPGQSPIAPFDNSKAHQQPLPANALFVSNS 386
            ..||..|:.|.|.|::|...:|:|....:.|||:..|....:.| :....|:.......:|  .:
  Rat   368 GYLPSALVYPFLTFILLSICISYWAVTAVFLATSGVPIFKVMVP-EGECIHEDEACDPEIF--PN 429

  Fly   387 TDVNDLRPNARVEYADAGVLRSMFWIYVV--------GLIWTVEFIFACQQFALAAAVA--FWYF 441
            ||:....|.|...:|..|. |||:..|:.        ..:|.:.|:.|..|.|||.|.|  :|..
  Rat   430 TDIPKACPGASCNFAFYGG-RSMYHNYIATFQLYNLFAFLWLINFVIALGQCALAGAFASYYWAM 493

  Fly   442 QKPTST---PTFYAIGKLVKYHLGTVAKGSFVITIFKIPRLILTYLYAKLKKGEDKGSECAACCL 503
            :||...   |.|.|.|:.|:||.|::|.||.::...::.::|:.||..:|||.::..::...|||
  Rat   494 RKPEDIPRYPLFTAFGRAVRYHTGSLAFGSLILAFVQMFKVIVEYLDRRLKKAQNSAAQFLHCCL 558

  Fly   504 KCCICGFWLLEKFIRFLNHNAYTVVAIESINFCPAAGIAWNAMATNVLQVATINSVGDFILFLGK 568
            :||   ||.|||.::|||.|||.::|:...|||.:...|:..:..|:|:|...:.|..|:|.|||
  Rat   559 RCC---FWCLEKMVKFLNRNAYIMIALYGKNFCESTRDAFYLLMRNILKVKVTDEVTYFVLLLGK 620

  Fly   569 VVVAALSGLIGIVLLKDK--------PGLNFYMAPVIIIIIFSFFIAHIILSLFEMVVDTLFLCV 625
            |:|:.:.|::..:|..::        ..||:|..|.:.::..|:.|||...|::.|.|:|:|:|.
  Rat   621 VLVSGIVGVLAFLLFTERLHEIVEGPTSLNYYWVPFLTLVFGSYLIAHGFFSVYSMCVETIFICF 685

  Fly   626 CEDKTLNGRS 635
            |||...|..|
  Rat   686 CEDLERNDGS 695

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ctl1	NP_647884.1	Choline_transpo	287..629	CDD:461337	111/362 (31%)
Slc44a5	XP_063138373.1	None