Protein Alignment Ctl1 and slc44a2

DIOPT Version :10

• Sequence 1: NP_647884.1
• Gene: Ctl1 / 38523
• FlyBaseID: FBgn0035523
• Length: 691
• Species: Drosophila melanogaster
• Sequence 2: XP_005165806.2
• Gene: slc44a2 / 324345
• ZFINID: ZDB-GENE-030131-3065
• Length: 847
• Species: Danio rerio
• Alignment Length: 785
• Identity: 219/785 - (27%)
• Similarity: 368/785 - (46%)
• Gaps: 134/785 - (17%)

  Fly     5 ESKDGE---GEAQNNRPKY------RSCTDTCWLAIYIIFWLFLIVIAIFSFVYGNPLRIINGYD 60
            |.|:.|   ||.:...|.:      |.|||.....::|:..|....:.|.::..|:|.::|...|
Zfish     4 EEKNPESKYGEPRKFDPTFKGPIYNRGCTDILCCILFILALLGYFAVGILAWSQGDPRKVIYPTD 68

  Fly    61 SFGNTCGVKYNEKFQGFPLSGMNTLDKPELFYFDVKELKKSL----------KICVKSCPAKTMT 115
            |.|..||.      .|.||.     .||.||||::.:....|          :|||:.||.|.||
Zfish    69 STGQFCGQ------AGTPLE-----KKPLLFYFNIMKCASPLVLLEFQCPTTQICVEKCPDKFMT 122

  Fly   116 -----KGSELLEYYSQTGTQLCKYDYNMQQLTTAGNDAKTFNFLGPCPS--FPVHESSPVLHRCV 173
                 |......||    ||.||...:|.:      :|......|.|||  ||   |.....||:
Zfish   123 LVNALKSQSDKTYY----TQFCKEGVDMTK------NAPQILSEGLCPSILFP---SKNFTRRCL 174

  Fly   174 P-----KG----TGEKVQ---------NYYDMLNNWD----------VAQQFVGDIYSTWHIIAM 210
            |     ||    .|.:.|         |..|:||...          ||.:...|...:||.|.:
Zfish   175 PALETMKGGVVVIGNETQFTVDQGEVINATDLLNAAKKSNVVVEARAVAMRIFEDYTQSWHWILL 239

  Fly   211 VCGLALLISIALVTMMHWLSRIVSWIICVLVIVASVALTVALWYAYYNIRNKS---------GVN 266
            ...:|:|||:..:.::.:|:.::.|::.::||:.........:..|.:::.::         |:.
Zfish   240 GLVIAMLISLIFILLLRFLAGVMVWVMIIMVIIVIGYGIFHCYMQYASLKGQAGSDVTIKDLGLQ 304

  Fly   267 TQYSMLEEFVRNQQAVLTLAVLATITMIILIVVIYFLKNKLAGLSALFEEAGQCMMNLPGLLIAP 331
            |.:|:   :::.||..|...::..|...::::::.||:.:|....||.:||.:.:.::...|..|
Zfish   305 TDFSV---YLQIQQTWLAFMIILCIVEAVILLLLIFLRKRLLIAIALIKEASKAIGHVMSSLFYP 366

  Fly   332 LLAFLVLIAFLSFWVAVIICLATASSPGQSPIAPFDNSKAHQQPLPAN-ALFVSNSTDVNDLRPN 395
            ||.:.::...:::|....:.|:|::.|   ....|:.|.........| |.|  |:::|....|:
Zfish   367 LLTYALMSLVIAYWAITAVFLSTSNEP---IYKVFNTSNCSYSRATCNPATF--NTSNVTTECPD 426

  Fly   396 ARVEYADAGVLRSMF--WIYVVG------LIWTVEFIFACQQFALAAAVA--FWYFQKPTSTPT- 449
            |...:|..|. .:::  |:.|..      ..|.|.|:.|..|..||.|.|  :|.|:||...|.
Zfish   427 AECLFAFYGG-ETLYHKWLIVFQFYNLFLFFWCVNFVIALGQVTLAGAFASYYWAFKKPDDMPAF 490

  Fly   450 --FYAIGKLVKYHLGTVAKGSFVITIFKIPRLILTYLYAKLKKGEDKGSECAACCLKCCICGFWL 512
              |.::|:.::||.||:|.||.::.|.::.|::|.||..|||..::|.::....|||||   ||.
Zfish   491 PIFNSLGRALRYHTGTLAFGSLILAIVQVIRVVLEYLDQKLKGAQNKFAKFLLSCLKCC---FWC 552

  Fly   513 LEKFIRFLNHNAYTVVAIESINFCPAAGIAWNAMATNVLQVATINSVGDFILFLGKVVVAALSGL 577
            |||||:|:|.|||.:|||...|||.:|..|:..:..|:::||.::.|.||:|||||:::..:.|:
Zfish   553 LEKFIKFINRNAYIMVAIYGKNFCTSARDAFFLLMRNIVRVAVLDKVTDFLLFLGKLLIVGIVGI 617

  Fly   578 IGIVLLKDK--------PGLNFYMAPVIIIIIFSFFIAHIILSLFEMVVDTLFLCVCEDKTLN-G 633
            ........|        |.||:|..|::.::..::.|||...|::.|.|||||||.|||...| |
Zfish   618 CSFFFFTGKIKIAQDVTPALNYYWVPILTVVFGAYLIAHGFFSVYAMCVDTLFLCFCEDLERNDG 682

  Fly   634 RSGR--WAQSNLAKLVG-EEPLQPGEEPPIEVVQMMPINKQPF---------SITRLPQSDPEVA 686
            .|.:  :....|.:::. |:.::..:...:.|:|:....:.|.         ..|.|.|...|..
Zfish   683 SSDKPFFMSPELHQILSIEKSIEETDHAEVPVIQVQAEEEIPLQENGEVQLKQQTVLKQDQEEET 747

  Fly   687 PMSAD 691
            |::.:
Zfish   748 PLNQE 752

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ctl1	NP_647884.1	Choline_transpo	287..629	CDD:461337	118/363 (33%)
slc44a2	XP_005165806.2	Choline_transpo	322..678	CDD:461337	119/364 (33%)
		PTZ00341	<636..>814	CDD:173534	32/117 (27%)