Protein Alignment Ctl1 and Slc44a3

DIOPT Version :9

• Sequence 1: NP_647884.1
• Gene: Ctl1 / 38523
• FlyBaseID: FBgn0035523
• Length: 691
• Species: Drosophila melanogaster
• Sequence 2: XP_038958014.1
• Gene: Slc44a3 / 295417
• RGDID: 1305808
• Length: 652
• Species: Rattus norvegicus
• Alignment Length: 695
• Identity: 203/695 - (29%)
• Similarity: 327/695 - (47%)
• Gaps: 108/695 - (15%)

  Fly    17 RPK-YRSCTDTCWLAIYIIFWLFLIVIAIFSFVYGNPLRIINGYDSFGNTCGVKYNEKFQGFPLS 80
            ||: ||.||||.||.::.:||..|:.|..:|.|.|...|::.|||||||.|| |.|...:|.|||
  Rat    21 RPQIYRKCTDTAWLVLFFLFWTGLVFIMGYSVVAGAAGRLLFGYDSFGNVCG-KRNSPVEGAPLS 84

  Fly    81 GMNTLDKPELFY-----FDVKELKKS-LKICVKSCPAKTMTKGSELLEYYSQTGTQLCKYDYNMQ 139
            |.:...|..:|:     .:||:..:. :.:||.|||.|.:....|:..:.:..|:.||.|..|
  Rat    85 GQDMTLKKHVFFMNACNLEVKDRGRGPMALCVSSCPEKQLDTLEEVQLFANINGSFLCVYSLN-- 147

  Fly   140 QLTTAGNDAKTFNFL-GP-----CPSFPVHESS--PVLHRCVPKGTGEKVQNYYD-MLNNWDVAQ 195
                      :||:. .|     ||..||..|.  |:.:||:|: |.|....:.. :||:.|...
  Rat   148 ----------SFNYTQSPSADRLCPRLPVPPSKPFPLFNRCIPQ-TPECYSLFASVLLNDADALH 201

  Fly   196 QFVGDIYSTWHIIAMVCGLALLISIALVTMMHWLSRIVSWIICVLVIVASVALTVALWYAYYNIR 260
            :.:..|.:....|..:|.....:|:|::....::|.::..||..|||:..:.:....|:.||:..
  Rat   202 RILSGIMAGRDTILGLCAFVFALSLAMLFTFRFISTLLVHIIISLVILGLLFVCGVFWWLYYDYT 266

  Fly   261 NKSGVNTQYSMLEEFVRNQQAVLTLAVLATITMIILIVVIYFLKNKLAGLSALFEEAGQCMMNLP 325
            |  .::|:....:|   |.:.:|..||:.|:..::|:.:|:.|:.::.....|.....:.:...|
  Rat   267 N--DLSTELDTEKE---NMKCMLAFAVITTVVTVVLLALIFTLRKRVKLTVELLRVTNKAISRCP 326

  Fly   326 GLLIAPLLAFLVLIAFLSFWVAVIICLATASSPGQSPIAPFDNSKAHQQPLPANALFVSNSTDVN 390
            .||:.||..|.:|:.|...||||::.|.||.:.
  Rat   327 FLLLQPLWTFAILVFFWVLWVAVLLSLGTAGTA-------------------------------- 359

  Fly   391 DLRPNARVEYADAGVLRSMFWIYVVGLIWTVEFIFACQQFALAAAVAFWYFQK----PTSTPTFY 451
            .:....:|||.....:|.::|.:::|||||.|||..||:..:|.|:...||.:    |.:.|...
  Rat   360 QVMEGGQVEYKPLSGIRYLWWYHLIGLIWTSEFILTCQRMTVAGAMVTCYFNRNQNDPPARPILS 424

  Fly   452 AIGKLVKYHLGTVAKGSFVITIFKIPRLILTYLYAKLK--------KGEDKGSECAACCLKCCIC 508
            ::..|..||.||..|||.::|:.:|||:|..|:|:.:|        :||          .:|..|
  Rat   425 SLSTLFCYHQGTAVKGSLLLTVTRIPRVIFMYIYSTVKERQHSAWPRGE----------FRCSYC 479

  Fly   509 GFWLLEKFIRFLNHNAYTVVAIESINFCPAAGIAWNAMATNVLQVATINSVGDFILFLGKVVVAA 573
            |.|.|..:...||.:||...||...:||.:|..|...::.|...:.::|..|:||:|||||:|..
  Rat   480 GLWCLTNYPYHLNQDAYAAAAINGTDFCTSAKDAHTIISKNSSHLTSVNCFGNFIIFLGKVLVVC 544

  Fly   574 LSGLIGIVLLKDKPGLNFYMAPVIIIIIFSFFIAHIILSLFEMVVDTLFLCVCEDKTLNGRSG-- 636
            .|...|::.......|..:..|::::..|::..||..||:||.|:||||||...|...|..|.
  Rat   545 FSVFGGLMAFNYNRALQVWAIPLLLVAFFAYLAAHSFLSVFETVLDTLFLCFAVDLETNDGSSEK 609

  Fly   637 -------------RWAQSNLAKLVGEEPLQPGEEPPIEVVQMMPI 668
                         |....|.|:..|.:...|.||.    .::.||
  Rat   610 PYFMDPGFLSFVKRTDHFNNARSQGHKNSLPNEEG----TELRPI 650

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ctl1	NP_647884.1	DUF4481	<207..>316	CDD:291466	25/108 (23%)
		Choline_transpo	286..629	CDD:282384	105/354 (30%)
Slc44a3	XP_038958014.1	Choline_transpo	302..601	CDD:398290	101/340 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166343769
Domainoid	1	1.000	265	1.000	Domainoid score	I1826
eggNOG	1	0.900	-	-		E1_KOG1362
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	395	1.000	Inparanoid score	I1899
OMA	1	1.010	-	-		QHG45602
OrthoDB	1	1.010	-	-		D167290at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm45896
orthoMCL	1	0.900	-	-		OOG6_104769
Panther	1	1.100	-	-	O	PTHR12385
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X2976
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	13	12.810