Protein Alignment Ctl1 and Slc44a3

DIOPT Version :10

• Sequence 1: NP_647884.1
• Gene: Ctl1 / 38523
• FlyBaseID: FBgn0035523
• Length: 691
• Species: Drosophila melanogaster
• Sequence 2: NP_663369.2
• Gene: Slc44a3 / 213603
• MGIID: 2384860
• Length: 656
• Species: Mus musculus
• Alignment Length: 681
• Identity: 206/681 - (30%)
• Similarity: 328/681 - (48%)
• Gaps: 80/681 - (11%)

  Fly    17 RPK-YRSCTDTCWLAIYIIFWLFLIVIAIFSFVYGNPLRIINGYDSFGNTCGVKYNEKFQGFPLS 80
            ||: ||.||||.||.::.:||..|:.|..:|.|.|...|::.|||||||.|| |.|...:|.|||
Mouse    25 RPQIYRKCTDTPWLVLFFLFWTGLVFIMGYSVVAGAAGRLLFGYDSFGNVCG-KKNSPVEGAPLS 88

  Fly    81 GMNTLDKPELFYFDVKELKKS------LKICVKSCPAKTMTKGSELLEYYSQTGTQLCKYDYNMQ 139
            |.:...|..:|:.:...|:..      ..:||.|||.|.:....|:..:.:..|:.||.|..|..
Mouse    89 GQDMTLKKHVFFMNACNLEVKDRGLGPTALCVSSCPEKQLDTLEEVQLFANINGSFLCVYSLNSF 153

  Fly   140 QLTTAGNDAKTFNFLGPCPSFPVHESS--PVLHRCVPKGTGEKVQNYYDML-NNWDVAQQFVGDI 201
            ..|.: :.|.|.     ||..||..|.  |:.:||:|: |.|....:..:| |:.|...:.:..|
Mouse   154 NYTQS-SSADTL-----CPRLPVPPSKPFPLFNRCIPQ-TPECYSLFASVLINDADALHRILSGI 211

  Fly   202 YSTWHIIAMVCGLALLISIALVTMMHWLSRIVSWIICVLVIVASVALTVALWYAYYNIRNKSGVN 266
            .:....|..:|.....:|:|::....::|.::..||..|||:..:.:...||:.||:..|  .::
Mouse   212 MAGRDTILGLCVFTFALSLAMLFAFRFISTLLIHIIISLVILGLLFVCGVLWWLYYDYTN--DLS 274

  Fly   267 TQYSMLEEFVRNQQAVLTLAVLATITMIILIVVIYFLKNKLAGLSALFEEAGQCMMNLPGLLIAP 331
            |:....:|   |...:|..|:::|:..::|:.:|:.|:.::.....|.....:.:.:.|.||..|
Mouse   275 TELDTEKE---NMNCMLAFAIISTVVTVLLLALIFTLRKRIKLTVELLHVTNKAISSCPFLLFQP 336

  Fly   332 LLAFLVLIAFLSFWVAVIICLATASSPGQSPIAPFDNSKAHQQPLPANALFVSNSTDVNDLRPNA 396
            |....:||.|...||||::.|.||.:.                                .:....
Mouse   337 LWTCAILIFFWVLWVAVLLSLGTAGTA--------------------------------QVMEGG 369

  Fly   397 RVEYADAGVLRSMFWIYVVGLIWTVEFIFACQQFALAAAVAFWYFQK----PTSTPTFYAIGKLV 457
            :|||.....:|.|:|.:::|||||.|||.|||:..:|.|:...||.:    |.:.|...::..|.
Mouse   370 QVEYKPLSGIRYMWWYHLIGLIWTSEFILACQRMTVAGAMVACYFNRNQNDPPARPILSSLFVLF 434

  Fly   458 KYHLGTVAKGSFVITIFKIPRLILTYLYAKLKKGEDKGSECAACCLKCCICGFWLLEKFIRFLNH 522
            .||.||..||||::|:.:|||:|...:|:.||  |.:.|..:....:|..||.|.|.|::..||.
Mouse   435 CYHQGTAVKGSFLLTVTRIPRVIFMCIYSTLK--EPQRSAWSRGEFRCSHCGLWCLLKYLYHLNQ 497

  Fly   523 NAYTVVAIESINFCPAAGIAWNAMATNVLQVATINSVGDFILFLGKVVVAALSGLIGIVLLKDKP 587
            :|||..||...:||.:|..|...:|.|...:.::|..|:|::|||||:|...|...|::......
Mouse   498 DAYTATAINGTDFCTSAKDAHTIIAKNSSHLTSVNCFGNFVIFLGKVLVVCFSIFGGLMAFNYSR 562

  Fly   588 GLNFYMAPVIIIIIFSFFIAHIILSLFEMVVDTLFLCVCEDKTLNGRSG---------------R 637
            .|..:..|::::..|:..:||..||:||..:|.||||...|...|..|.               |
Mouse   563 ALQVWAIPLLLVAFFACVVAHSFLSVFETALDILFLCFAVDLETNDGSSEKPYFMDPGFLSVIKR 627

  Fly   638 WAQSNLAKLVGEEPLQPGEEPPIEVVQMMPI 668
            ....|.||..|::...|.||.    .::.||
Mouse   628 TNNLNNAKSQGQKDALPNEEG----TELQPI 654

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ctl1	NP_647884.1	Choline_transpo	287..629	CDD:461337	106/345 (31%)
Slc44a3	NP_663369.2	Choline_transpo	292..605	CDD:461337	107/346 (31%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	634..656		8/25 (32%)