Protein Alignment Ctl1 and slc44a4

DIOPT Version :10

• Sequence 1: NP_647884.1
• Gene: Ctl1 / 38523
• FlyBaseID: FBgn0035523
• Length: 691
• Species: Drosophila melanogaster
• Sequence 2: XP_017952306.1
• Gene: slc44a4 / 100489321
• XenbaseID: XB-GENE-485457
• Length: 708
• Species: Xenopus tropicalis
• Alignment Length: 749
• Identity: 195/749 - (26%)
• Similarity: 339/749 - (45%)
• Gaps: 145/749 - (19%)

  Fly     6 SKDGEGEAQNNRP------KYRSCTDTCWLAIYIIFWLFLIVIAIFSFVYGNPLRIINGYDSFGN 64
            :.|..||.....|      |.|||||.....::::|.|..:|:.|.:::||:|.::|...:|.|.
 Frog     2 ASDEYGEPAKYDPSFKGPIKKRSCTDIICCVLFMVFLLGYMVVGILAWLYGDPRQVIYPRNSTGM 66

  Fly    65 TCGVKYNEKFQGFPLSGMNTLDKPELFYFDVKELK-----------------KSLKICVKSCPA- 111
            .||:..|   ||          ||.:.|:|:  ||                 .:.::||.:|||
 Frog    67 YCGIGEN---QG----------KPNVLYYDL--LKCITGTNILAAAMNGLQCPTTQVCVANCPAD 116

  Fly   112 -KTMTKGSELLEYYSQTGTQLCKYDYNMQQ--LTTAGNDAKTFNFLGPCPSFPVHESSPVLHRCV 173
             |....||...:.|.|   :.|:...|:..  ||.|...|:..     ||.|.| .|:...:||.
 Frog   117 FKWAKPGSTPADVYLQ---EYCQPSINLTNTALTVAEIAAREL-----CPVFLV-PSASFFNRCF 172

  Fly   174 P-------------------------KGTGEKVQNYYDMLNNWDVAQQFVGDIYSTWHIIAMVCG 213
            |                         |..|:    ..|..|..:|.::...|...:|..|.....
 Frog   173 PGSNLSFPSNFAINGLSVNQSKDSISKAAGQ----ILDSFNFQNVGKKIFEDFAKSWPWIITALV 233

  Fly   214 LALLISIALVTMMHWLSRIVSWIICVLVIVASVALTVALWYAYYNIRNKSG---VNTQYSM-LEE 274
            :|:::|:..:.::.:.:.|:.|:: ::.::..:...:...|..|:..||.|   .|..::. |..
 Frog   234 IAMVVSLLFLILLRFTAGILVWVL-IVGVIGVIGYGIYHCYMEYDTLNKQGETVANVGFTFNLGV 297

  Fly   275 FVRNQQAVLTLAVLATITMIILIVVIYFLKNKLAGLSALFEEAGQCMMNLPGLLIAPLLAFLVLI 339
            :.|.::..|.:.::..:...||::|:.||:.::....||.:||.:.:.::...|..||:.|::||
 Frog   298 YFRVKETWLAILIVLAVIEAILLLVLLFLRKRILIAIALIKEASKAIGHIMSSLFYPLVTFVLLI 362

  Fly   340 AFLSFWVAVIICLATASSP------------------GQSPIAPFDNSKAHQQPLPANALFVSNS 386
            ..:::|....:.|||:.:|                  |.....|...|.|......|..:|
 Frog   363 VCVAYWGMTALYLATSGAPLYRISTVNTSVPGCENITGNETCNPMTFSNASTSCKEARCIF---- 423

  Fly   387 TDVNDLRPNARVEYADAGVLRSMFW---IY-VVGLIWTVEFIFACQQFALAAAVA--FWYFQKPT 445
                       ..|.:.|:.::..:   || |:|.:|.:.|:.|..|..||...|  :|.|.||.
 Frog   424 -----------YRYNNEGLFQTNLFNLQIYNVIGFLWCINFVIALGQCVLAGTFASYYWAFHKPK 477

  Fly   446 STPTFYAIG----KLVKYHLGTVAKGSFVITIFKIPRLILTYLYAKLKKGEDKGSECAACCLKCC 506
            ..| |:.:.    :.::||.|::|.|:.::||.::.|:||.||..|||..::..:....||||||
 Frog   478 DIP-FFPVAESFMRTLRYHTGSLAFGALILTIVQLIRIILEYLDHKLKGAQNPCTRFLLCCLKCC 541

  Fly   507 ICGFWLLEKFIRFLNHNAYTVVAIESINFCPAAGIAWNAMATNVLQVATINSVGDFILFLGKVVV 571
               ||.|||||:|||.|||.::|:...|||.:|..|:..:..|:::|..::.|.|.::|.||::|
 Frog   542 ---FWCLEKFIKFLNRNAYIMIAVYGKNFCVSAKNAFKLLMRNIVRVVVLDKVTDLLIFFGKLIV 603

  Fly   572 AALSGLIGIVLLKDK----------PGLNFYMAPVIIIIIFSFFIAHIILSLFEMVVDTLFLCVC 626
            ....|::.......:          |.||:|..|::.::|.|:.|:|...|::.|.|||||||..
 Frog   604 VGGVGVLAFFFFSGRIPIPNPAFQSPALNYYWIPILTVVIGSYMISHGFFSVYNMCVDTLFLCFL 668

  Fly   627 EDKTLNGRSGR---WAQSNLAKLVGEEPLQPGEE 657
            ||...|..|..   :...:|..::.::...|..|
 Frog   669 EDLERNDGSPEKPYYMSKSLMSILNKKNRPPKSE 702

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ctl1	NP_647884.1	Choline_transpo	287..629	CDD:461337	113/379 (30%)
slc44a4	XP_017952306.1	Choline_transpo	310..672	CDD:461337	114/380 (30%)